Gene Information

Name : pyk-3 (AHA_3052)
Accession : YP_857554.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3444421 - 3445869 bp
Length : 1449 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
TTGCACGGCGGAAACTCCTTAACCATGAAGACTGACATGAAAAAGACCAAAATCGTCTGCACCATCGGTCCCAAGACCGA
ATCCAAAGAAATGCTGGCCAAGATGCTGGACGCCGGCATGAACGTCATGCGCCTGAACTTCTCCCACGGCGACTACGCCG
AGCACGGTGGTCGCATCAGCAACCTGCGCGCTGTCATGGCCGAAACCGGCAAGCACGCAGCCATTCTGCTGGACACCAAG
GGTCCGGAAATCCGTACCATCAAGCTGGAAGGCGGCAACGACGTTGCCCTGGTCGCTGGCCAGACCTTCACCTTCACCAC
CGACCAGACCGTGGTTGGCAACAAAGACAAAGTGGCCGTGACCTATGCCGGTTTCGCCAACGACCTGCGCGTCGGCAACC
GCATCCTGGTTGACGATGGCCTGATCGGTCTGGACGTTATCGAGATCACCGAGCGCGAAGTCATCTGTAAAGTACTGAAC
AACGGCGATCTGGGCGAGAACAAGGGCATCAACCTGCCGGGCGTCTCCATCAAGCTGCCGGCCCTGGCCGAGAAAGACAA
GCGCGACCTGATCTTCGGTTGCGAGCAAGGCGTTGATTTCGTTGCCGCTTCCTTCATTCGCAAGAAAGAAGACGTGCTGG
AAATCCGTGAGCACCTGAAAGCCCACGGTGGCGAGAACATCCAGATCATCTCCAAGATCGAAAACCAGGAAGGCCTGGAC
AACTTCGACGAGATCCTGGCTGTTTCCGACGGCATCATGGTTGCTCGTGGCGACATGGGTGTCGAAATCCCGGTTGAAGA
AGTTATCTTCGCCCAGAAGATGATCATCGAGAAGTGCAACAAAGCCCGCAAAGTGGTCATCACCGCCACCCAGATGCTGG
ACTCCATGATCAAGAACCCGCGTCCGACCCGCGCCGAAGCCGGCGACGTGGCCAACGCCATCCTGGACGGTACCGACGCA
GTCATGCTGTCCGGTGAGTCCGCCAAGGGCAAATACCCGCTGGAAGCCGTGACCATCATGGCCACCATCTGCGAGCGTAC
CGATGCCGTGATGCCGTCCAACCTGTCTGCTGCCAACGACAGCAACAAGCTGCGCATCACCGAAGCGGTATGTAAAGGCG
CGGTAGAAACCTCCGAGAAGCTGGACGCCCCGCTGATCGTGGTTGCCACCGAAGGCGGCAAGTCTGCCAAGGCCATCCGC
AAGTACTTCCCGAAAGCCTGGATCCTGGCCATCACCACCAACAAGAAGACCGCTGCCCAGCTGGTACTGACCAAGGGTGT
GGTTGCTCACGTGGTTGACAGCATCGCCTCCACCGACGATTTCTATCGCATCGGTAAAGAAGCGGCGCTGGCCAGCGGCA
TGGGTCTGAAGGGTGACGTGGTTGTCATGGTCTCCGGTGCCCTGGTACCGAGCGGCACCACCAACACCGCTTCTGTTCAC
GTTCTTTAA

Protein sequence :
MHGGNSLTMKTDMKKTKIVCTIGPKTESKEMLAKMLDAGMNVMRLNFSHGDYAEHGGRISNLRAVMAETGKHAAILLDTK
GPEIRTIKLEGGNDVALVAGQTFTFTTDQTVVGNKDKVAVTYAGFANDLRVGNRILVDDGLIGLDVIEITEREVICKVLN
NGDLGENKGINLPGVSIKLPALAEKDKRDLIFGCEQGVDFVAASFIRKKEDVLEIREHLKAHGGENIQIISKIENQEGLD
NFDEILAVSDGIMVARGDMGVEIPVEEVIFAQKMIIEKCNKARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDA
VMLSGESAKGKYPLEAVTIMATICERTDAVMPSNLSAANDSNKLRITEAVCKGAVETSEKLDAPLIVVATEGGKSAKAIR
KYFPKAWILAITTNKKTAAQLVLTKGVVAHVVDSIASTDDFYRIGKEAALASGMGLKGDVVVMVSGALVPSGTTNTASVH
VL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 0.0 84
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 0.0 84
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 0.0 84
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 0.0 84

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk-3 YP_857554.1 pyruvate kinase VFG0479 Protein 0.0 84