Gene Information

Name : Bcen2424_0175 (Bcen2424_0175)
Accession : YP_833822.1
Strain :
Genome accession: NC_008542
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 193504 - 195177 bp
Length : 1674 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: bce:BC2304 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGACCGCCTCATCCCATGCCTCTCGCGACGTGTTCGACGGCGTGACGCCGTTTCCCGCCGACTACGCCGCCCGTTACCG
TGCGAAAGGTTATTGGCAGGACAAGCCGATGCGCCAGGTTTTCGGCGAATGGTGCCAGGCGCACGCGCCCAAAATCGCCT
TGCGCGACGCGACGCGCAGTGTGACTTTCGCGGAACTCGACGCGGCATCGACCAATCTCGCGCTTAACCTGCTTGATGTA
GGCATTCTTCCGGGCGACAAGCTCGTCGTGCAGTTGCCGAACGTCATCGAATTCGTGTATTTGCACTTTGCGTTGCAGAA
GATCGGCGCGATACCGGTGCTTGCGCTGCCGCCGCATCGCTACCGCGAGATCAGCTGCTTCGTCGAGATGGCGGAAGCGG
TCGCGCTCATCACGCCCGACGCACAAGGCGATTTCAGATACACGCAGATGACGGAACGCCTGCGCAACGAGGCACCGCGT
CTTCGCTTCGGCATCGTGTTAGGAGACGCACCCGAGGGCTTTGTCTCGCTACGCGACCTGATCGAGCGTCCTCCGGCACG
CGATGCGAGCGAACTGGACAACATCGCAATCGACCCATGCTCGCCGGCTCTCTTCTTGCTGTCCGGCGGCACCACCGGCA
TTCCCAAGCTGATCCCGCGCACCCATAACGACTACGTGCTCAACTCGAAGCTGGCCGCGGCCGTCTGCGATATACGCGAC
GGTGACGTCTTGCTCGATGTGCTCCCGATCGGTCACAACCTGCCGCTAGCGTGTCCCGGTCTGCAAGGTTTTCTGTCGCG
CGGCTGCACTGTCGTGCTGCATACGAGTACGTCGTCCGACCAGATCTTTCCGCTTATCGACCGCTACAAGGTCACGCATA
TCCATGTTGTGCCTGCACTGCTGATCCGCTGGCTGGAATCGCCGGTGATTGCGGACTTCGATCTCGGCTCGGTTCGGGTG
ATTCAGAGCGGCGGCCAGCGCTTGCAGCCTGAAACGCGCAAACGCACCCAGCAGCGGTTGCCGCAATGCTTCGTGCAGGA
GAACTTCGGCATGGCCGAGGGCGTGCTGATGTTCGTGCGTGCCGACGATCCGCTCGAAGTGCGCATGGAAACCGTCGGGC
GACCCGTTTGCGAAGACGACGAAGTCATGCTACTCGGTGAGGACGATCAGCCGGTACAGCCTGGCGAAGTGGGCGAACTG
TGCTGCCGCGGTCCGTACACTTTGCGCGGTTACTACCGTGCGCCCGAGCACAACGCACGCGCGTTCACGTCCGACGGCTT
TTATCGCAGCGGCGACCTCATGAGGCAACATCCGTCGGGCAACTACATTGTTGAAGGACGCAAGAAGGACCTGATCAATC
GCGGCGCGGAAAAGATCAGTGCAGAAGAGATCGAGAACCTGATTCTTGCGCACCCGGCCGTGGTGAACGTTGCCTGCGTG
GCGATGCCCGATCCGCTGATGGGAGAGCGCAATTGCGCGTGTCTGATTCTGCGTGAGGGCGTTTCATTGTCGCTCGACGA
ACTCGTTGCATTCCTGAAAAATCAGGAGATCGCCAAGTTCAAGCTTCCCGAACGCGTTGAGATCTTCACGTCATTTCCGC
TTTCGAATTTCGGTAAGGTCTCGAAGAAAGATCTGGCCGCAACGGTGGCCGAGCGCGTACAGGCGGCGCAATGA

Protein sequence : 
MTASSHASRDVFDGVTPFPADYAARYRAKGYWQDKPMRQVFGEWCQAHAPKIALRDATRSVTFAELDAASTNLALNLLDV
GILPGDKLVVQLPNVIEFVYLHFALQKIGAIPVLALPPHRYREISCFVEMAEAVALITPDAQGDFRYTQMTERLRNEAPR
LRFGIVLGDAPEGFVSLRDLIERPPARDASELDNIAIDPCSPALFLLSGGTTGIPKLIPRTHNDYVLNSKLAAAVCDIRD
GDVLLDVLPIGHNLPLACPGLQGFLSRGCTVVLHTSTSSDQIFPLIDRYKVTHIHVVPALLIRWLESPVIADFDLGSVRV
IQSGGQRLQPETRKRTQQRLPQCFVQENFGMAEGVLMFVRADDPLEVRMETVGRPVCEDDEVMLLGEDDQPVQPGEVGEL
CCRGPYTLRGYYRAPEHNARAFTSDGFYRSGDLMRQHPSGNYIVEGRKKDLINRGAEKISAEEIENLILAHPAVVNVACV
AMPDPLMGERNCACLILREGVSLSLDELVAFLKNQEIAKFKLPERVEIFTSFPLSNFGKVSKKDLAATVAERVQAAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-90 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-89 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 42
ybtE CAA21394.1 - Virulence HPI Protein 1e-89 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-89 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-89 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 9e-90 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcen2424_0175 YP_833822.1 AMP-dependent synthetase and ligase VFG0168 Protein 2e-93 43
Bcen2424_0175 YP_833822.1 AMP-dependent synthetase and ligase VFG0932 Protein 2e-88 42
Bcen2424_0175 YP_833822.1 AMP-dependent synthetase and ligase VFG1817 Protein 2e-95 42