Gene Information

Name : ycgO (APECO1_303)
Accession : YP_852318.1
Strain : Escherichia coli APEC O1
Genome accession: NC_008563
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1251277 - 1252887 bp
Length : 1611 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGCTGGCGGGGGTTGATGGCGTCGGCGGTATCCCGTTTGATAATTATCCCTTCGCCTACATGGTAAGTAACCTGGCGCT
GGCGATTATTTTGCTCGACGGCGGGATGCGCACTCAGGCCAGTTCCTTTCGTGTGGCGTTAGGACCGGCACTGTCGCTGG
CGACGCTGGGCGTGCTTATCACCTCTGGTTTAACCGGCATGATGGCGGCGTGGCTGTTTAATCTTGATTTGATTGAAGGA
TTATTAATCGGCGCTATCGTCGGCTCCACCGATGCTGCAGCGGTCTTTTCTCTGCTGGGTGGTAAGGGGCTTAACGAACG
TGTTGGCTCGACGCTGGAAATTGAATCCGGCAGTAATGATCCAATGGCGGTCTTTCTGACGATTACCCTGATTGCGATGA
TCCAGCAGCATGAAAGCAGTGTCAGCTGGATGTTCGTGGTCGATATTCTGCAGCAATTTGGCCTCGGGATTGTCATCGGG
CTTGGCGGTGGTTATTTACTGCTGCAAATGATTAATCGCATCGCCCTGCCCGCCGGATTATATCCATTGCTGGCATTAAG
CGGCGGTATTTTAATTTTTGCTTTAACCACGGCGCTGGAAGGCAGCGGTATTCTGGCTGTTTATCTGTGCGGTTTTCTGC
TGGGTAATCGGCCGATTCGCAACCGCTACGGCATCCTGCAAAATTTCGACGGCCTCGCCTGGCTGGCGCAAATCGCCATG
TTCCTGGTGCTGGGGCTATTGGTTAACCCAAGCGATCTGCTGCCTATTGCCATTCCGGCGCTCATTTTGTCCGCATGGAT
GATTTTCTTCGCCCGTCCTCTTTCGGTATTTGCCGGATTGCTACCGTTCCGTGGCTTCAATCTGCGTGAGCGCGTGTTTA
TCAGCTGGGTAGGATTACGCGGCGCGGTGCCGATTATTCTGGCTGTGTTCCCGATGATGGCGGGGCTGGAGAATGCGCGA
CTGTTCTTTAATGTCGCCTTCTTTGTGGTCCTGGTTTCACTGCTATTGCAGGGAACATCACTCTCGTGGGCGGCGAAAAA
AGCCAAAGTGGTCGTTCCGCCAGTGGGACGTCCGGTGTCACGCGTTGGCCTGGATATTCATCCGGAAAATCCGTGGGAGC
AGTTTGTTTATCAATTGAGTGCCGATAAATGGTGCGTGGGCGCGGCACTGCGTGATTTGCATATGCCAAAAGAGACGCGT
ATTGCGGCACTGTTTCGTGATAACCAGTTGCTTCATCCCACCGGCAGCACCCGACTGCGCGAAGGCGATGTGTTGTGTGT
AATTGGTCGGGAACGCGATCTCCCGGCGCTCGGTAAACTGTTCAGCCAGTCGCCGCCGGTCGCGCTGGATCAACGCTTCT
TTGGTGACTTCATTCTCGAAGCCAGCGCCAAATATGCTGATGTGGCGCTGATATATGGCCTGGAAGACGGGCGAGAATAT
CGCGATAAGCAGCAAACGCTGGGTGAAATCGTCCAGCAGTTGTTAGGCGCAGCACCGGTTGTCGGTGACCAGGTAGAGTT
TGCCGGGATGATCTGGACGGTGGCCGAGAAAGAAGATAATGAAGTGTTGAAGATTGGTGTTCGGGTAGCGGAGGAAGAAG
CCGAATCTTAA

Protein sequence :
MLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEG
LLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIG
LGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAM
FLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENAR
LFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETR
IAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREY
RDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 99
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 99