Gene Information

Name : smpB (Sfum_0771)
Accession : YP_844904.1
Strain : Syntrophobacter fumaroxidans MPOB
Genome accession: NC_008554
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 946554 - 947039 bp
Length : 486 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACCAAGAACAAGCCCTCGACCGCTGAAAAGACCCGACTGATCTGCCAGAACAAGAAGGCATATCACGACTACGATAT
CCTGGAGAAATTCGAGGCGGGAATCGTCTTGCTGGGCACCGAGGTGAAGTCGCTGCGGGAAGGCAGGGCGAACCTCAAGG
ACAGTTACGCCCGGGTGAGGAAGGGGGAGGTTTTCCTCCAGGGGCTTCACATCAGTCCCTACACTCACGCCTCCTACAAC
AACCATGAACCCGAACGGGTTCGCAAGCTCCTGCTCCATGCCCACGAGATCAAGAGACTGACCGGCAAGACCCAGGAGCG
GGGCCTCGCGCTGATTCCTTTGAAACTCTACTTCAGCAAGGGAAAAGTGAAGGTGGAGCTTGCCCTGGCACAGGGCAAGA
AGCTCTACGACAAGAGGGAGAGCATCAAACGGAAAGAAGAGAACCGGGAGCTCGACCGCCTGAGAAAACGCCGCAGGCAG
GAATGA

Protein sequence :
MTKNKPSTAEKTRLICQNKKAYHDYDILEKFEAGIVLLGTEVKSLREGRANLKDSYARVRKGEVFLQGLHISPYTHASYN
NHEPERVRKLLLHAHEIKRLTGKTQERGLALIPLKLYFSKGKVKVELALAQGKKLYDKRESIKRKEENRELDRLRKRRRQ
E

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-29 55
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-34 53
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 8e-25 46