Gene Information

Name : Arth_3061 (Arth_3061)
Accession : YP_832540.1
Strain : Arthrobacter sp. FB24
Genome accession: NC_008541
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 3432845 - 3434014 bp
Length : 1170 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGTCCAGAGAAAACCAAGGCTTCAACACCCGCGCCGTGCACGCCGGCCAGGCCTTTGAGCCGCGCACCGGCGCCGTGGT
GCCGCCCGTGCACTTCTCCACCACGTACGCCCAGGAAGCAATCGGGGTGCTCCGTGCCGGCTATGAATACGGCCGCGGCA
CGAACCCCACCCGGGACTCCCTGCAGGAACAGCTCGCAGCCCTCGAAGGCGGCTCACACGCGTACTCCTTCAGCTCAGGC
CTGGCCGCCGAGGACTCCCTCATCCGGGCCCTCACCCGCCCCGGGGACCACATCGTGCTGGGCAACGACGCCTACGGCGG
AACCTACCGCCTGATCAGCCGGGTCCTGGGCGAATGGGGGATCGGCAACACCCCAGTGGACATGGCGGACCTCGAGGCCG
TCGGCGCCGCGGTGGCAGCCCACAAGACCCGCCTCGTCTGGGTGGAGACCCCGTCCAACCCGATGATGAAGATCACTGAC
ATCGCGGCCCTCGCCAAGGTCGCGCACGACGCCGGCGCCCTCCTGGTGGTGGACAACACCTTCGCGTCGCCTTATTTGCA
GACTCCGCTGGCCCTTGGCGCCGACATCGTGGTGCACTCCACCACCAAGTACATCGGCGGCCACTCCGACGTCGTCGGCG
GGGCGATCGTGGTCAACGACGCGGACCTCGCCGAGAAGATCGGCTTCGTCCAGTTCGCCGTTGGCGCCGTCTCCGGGCCA
ATGGACGCCTTCCTAACCACCCGCGGGCTCAAGACCCTCGGCGTCCGGATGGACCGGCACAGCGACAACGCCCAGGCCGT
GGCCGAGTGGCTGCTGCAGCGCCCCGAAGTGGAGGCGGTGCTGTACCCGGGCCTGCCGTCGCACCCGGGCCACGAGCTGG
CCAAAAAGCAGATGAAGAAGTTCGGCGGCATGATTTCCGTGCAGTTCAGGGGCGGCGAGACCGCGGCCCGTACCGTTGCG
GAGAACACCTCGGTGTTCACCCTGGCCGAGTCCCTCGGCGGCATTGAATCGCTGATGAACTACCCGTCCGAAATGACGCA
CGCTTCGGTCAAGGGGACGGAACTGGCAGTGCCGGTCAATCTGATCCGGCTCTCCTGCGGCATCGAGGACGTCGAGGACC
TGATTGCGGACCTCGAGCACGCTTTCACCTTCATTGGTACGGGCAGCTAG

Protein sequence :
MSRENQGFNTRAVHAGQAFEPRTGAVVPPVHFSTTYAQEAIGVLRAGYEYGRGTNPTRDSLQEQLAALEGGSHAYSFSSG
LAAEDSLIRALTRPGDHIVLGNDAYGGTYRLISRVLGEWGIGNTPVDMADLEAVGAAVAAHKTRLVWVETPSNPMMKITD
IAALAKVAHDAGALLVVDNTFASPYLQTPLALGADIVVHSTTKYIGGHSDVVGGAIVVNDADLAEKIGFVQFAVGAVSGP
MDAFLTTRGLKTLGVRMDRHSDNAQAVAEWLLQRPEVEAVLYPGLPSHPGHELAKKQMKKFGGMISVQFRGGETAARTVA
ENTSVFTLAESLGGIESLMNYPSEMTHASVKGTELAVPVNLIRLSCGIEDVEDLIADLEHAFTFIGTGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-72 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-71 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-55 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Arth_3061 YP_832540.1 cystathionine gamma-synthase BAC0207 Protein 3e-66 44