Gene Information

Name : topB (APECO1_832)
Accession : YP_852847.1
Strain : Escherichia coli APEC O1
Genome accession: NC_008563
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1858478 - 1860487 bp
Length : 2010 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
GTGAACTTGTTTCCGCCCGTGGTGGTCGTGCCATGGTTGAGATTCGTTAAGTCGATGCGGTTGTTTATTGCCGAAAAACC
GAGTCTGGCGCGCGCCATTGCTGATGTCCTGCCTAAACCGCACCGGAAAGGCGATGGCTTTATCGAATGCGGTAATGGTC
AGGTGGTGACCTGGTGTATCGGTCACCTGCTTGAGCAGGCGCAGCCAGACGCCTACGACAGCCGCTATGCGCGCTGGAAT
CTTGCGGATTTGCCGATTGTCCCGGAAAAGTGGCAATTACAGCCCCGACCCTCCGTGACTAAACAACTTAATGTCATCAA
ACGCTTCCTGCATGAAGCCAGCGAAATCGTTCACGCCGGAGACCCGGATCGCGAAGGGCAACTGCTGGTGGATGAAGTGC
TGGACTACCTGCAACTGGCACCGGAAAAGCGCCAGCAGATACAGCGTTGTTTGATAAACGACCTGAACCCGCAGGCGGTT
GAGCGGGCGATCGATCGTCTTCGCTCCAATAGCGAGTTTGTACCGCTGTGCGTTTCTGCACTGGCGCGGGCGCGGGCTGA
CTGGCTGTACGGCATTAATATGACCCGTGCGTATACCATTCTCGGTCGCAATGCCGGTTATCAGGGCGTGCTTTCCGTGG
GACGCGTGCAGACGCCCGTACTCGGACTGGTGGTGCGCCGCGACGAAGAGATTGAAAACTTCGTGGCGAAAGACTTCTTT
GAAGTCAAAGCACATATCGTGACACCTGCCGATGAGCGGTTTACCGCTATCTGGCAACCGAGCGAAGCGTGTGAACCGTA
CCAGGATGAAGAAGGGCGCTTGTTACATCGTCCACTGGCGGAGCATGTGGTTAACCGCATTAGTGGTCAACCAGCTATTG
TCACCAGCTATAACGATAAACGGGAATCAGAATCCGCGCCGCTGCCTTTTTCGCTTTCGGCGTTGCAGATTGAAGCGGCT
AAACGTTTTGGTCTGAGCGCGCAGAACGTGCTTGATATCTGCCAGAAGCTGTACGAAACGCACAAGCTAATCACTTATCC
GCGTTCCGATTGCCGCTATTTGCCAGAAGAACATTTTGCCGGACGCCACGCGGTGATGAATGCTATCAGCGTTCATGCAC
CGGATCTGTTGCCGCAGCCAGTGGTAGATCCAGATATACGCAACCGCTGTTGGGATGACAAAAAGGTCGATGCGCACCAC
GCCATCATTCCGACCGCACGGAGTTCTGCGATCAACCTGACGGAGAACGAAGCGAAGGTCTATAACCTGATTGCCCGTCA
GTACTTGATGCAGTTCTGCCCGGATGCGGTGTTCCGCAAGTGTGTTATCGAACTGGACATTGCCAAAGGCAAATTTGTCG
CTAAAGCCCGTTTTCTTGCTGAAGCAGGCTGGCGCACGCTGTTAGGCAGCAAAGAGCGCGATGAAGAAAACGACGGCACG
CCGCTGCCTGTGGTGGCGAAAGGCGATGAATTGTTGTGCGAAAAAGGCGAAGTGGTAGAGCGGCAAACCCAGCCGCCACG
CCATTTTACCGATGCAACACTGCTTTCGGCGATGACCGGGATCGCACGCTTTGTGCAGGACAAAGATCTGAAAAAGATCC
TTCGTGCGACCGATGGTCTGGGGACAGAAGCAACGCGTGCCGGGATTATTGAATTGTTGTTCAAGCGGGGTTTCCTGACC
AAAAAAGGGCGCTATATCCACTCCACCGACGCCGGAAAAGCGCTATTCCATTCGCTGCCAGAAATGGCGACGCGACCGGA
CATGACCGCGCACTGGGAATCGGTGCTGACGCAAATCAGCGAAAAGCAGTGTCGCTATCAGGACTTTATGCAGCCGCTGG
TGGGGACATTGTACCAGTTGATTGATCAGGCAAAGCGCACGTCGGTAAGGCAGTTTCGGGGAATAATGGCTCCCGGCGGT
AGAGAAGGGAAGAAAAAGGATTCGCCACGCAAGAGAGCGCCGAAAAAAAGCCCGCCATCAGAAGAGGCGGGCAATGGAGT
GATAACATAA

Protein sequence :
MNLFPPVVVVPWLRFVKSMRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWN
LADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQIQRCLINDLNPQAV
ERAIDRLRSNSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFF
EVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAA
KRFGLSAQNVLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHH
AIIPTARSSAINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGT
PLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLT
KKGRYIHSTDAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTSVRQFRGIMAPGG
REGKKKDSPRKRAPKKSPPSEEAGNGVIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-100 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-109 41