Gene Information

Name : smpB (AHA_1443)
Accession : YP_855981.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1578180 - 1578668 bp
Length : 489 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGCAAAAAAAACAGTAAAAACAAAGCCGGGTCCAACACCATTGCACTCAACAGAAGCGCGCGCCACGAATACTTCAT
CGAAGAGAAGATCGAGGCGGGTCTGTCCCTGCAAGGGTGGGAAGTCAAATCTCTGCGGGCGGGCAAGGCCAACATCAGCG
AAGCCTATGTCATCTTCCGCGATGGTGAGGCCTACCTGTTCGGATCCAGCTTCCTGCCACTGCAAGCGGCTTCCAGCCAT
GTGGTGTGCGACCCGACCCGAACCCGCAAACTGCTGCTGAGCCGTCGTGAACTCGACAAGCTCGAGAGCCTGATTGCCCG
CCAGGGTTACACCGTCGTTCCCCTCGCCCTCTACTGGAAACAGTGCTGGGTCAAGGTCGAGATCGGCCTGGTGAAGGGCA
AGAAAGAGCACGACAAGCGCGAAGACACCAAGGCCCGCGAATGGGATCGGGAAAAAGCGCGCATCATGAAGAACAAGCAC
CGCGGTTGA

Protein sequence :
MSKKNSKNKAGSNTIALNRSARHEYFIEEKIEAGLSLQGWEVKSLRAGKANISEAYVIFRDGEAYLFGSSFLPLQAASSH
VVCDPTRTRKLLLSRRELDKLESLIARQGYTVVPLALYWKQCWVKVEIGLVKGKKEHDKREDTKAREWDREKARIMKNKH
RG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-46 64
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-24 45
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 8e-19 41