Gene Information

Name : ribD (APECO1_1596)
Accession : YP_851588.1
Strain : Escherichia coli APEC O1
Genome accession: NC_008563
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 1.1.1.193
Position : 449288 - 450391 bp
Length : 1104 bp
Strand : +
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
GTGCAGGACGAGTATTACATGGCGCGGGCGCTAAAGCTGGCGCAACGAGGACGTTTTACCACGCATCCCAACCCGAATGT
CGGGTGCGTCATTGTCAAAGATGGCGAAATTGTCGGTGAAGGTTACCATCAACGCGCGGGTGAACCGCATGCCGAGGTAC
AGGCGTTGCGCATGGCCGGCGAAAAAGCCAAAGGCGCAACGGCGTATGTCACACTCGAACCCTGTAGCCATCATGGTCGT
ACGCCACCGTGTTGTGATGCATTAATTGCTGCGGGCGTGGCGCGCGTGGTTGCTGCAATGCAAGACCCCAATCCGCAGGT
CGCTGGACGTGGACTTTACCGTTTGCAACAGGCTGGCATTGACGTCAGCCACGGGCTGATGATGAGTGAAGCTGAGCAAT
TGAATAAAGGCTTTCTCAAGCGGATGCGCACCGGCTTTCCTTATATTCAGTTAAAACTTGGCGCATCGCTTGATGGTCGC
ACGGCGATGGCGAGTGGCGAAAGCCAGTGGATCACTTCACCTCAGGCGCGACGCGACGTACAACGACTGCGCGCGCAAAG
TCATGCCATTTTAACCAGCAGCGCCACGGTGCTGGCGGATGATCCAGCCTTAACAGTGCGTTGGTCTGAACTGGATGAAC
AAACTCAGGGGCTCTACCCGCAACAAAATCTCCGTCAGCCAGTACGTATTGTGATTGATAGCCAAAATCGCGTGACGCCG
GAACATCGCATTGTGCAGCAGCCCGGCGAAACCTGGTTCGCGCGTACGCAGGAAGATTCTCGTGAGTGGCCGGAAACGGT
GCGTACCTTGCTGATTCCAGAGCATAAAGGTCACCTGGATCTGGTTGTACTAATGATGCAACTGGGTAAACAGCAGATTA
ACAGCATCTGGGTGGAAGCGGGGCCAACGCTCGCTGGCGCATTGCTACAGGCGGGTTTAGTCGATGAGCTGATTGTCTAT
ATCGCACCTAAACTATTAGGCAACGACGCCCGTGGATTATGCACGCTGCCAGGGCTTGAGAAATTAGCCGACGCTCCCCA
ATTTAAATTCAAAGAGATACGTCATGTAGGCCCGGATGTTTGCCTGCATTTAGTGGGTGCATGA

Protein sequence :
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVQALRMAGEKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVAAMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQGLYPQQNLRQPVRIVIDSQNRVTP
EHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVY
IAPKLLGNDARGLCTLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 5e-65 48
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 5e-65 48