Gene Information

Name : Sfum_2670 (Sfum_2670)
Accession : YP_846783.1
Strain : Syntrophobacter fumaroxidans MPOB
Genome accession: NC_008554
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3300753 - 3301955 bp
Length : 1203 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mma:MM3085 methionine-gamma-lyase

DNA sequence :
ATGATGAAAGACGACGAACGCCTCCGTCGGATGGGGAAACACACGAAGGCCATCCATGGCGGCGGCCTCGAGAAGAAGGT
TTACGGGGAGATTTCGGTTCCCATTTTCCAGACCTCCACGTTCGGCTTCCCGAGCGCCGCGGAAGGGGCCGCTCGTTTCG
CGGGAGAGAGTGACGGCTACATCTACACCCGGCTGAACAACCCGACGGCGAACGCGCTGGAAGAAGCCATGACCCTGCTG
GAAGGCGGATTTGCCGCCATCGCCTCCTCCACCGGCATGGCCGCCGTCACCACGACGCTGCTCACGTTCCTTAGCCAGGG
AGACCACGTCGTGGCCACCGACTCGATCTACGGGGCATCCCGGATGGCCCTGCAGTTCGAATTTGCCCGGTTCGGCATTG
GGGCGACCTTTGTGGACAGCTCTTCGACAGCCAACATCGAGCGTGCGATTGGCCGAAACACGAAGGTGATCTTTTTGGAA
ACGCCCACCAATCCGACCATGGCCGTTTCCGATATCCGTGCGGCGGCGGAACTGGCCCGCGCCCGGGGCGCCATCCTCGT
AGTGGACAACACGTTCGCCGGTCCGTATCTCCAGCGCCCCCTGGAACTGGGCGCGGACATCGTCGTGGAAAGCCTCACCA
AGTTCATCAACGGCCACAGTGATGTCCTGGGCGGTATGGTCGTGACCCGGAATGAAGAACTCCACGCGCAGATCAAGAGG
ATGTTCACCCTGTTTGGAGGCACCATCGATCCCCATCAGGCATGGCTCATCCTGCGCGGCCTGAAAACCCTGCCGTTGAG
GGTGGAAAAGGCGCAGGACAATGCCGGCCGGCTTGCCCGGTTCCTCAGCGGGCATCCGAAGGTGACCTGGCTGCGCTACC
CTGGCCTGCCGGATCATCCGCAACACGAGGTTGCGAGGCGACAAATGGAAGGGTTCGGCTCCATGATGTCTTTTGGGGTG
AAAAACGGCCTGGAGGGCGGGATCACACTGATGAACGCCGTACACCTGATCACGCTCGCGGTTTCCCTCGGCGGGATCGA
CTCGCTCATCGAACATCCCGCGTCGATGACTCACGCCGCCATTCCCAGGGAGGAACGGGAGCGGGCCGGAATTCGTGACG
AGCTGGTGCGCCTCTCGGTCGGGTGCGAAGACTTTGAGGATCTGCGCGCGGACCTTGAGCACGCGCTGAGTTGCATTCCC
TGA

Protein sequence :
MMKDDERLRRMGKHTKAIHGGGLEKKVYGEISVPIFQTSTFGFPSAAEGAARFAGESDGYIYTRLNNPTANALEEAMTLL
EGGFAAIASSTGMAAVTTTLLTFLSQGDHVVATDSIYGASRMALQFEFARFGIGATFVDSSSTANIERAIGRNTKVIFLE
TPTNPTMAVSDIRAAAELARARGAILVVDNTFAGPYLQRPLELGADIVVESLTKFINGHSDVLGGMVVTRNEELHAQIKR
MFTLFGGTIDPHQAWLILRGLKTLPLRVEKAQDNAGRLARFLSGHPKVTWLRYPGLPDHPQHEVARRQMEGFGSMMSFGV
KNGLEGGITLMNAVHLITLAVSLGGIDSLIEHPASMTHAAIPREERERAGIRDELVRLSVGCEDFEDLRADLEHALSCIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-62 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-63 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-62 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfum_2670 YP_846783.1 cystathionine gamma-synthase BAC0207 Protein 3e-70 46