Gene Information

Name : thyA (lwe1894)
Accession : YP_850091.1
Strain : Listeria welshimeri SLCC5334
Genome accession: NC_008555
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1923485 - 1924429 bp
Length : 945 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATATTTGGATTTAGAAAAGTACGTTTTAGAGAATGGAACACAAAAAGGAGATCGCACTGGGACTGGAACAAT
CAGCACATTTGGTTATCAAATGCGTTTTGATTTGCAAGAGGGCTTTCCTATCATGACAACCAAACGTGTACCATTTAAAC
TTGTCGTAAGTGAGCTATTATGGTTTTTACATGGAGATACAAATATTCGCTACCTTTTACAGCATAACAATAATATTTGG
AATGAATGGGCTTTTGAGCGTTTTGTGAAAAGTGCTGATTATAAAGGCGAAGATATGACTGATTTTGGCCTAAGAGCAGA
ACGTGATCCGGCGTTTAAAGAAGTGTATCAAGCGGAAATGGAACAGTTTAAAACGCGCATTTTAGAAGATGAAGGATTTG
CGAATAAATACGGTGAATTAGGTAATATTTATGGAAAACAATGGCGCGAGTGGAAAACTTCTCAAGGAGAAACGATTGAC
CAGTTAGCAGATGTGATTGAAATGATTAAAACAAACCCAAATTCTCGCCGCTTAATTGTGTCTGCTTGGAATCCAGAAGA
TATTCCGAATATGGCTTTACCACCATGCCATTCCTTGTTCCAATTTTATGTAGCGGATGGGAAATTATCCTGCCAATTGT
ATCAGCGTAGTGCAGATATTTTTCTAGGGGTGCCATTTAATATTGCAAGTTATGCACTTCTGACACATCTTATTGCTCGA
GAAGTGGGACTTGATGTGGGCGAATTCATTCATACAATGGGAGATGCACATCTTTATAATAATCATATTGAGCAAGTGAA
AGAACAATTATCGAGAACACCGCATGCACTTCCAAAATTAGTGCTTTCAGATAAACCTACAACCATTTTTGATTTTGATG
TAGCGGATATTTCCCTCGATGGTTATCATCCAGATCCAGCAATTAAAGCACCGATTTCAGTATAA

Protein sequence :
MKQYLDLEKYVLENGTQKGDRTGTGTISTFGYQMRFDLQEGFPIMTTKRVPFKLVVSELLWFLHGDTNIRYLLQHNNNIW
NEWAFERFVKSADYKGEDMTDFGLRAERDPAFKEVYQAEMEQFKTRILEDEGFANKYGELGNIYGKQWREWKTSQGETID
QLADVIEMIKTNPNSRRLIVSAWNPEDIPNMALPPCHSLFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAR
EVGLDVGEFIHTMGDAHLYNNHIEQVKEQLSRTPHALPKLVLSDKPTTIFDFDVADISLDGYHPDPAIKAPISV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-101 64