Gene Information

Name : glnA (APECO1_2592)
Accession : YP_859466.1
Strain : Escherichia coli APEC O1
Genome accession: NC_008563
Putative virulence/resistance : Virulence
Product : glutamine synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0174
EC number : 6.3.1.2
Position : 4374594 - 4376003 bp
Length : 1410 bp
Strand : -
Note : forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltra

DNA sequence :
ATGTCCGCTGAACACGTACTGACGATGCTGAACGAGCACGAAGTGAAGTTTGTTGATTTGCGCTTCACCGATACCAAAGG
TAAAGAACAGCACGTCACTATCCCTGCTCATCAGGTGAATGCCGAATTCTTCGAAGAAGGCAAAATGTTTGACGGCTCCT
CGATTGGCGGCTGGAAAGGCATTAACGAATCCGATATGGTGCTGATGCCAGACGCATCCACCGCAGTGATTGATCCGTTC
TTCGCCGATTCTACCCTGATTATCCGTTGCGACATCCTTGAACCTGGCACCCTGCAAGGCTATGACCGTGACCCGCGCTC
TATTGCGAAGCGCGCTGAAGATTACCTGCGTTCCACTGGCATTGCCGACACCGTACTGTTCGGGCCAGAACCTGAATTCT
TCCTGTTCGATGACATCCGTTTCGGATCGTCTATCTCCGGTTCCCACGTTGCTATCGACGATATCGAAGGTGCATGGAAC
TCCTCCACCCAATATGAAGGTGGTAACAAAGGTCACCGTCCGGCAGTGAAAGGCGGTTACTTCCCGGTTCCGCCGGTAGA
CTCAGCTCAGGATATTCGTTCTGAAATGTGTCTGGTGATGGAACAGATGGGTCTGGTAGTTGAAGCTCATCACCACGAAG
TCGCTACCGCAGGTCAGAACGAAGTGGCTACCCGCTTCAATACCATGACCAAAAAAGCTGACGAAATTCAGATCTACAAA
TATGTCGTGCACAACGTGGCGCACCGTTTCGGTAAGACCGCGACCTTTATGCCAAAACCGATGTTCGGTGATAACGGTTC
CGGTATGCACTGCCACATGTCGCTGTCTAAAAACGGCGTTAACCTGTTTGCTGGCGACAAATACGCAGGTCTGTCTGAAC
AGGCGCTGTACTACATTGGCGGCGTAATCAAACACGCGAAAGCGATTAACGCCCTGGCAAACCCGACCACCAACTCTTAC
AAGCGTCTGGTCCCGGGCTACGAAGCACCGGTGATGCTGGCTTACTCTGCGCGTAACCGTTCTGCGTCTATCCGTATTCC
GGTGGTTTCTTCTCCGAAAGCACGTCGTATCGAAGTACGTTTCCCGGACCCGGCGGCTAACCCGTACCTGTGCTTTGCTG
CCCTGCTGATGGCCGGTCTTGATGGCATCAAGAACAAGATCCATCCGGGCGAAGCCATGGACAAAAACCTGTATGACCTG
CCGCCAGAAGAAGCGAAAGAGATCCCACAGGTTGCAGGCTCTCTGGAAGAAGCACTGAACGAACTGGATCTGGACCGCGA
GTTCCTGAAAGCTGGTGGCGTGTTCACGGATGAAGCGATCGATGCGTACATCGCTCTGCGTCGCGAAGAAGATGACCGCG
TGCGTATGACTCCGCATCCGGTAGAGTTTGAGCTGTACTACAGCGTCTAA

Protein sequence :
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPF
FADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLSKNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSY
KRLVPGYEAPVMLAYSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDL
PPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 6e-103 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
glnA YP_859466.1 glutamine synthetase VFG1399 Protein 1e-116 51