Gene Information

Name : cvrA (AHA_1475)
Accession : YP_856013.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1607818 - 1609545 bp
Length : 1728 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCGTCACCATCAACAGTTTTTTCCTCGTCGCGGCCTTGTTGGTGGGCGCCAGTGTCCTGTTGAGCGCGCTCTC
CTCCCGTCTCGGTATCCCCATCCTGGTGATCTTCCTCGCCGTCGGCATGCTGGCCGGTGAAGATGGCCCCGGCGGCATCC
ACTTCGCCGACTACTCCATCGCCTATCTGGTGGGCAACCTGGCGCTCGCCATCATCCTGCTCGACGGCGGTATGCGCACC
CGGGTCTCCTCGTTTCGGGTCGCGCTCTGGCCCGCGCTCTCGCTGGCCACGGTCGGGGTGGCCATCACCACCGGCCTGAC
GGGCCTGGCCGCCGCCTGGCTGTTTGACCTCAACCTGATGCAGGGGATGCTGATCGGCGCCATCGTCGGCTCCACCGATG
CGGCGGCGGTCTTCTCCCTGCTCGGCGGACGCAGCCTCAACGAGCGGGTCAGCGCCACCCTGGAGATAGAATCGGGCAGC
AACGATCCCATGGCGGTGTTTCTCACCGTCACCCTGATCGAGGTGCTGGCCAGCGCCCAGCAAGACCTCAACGCCGGCTT
TCTGCTGCTGCAACTGCTCAAGCAGTTCGGGCTGGGCGCCGGCATCGGCCTTGGCGGCGGCTGGCTGCTGTGGAAACTCA
TCAACAGCGCCAAGCTGGCCCCCGGCCTCTACCCGCTGCTCACCGTCAGCGGCGGCCTGCTCATCTTCGCCCTCACCACG
GCGGTGGGCGGCAGCGGCATCCTCGCCATCTATCTCACCGGCCTCTTGCTCGGCAACCTCTCCCTGCGCAGTCGCAGCAC
CACCTTGTCGGTGCTGGACGGCCTGACCTGGCTCAGCCAGATCGGCATGTTTCTGGTGCTGGGGCTGCTCGCCTCCCCCC
ACAAGCTGCTGCCCATCGCCCTCCCGGCGCTGGCGCTGGCCATGTGGATGATCCTGTTTGCCCGCCCCATCTCGGTCTGG
ATCGGGCTGCTGCCGTTCAAGAACTTCGCCCCGCGCGAGCGCTGGTTCATCTCCTGGGTCGGCCTGCGCGGCGCGGTGCC
GATCATTCTGGCGGTGTTTCCCATGATGGCGGGGCTGCCCAACGCCCAGCTCTACTTCAATGTCGCCTTCTTCGTGGTGC
TGGTCTCGCTCATCTTGCAGGGCAGCTCGCTGCCGCTGGCCTCCAGGCTGGCGCGGGTGGAGGTGCCGGCGCCCCCCTCG
CCCATCAACCGCTCCGGGCTCGAGATCGATCTCGACAGCCAGTGGGAGACCTTCGTCTATCGCCTGAGCGACGAGAAGTG
GTGCATCGGCTCGCCGCTGCGGGATCTGCGCATGCCCAAGGGCACCCGCATCTGCGCCCTGTTCCGGGATCAGGAGCTGC
TGCACCCCTCGGGCAGTACCTGTCTGCAATCCGATGACATCCTCTGCGTCATCGGCCACGAGCGCGACCTGCCCGCCCTC
GGCCAGCTGTTCAGCCAGGCGCCGGAGCAGGATCTGGGCCCGCGCTTCTTCGGTGACTTCCTGCTGGAGGCGGCCGCCAA
CCTGGTGGATCTCGCCCCGCTCTATGGGCTGGATGTGAGCGAGGTGGCGGATCAGACCCTTGGCCATTTCATTGCCCACC
AGTTGGGCGATAATCTGGTGGTCGGCGACCACGTCGAATGGCAGGGACTGATCTGGACCGTGGCCGAAATGGACGAGGGT
GAGCCCCGCAAGATCGGGGTGCGCTTTCTGGAAGAAGATCCTGTCTGA

Protein sequence :
MDAVTINSFFLVAALLVGASVLLSALSSRLGIPILVIFLAVGMLAGEDGPGGIHFADYSIAYLVGNLALAIILLDGGMRT
RVSSFRVALWPALSLATVGVAITTGLTGLAAAWLFDLNLMQGMLIGAIVGSTDAAAVFSLLGGRSLNERVSATLEIESGS
NDPMAVFLTVTLIEVLASAQQDLNAGFLLLQLLKQFGLGAGIGLGGGWLLWKLINSAKLAPGLYPLLTVSGGLLIFALTT
AVGGSGILAIYLTGLLLGNLSLRSRSTTLSVLDGLTWLSQIGMFLVLGLLASPHKLLPIALPALALAMWMILFARPISVW
IGLLPFKNFAPRERWFISWVGLRGAVPIILAVFPMMAGLPNAQLYFNVAFFVVLVSLILQGSSLPLASRLARVEVPAPPS
PINRSGLEIDLDSQWETFVYRLSDEKWCIGSPLRDLRMPKGTRICALFRDQELLHPSGSTCLQSDDILCVIGHERDLPAL
GQLFSQAPEQDLGPRFFGDFLLEAAANLVDLAPLYGLDVSEVADQTLGHFIAHQLGDNLVVGDHVEWQGLIWTVAEMDEG
EPRKIGVRFLEEDPV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 3e-125 65
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 3e-125 65