Gene Information

Name : guaA (Arth_2869)
Accession : YP_832348.1
Strain : Arthrobacter sp. FB24
Genome accession: NC_008541
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3227369 - 3228958 bp
Length : 1590 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTACTCCCACTGCATCCCAGACTTCCCAGAAGCCGGTGCTGGTTGTTGACTACGGTGCCCAGTACGCGCAGCTGAT
TGCCCGCCGCGTCCGGGAAGCAAATGTGTATTCGGAAGTGGTTCCGCATACCTACAGCACCGAACAACTGCTGGCCAAGA
ACCCCGCCGCCATCATCCTTTCGGGTGGCCCTTCCAGCGTGTACGCGGAAGGTGCACCGAGTGTGGGTGCCGACCTCTTT
GAAGCCGGGATCCCGGTCTTCGGCATCTGCTACGGCTTCCAGGCGATGGCCAACGCACTGGGCGGCACGGTCGCCCAGAC
AGGCCTGCGCGAATACGGCGCCACGGAAGCCACCACAGTAGGGGAGGCCCGGTCCATCCTGGACGGCCTGCCGCACCACC
AGAACACCTGGATGAGCCATGGCGATTCCGTGCAGGAAGCACCGGAAGGCTTTGAAGTCCTGGCCACCACCGCCGGTGCT
CCCGTGGCGGCATTCGCCAACGAGGAGAAGTGCCTTTACGGCGTGCAGTGGCACCCGGAGGTAAAACACTCCGCGTACGG
CCAGCAGGTGCTCGAGAACTTCCTGTTCAAGGGCGCCAAGCTCGAACCCAACTGGACCACGGGGAACATCCTCGAGGAAC
AGGTGGACCGCATCCGCAAGCAGATCGGAGACGCCAGGGTCATTTGCGGCCTTTCCGGCGGAGTCGACTCTGCGGTTGCG
GCTGCCCTGGTCCAGCGCGCCGTGGGCGATCAGCTGACCTGTGTGTTCGTGGACCACGGACTGCTCCGCGAAGGCGAGGC
GGAGCAGGTTGAACGCGACTTCGTGGCAGCCACGGGCGTCAAGCTGTACGTTGCCAACGAGCAGGAGAGGTTCCAGGCGG
CACTGGCCGGGGTCAGCGATCCCGAGACCAAGCGCAAGATCATCGGCCGCGAATTCATCCGTGCATTCGAGGAAGCGGAG
CTTGCCATCATCGCCGAGGCGGCTGCCCACGGTGAGAAGATCAAGTTCCTGGTCCAGGGGACCCTGTACCCGGACGTCGT
CGAATCCGGCGGCGGCGAAGGTGCGGCCAACATCAAGAGCCACCACAACGTGGGCGGCCTGCCGGAGGACCTGCAGTTCG
AACTCGTCGAGCCGCTTCGTGCGCTGTTCAAGGACGAAGTCCGTGCGGTGGGCGCCCAGCTGGGGCTGCCGCAGGAGATC
GTGGGCCGCCAGCCCTTCCCGGGGCCAGGCCTCGGCATCCGCATCGTCGGCGAAGTGACCAAGGAACGCCTGGACCTGCT
CCGCAAGGCCGACGCGATAGCCCGTGCCGAGCTCACTGCGGCCGGCCTTGACAACGAGGTGTGGCAGATGCCGGTCGTGC
TGCTGGCGGATGTCCGCAGCGTCGGTGTCCAGGGTGATGGCCGGACCTACGGCCATCCGATCGTCCTGCGTCCCGTTTCG
TCCGAGGACGCCATGACCGCCGACTGGTCACGGCTTCCGTACGAGTTGCTGGCAAAGATCTCCAACCGCATCACCAATGA
GGTGGAAGGCGTCAACCGGGTGGTGCTGGACGTGACCAGCAAGCCGCCGGGAACCATCGAGTGGGAATAG

Protein sequence :
MTTPTASQTSQKPVLVVDYGAQYAQLIARRVREANVYSEVVPHTYSTEQLLAKNPAAIILSGGPSSVYAEGAPSVGADLF
EAGIPVFGICYGFQAMANALGGTVAQTGLREYGATEATTVGEARSILDGLPHHQNTWMSHGDSVQEAPEGFEVLATTAGA
PVAAFANEEKCLYGVQWHPEVKHSAYGQQVLENFLFKGAKLEPNWTTGNILEEQVDRIRKQIGDARVICGLSGGVDSAVA
AALVQRAVGDQLTCVFVDHGLLREGEAEQVERDFVAATGVKLYVANEQERFQAALAGVSDPETKRKIIGREFIRAFEEAE
LAIIAEAAAHGEKIKFLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPEDLQFELVEPLRALFKDEVRAVGAQLGLPQEI
VGRQPFPGPGLGIRIVGEVTKERLDLLRKADAIARAELTAAGLDNEVWQMPVVLLADVRSVGVQGDGRTYGHPIVLRPVS
SEDAMTADWSRLPYELLAKISNRITNEVEGVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-165 72
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-126 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-126 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-125 50