Gene Information

Name : nrdE (APECO1_3846)
Accession : YP_853851.1
Strain : Escherichia coli APEC O1
Genome accession: NC_008563
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 2973142 - 2975247 bp
Length : 2106 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGGATTATCACGCTCTGAATGCGATGCTTAACCTTTACGATAGCGCAGGTCGCATTCAGTTCGATAAAGACAGCCAGGC
CGTAGACGCCTTTATGACGACGCATGTGCGTCCGAACAGTGTGGCCTTCAGTAGCCAGCAGCAGCGCCTGAACTGGCTGG
TTAACGAAGGTTACTATGATGAAAGCGTCCTTAATCGCTACTCTCGCGATTTTGTCATTACGCTGTTTGCCCACGCGCAC
GCCAGCGGTTTTCGTTTCCAGACATTCCTCGGAGCATGGAAGTTTTACACCAGCTATACGTTGAAGACATTCGACGGTAA
GCGTTATCTGGAAGATTTTGCCGATCGCGTCACGATGGTGGCGCTGACGCTGGCACAAGGCGATGAAACACTGGCGACGC
AGCTCACTGATGAGATGCTGTCAGGACGCTTTCAGCCAGCCACGCCAACATTCCTCAACTGCGGTAAGCAGCAGCGCGGC
GAACTGGTTTCCTGTTTTCTGCTGCGTATTGAAGACAATATGGAGTCGATTGGCCGGGCAGTAAATTCCGCACTACAACT
GTCGAAACGCGGCGGCGGCGTAGCATTTTTGCTGTCGAATCTGCGGGAAGCGGGCGCGCCAATTAAACGTATTGAAAATC
AATCTTCTGGCGTGATTCCGGTGATGAAAATGCTGGAAGACGCATTTTCCTATGCCAACCAACTCGGCGCGCGTCAGGGG
GCTGGTGCAGTCTATTTACATGCTCATCATCCCGATATTCTGCGTTTTCTCGATACAAAACGGGAAAATGCCGACGAAAA
AATCCGCATTAAAACACTGTCGCTGGGCGTGGTGATCCCGGATATCACTTTCCATCTGGCAAAAGAGAATGCGCAGATGG
CGCTGTTTTCGCCCTATGACGTAGAGCGAGTTTATGGCAAGCCGTTTGCCGATGTCGCCATCAGTGAACACTATGACGAA
CTGGTTGCCGATGAACGCATCCGCAAAAAATACCTCAACGCCCGTGATTTCTTCCAGCGACTGGCAGAAATCCAGTTTGA
GTCTGGCTATCCGTACATCATGTATGAAGACACGGTTAACCGTGCTAACCCTATCGCCGGGCGCATAAATATGAGCAATC
TCTGCTCAGAAATTTTGCAGGTTAACAGCGCCTCAGAATATGACGAGAATCTCGACTATGCTCGTACAGGACATGATATT
TCCTGCAATCTAGGGTCGTTGAATATTGCCCACACCATGGATTCCCCCGACTTTGCCCGCACGGTAGAGACTGCCGTACG
CGGTTTAACGGCGGTGTCAGATATGAGTCATATCCGCAGCGTGCCGTCCATCGAAGCCGGAAATGCCGCCTCACACGCCA
TCGGTCTGGGGCAGATGAATTTACACGGTTATCTGGCACGAGAAGGCATCGCTTATGGGTCGCCGGAAGCACTGGATTTC
ACCAATCTCTATTTCTATACCATCACCTGGCACGCACTGCGTACCTCGATGTTGCTGGCGCGCGAACGCGGTGAAACCTT
CGCCGGGTTCAAACAGTCACGCTATGCCAGTGGTGAATATTTCAGCCAATATCTGCAAGGTAACTGGCAGCCGAAAACGG
CGAAAGTTGGCGAACTGTTTGCCCGTAGCGGTATTACGTTACCTACCCGTGAGATGTGGGCACAGCTGCGCGACGACGTG
ATGCGCTATGGTATCTACAACCAGAATCTCCAGGCGGTGCCGCCAACCGGTTCTATCTCTTATATCAACCATGCCACGTC
GAGTATTCATCCGATTGTGGCGAAAGTAGAGATACGCAAAGAGGGCAAAACAGGACGCGTTTACTACCCTGCCCCGTTTA
TGACTAACGAAAATCTGGCGCTGTATCAGGACGCTTACGAAATCGGCGCAGAAAAGATCATCGACACCTACGCGGAAGCG
ACTCGCCATGTCGATCAGGGGCTGTCGCTGACGCTGTTTTTCCCCGATACCGCCACCACTCGCGATATCAACAAAGCGCA
GATTTACGCCTGGCGCAAGGGTATCAAAACGCTCTATTACATTCGCCTGCGTCAGATGGCGCTGGAAGGCACTGAAATTG
AAGGCTGCGTCTCCTGTGCACTTTAA

Protein sequence :
MDYHALNAMLNLYDSAGRIQFDKDSQAVDAFMTTHVRPNSVAFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAH
ASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLATQLTDEMLSGRFQPATPTFLNCGKQQRG
ELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLGARQG
AGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISEHYDE
LVADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEYDENLDYARTGHDI
SCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDF
TNLYFYTITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFARSGITLPTREMWAQLRDDV
MRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEA
TRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 72