Gene Information

Name : Bcen2424_3659 (Bcen2424_3659)
Accession : YP_837290.1
Strain :
Genome accession: NC_008543
Putative virulence/resistance : Resistance
Product : Bcr/CflA subfamily drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 505935 - 507134 bp
Length : 1200 bp
Strand : +
Note : TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bcn:Bcen_4704 drug resistance transporter Bcr/CflA subfamily

DNA sequence :
ATGCCTGATCAAACCCGAACCACGCCCGCATGGGCTTACTCGCTGCCGTCGGCCTTGCTGCTGATGGCCCCTTTCGATCT
CCTCGCGTCGCTGGCGATGGACGTGTATCTGCCGGTGGTTCCGGAGATGCCGTCGGCGCTGCACACGTCGCCCGCCATGG
TGCAACTGACGCTGAGCGTCTACATGGTCGTCCTCGGCCTGGGCCAGTTGATGTTCGGCCCGCTGTCGGACCGGCTCGGA
CGTCGACCCGTGCTCCTGGGCGGTGCGCTACTGTTCTCGGTGGCTTCGCTGGCGCTTGCAATGGCGGGCAGCGGCGGCGT
GTTCGTCGCATTGCGCCTGCTGCAGGCGCTGGGCGCGTCGGCAGCGCTCGTGGCGACCTTTGCAACGGTGCGCGACGTGT
ATGCCGACCGTCCGGAAGGCAGCACCCTCTACAGCCAGTTCGGGGCGATCCTCGCGTTCGTCCCGGCGCTCGGGCCGATG
CTTGGCGCAGGCATTGCGCACGGTTTCGGATGGCGCGCGATCTTCATGACCCTCGGCGGCGCCGGATGTCTGGCGTTCTA
CCGCGCGTTGTCGCGTTGGCACGAAACCCGGCAGCAGGCCGGCGGCAAGCCGCGGCAATCCGCCGTATCGATCCTGCGCA
GTCCTTCTTTCCTCGTCTATTCGCTCGGTTTCGGCACGTCCATGGGCGCTTTTTTCGTGTTCTTTTCGATTGCGCCGCGT
GTGCTGGTCGGACAGGCCGGCTATTCCCGCACCGAATTCAGCGTGGCGTTTGCCACCGTCGCGATCGTGATGATCGGTGC
CGCGCGCTTTGCGCGATGGTTCGTGTCGAACTGGGGGGGGCCGGGCTGTTTCGTGCGCGGCGCCGGTGTCATGATGGCCG
GCGCAACCGCGCTGGCGGCGTGCACGGCCCTGATGGCGCCGTCATTCGTCTCGTTCGTGATGCCGATGTGGATCGTCGCG
ATCGGCATCGTGCTGATGTCGTCGGTGACGGCGAACGGCGCGCTTCGGGATTTCGACGACGCGGCGGGGACGGCGGTCGC
GTTGTATTACTGCGTGCAGAGCCTGATCGTCGGCGGGGCCGGCACGTTCGTGACGCTGGTGCTGCCCGGCGATACGCCGT
GGCCGCTGGCGGCGTTTTGTTTCGTCGCGCCGACGGCATGCGTCCTCGCGCTCGCCGCATTGAAGCGTACGCGCGGATGA

Protein sequence :
MPDQTRTTPAWAYSLPSALLLMAPFDLLASLAMDVYLPVVPEMPSALHTSPAMVQLTLSVYMVVLGLGQLMFGPLSDRLG
RRPVLLGGALLFSVASLALAMAGSGGVFVALRLLQALGASAALVATFATVRDVYADRPEGSTLYSQFGAILAFVPALGPM
LGAGIAHGFGWRAIFMTLGGAGCLAFYRALSRWHETRQQAGGKPRQSAVSILRSPSFLVYSLGFGTSMGAFFVFFSIAPR
VLVGQAGYSRTEFSVAFATVAIVMIGAARFARWFVSNWGGPGCFVRGAGVMMAGATALAACTALMAPSFVSFVMPMWIVA
IGIVLMSSVTANGALRDFDDAAGTAVALYYCVQSLIVGGAGTFVTLVLPGDTPWPLAAFCFVAPTACVLALAALKRTRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 1e-92 60
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-94 59
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-94 59
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-94 59
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 1e-94 58
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 1e-94 58
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 2e-70 49
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 3e-70 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcen2424_3659 YP_837290.1 Bcr/CflA subfamily drug resistance transporter DQ522237.1.gene4.p01 Protein 1e-70 49
Bcen2424_3659 YP_837290.1 Bcr/CflA subfamily drug resistance transporter NC_010410.6003586.p0 Protein 1e-70 49
Bcen2424_3659 YP_837290.1 Bcr/CflA subfamily drug resistance transporter AF294653.1.gene4.p01 Protein 1e-70 49
Bcen2424_3659 YP_837290.1 Bcr/CflA subfamily drug resistance transporter DQ984668.gene.p01 Protein 1e-70 49
Bcen2424_3659 YP_837290.1 Bcr/CflA subfamily drug resistance transporter AF156486.gene.p01 Protein 6e-69 48