Gene Information

Name : Sfum_3773 (Sfum_3773)
Accession : YP_847877.1
Strain : Syntrophobacter fumaroxidans MPOB
Genome accession: NC_008554
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 4616082 - 4618295 bp
Length : 2214 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: mag:am

DNA sequence :
ATGGAAAGGATGGCCTTTCGGATCAGGGGCATGTGCTGCGGGGACGAGATCTCCGTTCTGAAGAGGCAGGTAGGGCCTCT
GGTCGGCGGCGAGCTGAACCTGTCCTTCGACTTGTTGAACGGCAAGATGACGGTGGTGTCCTCCGGCCCCCCCATACGCG
CGGAGGAGATCACGGCGGTGGTGGCCGCGACGGGGATGCAGGCCGTTCCATGGGTCGATTTCTGTTCGGGCGGCGTGTGC
GCGGTCGAGGAAGGCCTGTGGCGGCGCCACGGCCGCCTTCTGCTGTGCTGCGCCTCCGGTCTGTTGATCGTCGCGGGATT
CCTCCTTCACGTTTTCCAGAACGGGAGCTTCCTCGAGGCGCTGGCGGGCGGAGAACACGCCGGTCGGCCGTTTCCCCCGG
GAACCGTCATGCTCTACGCCTGCGCCATCGTCGCCGGCGGCTGGAATATCGCGCCCAGAGCCTTCTTTGCCGCAAGAAAT
CTTCAACCCGACATGAACCTGCTGATGGCCGTCGCGGTTGTCGGCGCCATATGGATCGGCCAGTGGACCGAAGCGGCGTC
CGTTACCTTTCTTTTCTCGCTGGCCCTGCTGCTCGAATCCTGGAGCGTCGGGCGCGCCCGCAACGCCATCCGCGCACTCA
CGGACATTTCACCCCGGACGGCCCGGTTCATCTGCCCCACGGACGGAGATATCGAAGAAAAACCGGTGGACGACGTCCCG
GTGGGCGCCACCGTTCTGGTGCGCCCGGGCGAAAAGATTCCCCTGGACGGCACCGTCACGGCGGGTGCCTCATGGGTCGA
CGAAGCGCCCATTACGGGCGAATCCCTCCCGGTGGAAAAGCGAATGGGAGACCCCGTATTTGCGGGGACCGTCAATGGCG
AGGGCGCGATCGAGTTCCGCGCGACGCGACCATCCGGCGACACCACTCTGGCACGCATCATCCGGATGGTCGAGGAAGGC
CAGGCCCGTCGCGCGCCCGCCGAACAGTGGGTCGAGCGGTTCGCACGGTTCTACACGCCCGCCATGATGATCCTGGCGGG
ACTGATCGCCGTGGCCCCCCCGCTGGTGTTGGGAGGCGATTGGACCGGGTGGTTCTACCAGGCCCTTGTCATCCTGGTGA
TCGCCTGTCCCTGCTCCCTGGTCATTTCAACCCCGGTGAGCGTCGTCTCCGGGCTGACCGCCGCCGCCCGCCATGGAGTC
CTGATCAAAGGCGGAGCTTTCCTCGAGGCTCCCGCGCACCTGCGTTCCATCGCCTTCGACAAGACCGGGACTCTGACGCG
GGGAGAACCCCGCATTCAGGAAATCATCCCGATGGACGACCACACCGAGAGCGGTCTGCTGTTGAATGCCGCCGCCCTCG
AATCGCACAGCACTCACCCCCTTGCGCGAGCCATTCTGAACGCGGCGCAGGCCAGGGGCATCGAGTACACGCCGGCCCGG
GACTTCACGATTCTTCCCGGCATGGGAGCCAGAGGGGTGATCGACGGCAGGCCATACTGGATCGGCAGTCATCGGATGCT
GGAAAGCCTCGAGCGGGAAAGCCCGCTGTTCCATGAAATGGCCTGCCGCCTCGAAGACGCGGGACATTCACTGGTGGCCA
TGTGGTGTGACGATCACATCTGCGGCGTGATGAGCGTGGCCGACATGGTGAGACCGGAGGCCGGGGAGGTCATCCGGGAA
TTGAAGTCCCTCGGTGTCCGCCGGGTCGTCATGATCACCGGCGACAACCACCGGACCGCCGCACAGGCGGCCCGTGCGAT
CGGCGTCGATGAATTCCATTCGGAATTGCTGCCGGAAGACAAGGTTGAGCTCGTGTCGAAAATGGAGCAGGAATCCGGCC
CCACCGCCATGGTGGGCGACGGAGTGAACGACGCGCCCGCCATGACCGCCTCCTCGGTATCCATCGCCATGGGCGCCATG
GGGTCCGACGCGGCCGTCGAGACCGCCGACATCGCCCTCATGTCCGACGACCTCACCCGACTTCCGTGGCTGGTCCGGCA
CTCCCGCAGGACCCTGGGGATCATCAAATCGAACATCGCCTTCTCCCTCGGGGTCAAGGCGCTCTTCGTGGTCCTGTCCG
TCATGGGACTGGCCAACCTCTGGGGGGCCATCGCGGCCGACATGGGTGCATCGCTCCTGGTGATTTTCAACGGGCTGCGG
CTGCTCGGCGATACCGTCCCCCGCTCGCCCGCGCTCACCGGAACAGCGGCATAG

Protein sequence :
MERMAFRIRGMCCGDEISVLKRQVGPLVGGELNLSFDLLNGKMTVVSSGPPIRAEEITAVVAATGMQAVPWVDFCSGGVC
AVEEGLWRRHGRLLLCCASGLLIVAGFLLHVFQNGSFLEALAGGEHAGRPFPPGTVMLYACAIVAGGWNIAPRAFFAARN
LQPDMNLLMAVAVVGAIWIGQWTEAASVTFLFSLALLLESWSVGRARNAIRALTDISPRTARFICPTDGDIEEKPVDDVP
VGATVLVRPGEKIPLDGTVTAGASWVDEAPITGESLPVEKRMGDPVFAGTVNGEGAIEFRATRPSGDTTLARIIRMVEEG
QARRAPAEQWVERFARFYTPAMMILAGLIAVAPPLVLGGDWTGWFYQALVILVIACPCSLVISTPVSVVSGLTAAARHGV
LIKGGAFLEAPAHLRSIAFDKTGTLTRGEPRIQEIIPMDDHTESGLLLNAAALESHSTHPLARAILNAAQARGIEYTPAR
DFTILPGMGARGVIDGRPYWIGSHRMLESLERESPLFHEMACRLEDAGHSLVAMWCDDHICGVMSVADMVRPEAGEVIRE
LKSLGVRRVVMITGDNHRTAAQAARAIGVDEFHSELLPEDKVELVSKMEQESGPTAMVGDGVNDAPAMTASSVSIAMGAM
GSDAAVETADIALMSDDLTRLPWLVRHSRRTLGIIKSNIAFSLGVKALFVVLSVMGLANLWGAIAADMGASLLVIFNGLR
LLGDTVPRSPALTGTAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 4e-130 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-139 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-139 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfum_3773 YP_847877.1 heavy metal translocating P-type ATPase BAC0298 Protein 1e-113 50
Sfum_3773 YP_847877.1 heavy metal translocating P-type ATPase BAC0461 Protein 2e-87 42
Sfum_3773 YP_847877.1 heavy metal translocating P-type ATPase BAC0100 Protein 3e-68 42