Gene Information

Name : Bcen2424_5000 (Bcen2424_5000)
Accession : YP_838627.1
Strain :
Genome accession: NC_008543
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase/ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2019709 - 2021361 bp
Length : 1653 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: bcn:Bcen_3367 AMP-dependent synthetase and ligase

DNA sequence : 
ATGCAATCCTCCCCTTCCTCCCTGGCGGCGGCCGTGCCGGCCGACGCGCCCGACTGGCCCGACGACTTCGCGCGCCGCTA
CCGCGACGCCGGCTACTGGCAGGACACGACGTTCTTCGACGCGCTCGATGCGTGCGCGGAACGCCATCCCGACGCGCTCG
CCGTCGTCGACGGCACGCTGCGGCTGCGCTATCGCGATCTGCTCGCGCGCATTCGCCGCCTCGCGGGCGGCCTCGCGCGC
CTCGGCCTGGTGCGCGGCGACGCTGTCGTCGTCCAGTTGCCGAACGGCGCGCGCTTCATCGAGACGTGCTTCGCGCTGTT
CCAGCTCGGCGTGCGGCCGGTGCTCGCGCTGCCCGCGCACCGTCACTACGAGATCGGCGCGTTCTGCCGCTTCGCCGGTG
CGCGTGCCTATCTCGGCGCGTCGCAGCTCGGCGATTTCGACTGCCGGCCGCTCGCGGCCGCGTTGCAGGCCGACTGCCCG
ACGCTCGAGCACATCGTGATGGCCGGCGACGATCACGCGTTCACGTCGTTCGACGCGCTGTACGACGCGCCGCCCGTGCT
CCACTGCTCTGCACGCGCCGACGACATCGCGTGCTTCCAGCTGTCGGGCGGCACGACCGGCACGCCGAAGCTGATTCCGC
GCCGCCATCGCGAATACCTGTACAACGTGCGCGCGTGCAGCGCCGCGAGCGGTTTCGATGCCGACACCGTCTATCTCGCC
GCGCTGCCGATGGCGCACAACTTCACGCTGTGCTGCCCCGGCACGATCGGCGCATTGCTCGCAGGTGGCCGGGTGGTAAC
GACCGCGCGGCCCGAGCCCGACCAGAGCTTCGCGCTGATCACGCAGGAACGCGTCACGCATACCGCGCTCGTGCCGCCGC
TCGCGCTGCTGTGGCTCGACGAGCAGCCGCAACGGCAGACCGACCTGTCGAGCCTGCGCGTGCTGCAGGTCGGCGGCGCA
CGGCTGATGGACCACGCGGCCGAACGCGTGACGCCCGTGCTCGGCTGCCGGCTGCAGCAGGTGTTCGGCATGGCCGAAGG
GCTCATCTGCTGCACGCGGCTCGACGATGCGCCCGAGCGCATCGCGCACACGCAGGGCCGCCCCGTCTCCGAAGGCGACG
AAGTGCGCATCGTCGACGAAAGCGGCGCACCGGCCGCGGCCGGCGAGATCGGCGAATTGCAGGTACGCGGCCCGTACACG
ATCCGCGGCTACTACCGGCTCGCGGAGCACGACGCGACGGCGTTCACGGCCGACGGCTTCTACCGCAGCGGCGACCGCGT
GCGGCGCACCGCGGACGGCGACCTCGTCGTCGAAGGCCGCGACAAGGATCAGATCAACCGCGGCGGCGAGAAGGTCTCGG
CCGAGGAAGTGGAGAACCTGTTGCTCGCGCACCCGCAGGTGCACGATGCGGCGGTCGTCGCGATGCCCGACCCGATCCTC
GGCGAGCGAACCTGCGCGTTCGTGGTCGCACGCGCGCCGGCCCCGTCCCGACTCGTGCTGAAACGCTACCTGCGCGACCG
CGGGCTCGCGGCGTTCAAGATCCCCGACCGCATCGAATTCATGCCGCGCTTTCCGGAAACCGGCATCGGCAAGACCAGCA
AGAAATCGCTGCGCGACCTGCTGCGCCGCCAGTTGGAGGCGGCGGTCGCATGA

Protein sequence : 
MQSSPSSLAAAVPADAPDWPDDFARRYRDAGYWQDTTFFDALDACAERHPDALAVVDGTLRLRYRDLLARIRRLAGGLAR
LGLVRGDAVVVQLPNGARFIETCFALFQLGVRPVLALPAHRHYEIGAFCRFAGARAYLGASQLGDFDCRPLAAALQADCP
TLEHIVMAGDDHAFTSFDALYDAPPVLHCSARADDIACFQLSGGTTGTPKLIPRRHREYLYNVRACSAASGFDADTVYLA
ALPMAHNFTLCCPGTIGALLAGGRVVTTARPEPDQSFALITQERVTHTALVPPLALLWLDEQPQRQTDLSSLRVLQVGGA
RLMDHAAERVTPVLGCRLQQVFGMAEGLICCTRLDDAPERIAHTQGRPVSEGDEVRIVDESGAPAAAGEIGELQVRGPYT
IRGYYRLAEHDATAFTADGFYRSGDRVRRTADGDLVVEGRDKDQINRGGEKVSAEEVENLLLAHPQVHDAAVVAMPDPIL
GERTCAFVVARAPAPSRLVLKRYLRDRGLAAFKIPDRIEFMPRFPETGIGKTSKKSLRDLLRRQLEAAVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-99 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-99 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-99 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-99 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-99 50
ybtE CAA21394.1 - Virulence HPI Protein 3e-99 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 2e-98 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-99 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-98 50
irp2E YP_005163485.1 siderophore biosynthetic protein Virulence Not named Protein 3e-66 41
irp2E YP_005134497.1 siderophore biosynthetic protein Virulence Not named Protein 2e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcen2424_5000 YP_838627.1 AMP-dependent synthetase/ligase VFG0168 Protein 2e-163 68
Bcen2424_5000 YP_838627.1 AMP-dependent synthetase/ligase VFG0932 Protein 5e-97 45
Bcen2424_5000 YP_838627.1 AMP-dependent synthetase/ligase VFG1817 Protein 2e-87 45