Gene Information

Name : thyA (Arth_3018)
Accession : YP_832497.1
Strain : Arthrobacter sp. FB24
Genome accession: NC_008541
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3386774 - 3387577 bp
Length : 804 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGAGCATTCCAACGCCCTATGAAGACCTCCTGCGTGACGTCCTTGCCAACGGCACGCACAAATCTGACCGCACCGGCAC
CGGCACGCTCAGCGTGTTCGGGCGGCAGATGCGCTTTGACCTCAGCCAAAGCTTTCCGCTGATCACCACCAAGCGCGTTC
ATTTCAAGTCGGTGGCAGTTGAACTTCTATGGTTCCTGCGCGGCGAAACCAACGTGAAATGGATGCAGGACCAGGGCGTC
ACCATCTGGAACGAATGGGCCGACGCCGACGGCGAACTGGGTCCCGTTTACGGCGTGCAGTGGCGCAGCTGGCCGACGCC
CGACGGCGGCCACATCGACCAGATCGCCGAGCTGGTGGAGAACCTCAAATCCAACCCGGACTCGCGCCGGCACATCGTCT
CCGCCTGGAACGTGGCTGAGCTTCAGGACATGGCCTTGCCGCCGTGCCACGCGTTCTTCCAGTTCTACGTTGCTGACGGC
AAGCTGTCCTGCCAGCTGTACCAGCGCTCCGCGGACACCTTCCTTGGCGTCCCGTTTAACATCGCTTCCTATGCGCTGCT
GACCTGCATGCTGGCCCAACAGGTGGGCCTGGAGCCCGGCGAGTTCGTCTGGACCGGCGGCGACGTGCACATCTACGACA
ACCACATGGACCAGGTGCTCAAGCAGCTGAAGCGGGAGCCGTACGAATACCCGCAGCTGAAGATCCTCCGCAAGCCGGAC
TCCATTTTTGACTACACGCTGGACGACTTCGAAGTGGTCGGATACCAGCACCACCCTACGATTAAGGCGCCGATCGCAGT
ATGA

Protein sequence :
MSIPTPYEDLLRDVLANGTHKSDRTGTGTLSVFGRQMRFDLSQSFPLITTKRVHFKSVAVELLWFLRGETNVKWMQDQGV
TIWNEWADADGELGPVYGVQWRSWPTPDGGHIDQIAELVENLKSNPDSRRHIVSAWNVAELQDMALPPCHAFFQFYVADG
KLSCQLYQRSADTFLGVPFNIASYALLTCMLAQQVGLEPGEFVWTGGDVHIYDNHMDQVLKQLKREPYEYPQLKILRKPD
SIFDYTLDDFEVVGYQHHPTIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-92 71
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 7e-55 44