Gene Information

Name : cadB (AHA_1191)
Accession : YP_855732.1
Strain : Aeromonas hydrophila ATCC 7966
Genome accession: NC_008570
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 1293430 - 1294764 bp
Length : 1335 bp
Strand : +
Note : antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGTCCCTAGATACGAGCAAGAAGATCGGCCTTGTCGCCTGTACAGGTGTGGTGGCCGGCAACATGATGGGGAGCGGTAT
TGCACTGCTGCCCTCGGCCCTGGCCACCATAGGTTCCATCTCTGTGTTCAGCTGGGCCATCTGCCTGGTCGGCGCCATGG
GGCTGGCCTTCGTGTTTGCCCGCCTTGCCACCAAGAACCCGCAAGAGGGTGGCCCCATCGCCTACGCCGGCGAGATCTCT
CCGGTGTTCGGTTTCCAGACCGGCGTGCTCTACTACCACGCCAACTGGATCGGTAACCTGGCTATCGCCATCACCGGCGT
CTCCTACCTCTCCGTGTTCTTCCCCATTCTCAACAGCCCGATCCCGGCCGCCGCGGCCACCATCGCCGCCGTCTGGATCT
TCACCTTCGTCAACCTGCTTGGCGGCAGCTGGGTGAGCCGGCTCTGTACTTTGGGGCTGGTGCTGATCCTGTTGCCGGTA
GTGGGTACTGCCGTGATGGGCTGGGGCCATTTTGATGCCACCGTCTACAGCCAGAACTGGAACACCACCAGCGGCAGCGA
CCTGCATGCGGTCATCAGCGCCGTGCTGATCTGCCTCTGGTCCTTCGTGGGCGTCGAGTCCGCCGCCGTCTCTTCCGGCA
TGGTGAAGAACCCCAAGCGCACCGTACCGCTCGCCACCATGCTGGGTACCGGTATCGCGGGGATCATCTACATCCTCTCC
ACCCAGGTGATCAGCGGCATGTTCCCGGCCGGTGAAGTGGCTGCCTCCGGTGCGCCGTTTGCCATGGCCTCTTCCGCCAT
CTTCGGCAGCTGGTCTGCGCCGTTCGTCTCCGCCTTCACCGCGCTGGCCTGCTTCACCTCGCTGGGTTCCTGGATGATGC
TGGTGGGCGAGGCGGGCAAGCGTGCCGCCCACGACGGCAACTTCCCGAAAATCTACGGCGAAGTGGACAAGAACGGCGTC
GCCAAGAAGGGTCTGATCCTGGGCTCCCTCAAGATGACTGCGCTGATGGTCGGCCTGACCGCTTTCACCTCCCAGTCCGC
CCACGCCGCCGATCTCTTCAACGTGCTGACCACAGATGCGGTGCTGCTGACCATGCTGCCCTACTTCTACTCCAGCATTA
ACCTGATCCGTTTTGAAGGCATGACCTCCCGCAGCATCGGCGCCATGATCTTCTCCGGTGTCGCCTGCGTGTTCTGCCTG
GTGGCCCTGATGGGTGCCAAGGGTTCCAACCTCACCGCGACCTTCGTGGTGTCGCTCATCATCCTGATGTTCTACGCCAA
GAAACAGGGTCTGCGTCAGCACGACGCCCTGCTCAAAGAGCAGACCAGCCACTAA

Protein sequence :
MSLDTSKKIGLVACTGVVAGNMMGSGIALLPSALATIGSISVFSWAICLVGAMGLAFVFARLATKNPQEGGPIAYAGEIS
PVFGFQTGVLYYHANWIGNLAIAITGVSYLSVFFPILNSPIPAAAATIAAVWIFTFVNLLGGSWVSRLCTLGLVLILLPV
VGTAVMGWGHFDATVYSQNWNTTSGSDLHAVISAVLICLWSFVGVESAAVSSGMVKNPKRTVPLATMLGTGIAGIIYILS
TQVISGMFPAGEVAASGAPFAMASSAIFGSWSAPFVSAFTALACFTSLGSWMMLVGEAGKRAAHDGNFPKIYGEVDKNGV
AKKGLILGSLKMTALMVGLTAFTSQSAHAADLFNVLTTDAVLLTMLPYFYSSINLIRFEGMTSRSIGAMIFSGVACVFCL
VALMGAKGSNLTATFVVSLIILMFYAKKQGLRQHDALLKEQTSH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 2e-133 68
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 1e-133 68
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 7e-128 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB YP_855732.1 lysine/cadaverine antiporter VFG1671 Protein 4e-128 65