Gene Information

Name : guaA (lwe1071)
Accession : YP_849268.1
Strain : Listeria welshimeri SLCC5334
Genome accession: NC_008555
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1091959 - 1093515 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGTTTAAAATTATGAAAGACTTTACCGAGCAAGAGAAAATTATCGTTCTAGATTTTGGTAGTCAGTACAATCAACTAAT
TACGCGCCGCATTCGTGAATTCGGTGTGTATAGTGAATTACATCCGCATACTATTACAGTTGAAGAAATGAAAGCACTAA
ATCCAACGGGGATTATTTTTTCAGGAGGACCTAACAGTGTGTATGACAAAGATGCTTTTCGCGCTGACGAAAGAATCTTT
GACATGGGAATTCCGATTTTAGGAATTTGTTACGGCATGCAATTAATGACAACCCATTTCGATGGTAAAGTAGAACGTGC
AAAAGATCGCGAATACGGGAAAGCGGATATTCATGTGGAAAATCCGAGCCGTTTATTTGCAGGACTTCCAACAGATCAAG
TTGTCTGGATGAGTCACGGCGATTTAGTCGTTGAGGAACCAGCTGGTTTTGAAGTAACAGCAACTAGTCCATCTTGCCCA
ATTGCTGGAATTGCAGACGAAGAACGGTTACTATACGGCGTGCAATTCCACCCAGAAGTACGTCACTCTGTTTATGGAAA
CGAATTACTGAAGAATTTTGCATTAAACGTATGTGGATGTAAAGGCGACTGGACAATGGAAAACTTTAGTGAAGTAGAAA
TCGCTAAAATCCAAGAAATCGTTGGTGATAAAAAAGTCTTGCTTGCACTTTCTGGCGGTGTTGATTCTTCCGTTGTTGGT
GTGTTAATTCATAAAGCAATTGGCGACCAACTAACATGTATTTTCGTAGACCACGGCCTTCTTCGTAAAGGGGAAGCTGA
CCAAGTAATGGCGACGTTACAAGGCGAATTCAACATGAACATCATCAAAGTAGATGCGAAAAAACGTTTCATGGACAAAC
TAGCTGGCGTTTCTGACCCAGAACAAAAACGTAAAATCATCGGAAACGAATTCATTTACGTATTCGACGATGAAGCCAAC
AAACTAGATGGCGTAGAATTCCTTGCACAAGGAACACTTTACACAGACATCATCGAAAGTGGTACAGCAACTGCCCAAAC
AATCAAGTCGCACCACAATGTCGGCGGTTTACCAGAAGATATGCAATTTAAACTAATCGAACCATTAAATACACTCTTCA
AAGATGAAGTTCGAGCACTAGGAACTGAACTTGGCATGCCTGACGCAATCGTTTGGCGCCAACCATTCCCAGGCCCAGGC
CTAGGAATCCGCGTCCTTGGCGAAATCACGGAAGAAAAATTAGAGATTGTCCGCGATTCTGATTACATCCTGCGCGAAGA
AATCAAAAAAGCCGGCCTAGAACGCGAAATCTGGCAATATTTCACAGCACTTCCAAACATCCGTAGCGTTGGTGTTATGG
GTGATGGCAGAACGTATGACCATACTGTGGTTGTTCGTGCGGTGACGAGTATTGACGGTATGACAGCTGATTGGGCACGT
ATTCCTTGGGATGTACTGGAGAAGATTTCAGTGCGGATTGTGAATGAAGTGGATCATGTGAATCGTGTTGTTTATGATAT
TACGAGTAAGCCACCAGCTACGGTTGAGTGGGAATAA

Protein sequence :
MFKIMKDFTEQEKIIVLDFGSQYNQLITRRIREFGVYSELHPHTITVEEMKALNPTGIIFSGGPNSVYDKDAFRADERIF
DMGIPILGICYGMQLMTTHFDGKVERAKDREYGKADIHVENPSRLFAGLPTDQVVWMSHGDLVVEEPAGFEVTATSPSCP
IAGIADEERLLYGVQFHPEVRHSVYGNELLKNFALNVCGCKGDWTMENFSEVEIAKIQEIVGDKKVLLALSGGVDSSVVG
VLIHKAIGDQLTCIFVDHGLLRKGEADQVMATLQGEFNMNIIKVDAKKRFMDKLAGVSDPEQKRKIIGNEFIYVFDDEAN
KLDGVEFLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTELGMPDAIVWRQPFPGPG
LGIRVLGEITEEKLEIVRDSDYILREEIKKAGLEREIWQYFTALPNIRSVGVMGDGRTYDHTVVVRAVTSIDGMTADWAR
IPWDVLEKISVRIVNEVDHVNRVVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 75
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 75
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 75
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-128 53