Gene Information

Name : Arth_2487 (Arth_2487)
Accession : YP_831966.1
Strain : Arthrobacter sp. FB24
Genome accession: NC_008541
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2781177 - 2783057 bp
Length : 1881 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGAATACACAAGAAACACAGCTGATCCCTGCCCAAAACGAGGCCGCCCCCGGCAATTCGGCACCTGCCGAAGCGCAGTC
CCTGAAGTCGCACTCGCTGGCATTCATCACCGATGAAGCCACCGGGATCCGGGTGCCGGTGACCGAAATCGCCCTTGAGG
ACTCACCGGGCGGGGCAGCCAACCCGCCGTTCCGCGTGTACCGGACTGCCGGGCCCGGCAGCGATCCCGTGGTGGGCCTG
GAACCGTTCAGGACCCGGTGGATCGAGTCGCGGGCCGACACCGAGCCTTATGGCGGCCGGGAACGGAACCTGCTCGACGA
CGGCCGGTCGGCCGTGCGCCGCGGCGCCGCATCCGCGGAGTGGAAGGGCGCGCAGCCCGTGCCCCGCCGCGCCGTCGAAG
GCAGGACTGTCACGCAGATGCACTACGCCCGGCAGGGTGTCGTGACGCCGGAGATGCAGTTCGTTGCCCTCCGCGAAAAC
TGCGACGTGGAGCTGGTCCGCAGCGAAGTGGCTGCCGGCCGCGCCATCATCCCCAACAACATCAACCACCCGGAGTCCGA
ACCGATGATCATCGGCAAGGCCTTCCTGGTGAAGATCAACGCCAACATCGGCAACTCGGCCGTCACGAGCTCCATCGCGG
AGGAGGTCGACAAGCTGCAGTGGGCCACACTGTGGGGCGCCGACACCGTGATGGACCTGTCCACCGGCGATGACATCCAC
ACCACCCGTGAGTGGATCATCCGCAACTCCCCCGTGCCGATCGGCACCGTTCCCATCTACCAGGCACTGGAAAAGGTCAA
CGGCGAGGCCAACAAACTGACGTGGGAAATTTTCCGCGACACCGTGATCGAGCAGTGCGAGCAGGGCGTGGACTACATGA
CCATCCACGCCGGCGTGCTGCTGCGGTATGTGCCCCTGACCGCCAACCGGGTGACCGGCATCGTCTCCCGCGGCGGCTCC
ATCATGGCCGGCTGGTGCCTTGCCCACCACCAGGAGAACTTCCTGTACACGCACTTCGACGAGCTGTGCGAAATTTTCGC
CAAGTACGACGTCGCGTTTTCGCTGGGCGACGGGCTGCGGCCCGGTGCGACGGCGGACGCGAACGACGCCGCCCAGTTCG
CCGAGCTGGATACCCTGGCCGAACTGACGCAGCGCGCCTGGGAGTTCGACGTGCAGGTGATGGTGGAAGGACCCGGCCAC
GTGCCGTTCCACCTGGTCCGTGAAAACGTGGAACGCCAGCAGGAACTCTGCAAGGGAGCACCGTTCTACACGCTGGGGCC
GCTGGTCACGGACATAGCCCCGGGCTACGACCACATCACCTCCGCCATCGGCGCCACGGAAATCGCCCGCTACGGCACGG
CCATGCTCTGCTACGTCACGCCCAAGGAACACCTGGGGCTGCCAAACAAGGACGATGTCAAGACAGGCGTCATCACCTAC
AAGATCGCCGCCCACGCCGCCGACCTCGCCAAGGGCCACCCCGGCGCGCACCAACGCGACGACGCCCTGTCCAAGGCCCG
GTTCGAATTCCGCTGGCGGGACCAGTTCGCCCTCTCGCTGGACCCGGTCACCGCCGAATCCTTCCATGACGAGACGCTGC
CCGCGGAGCCAGCCAAGACCGCGCACTTCTGCTCCATGTGCGGGCCCAAGTTCTGCTCAATGCGCATCAGCCAGGACATC
AGGGACGAGTACGGTTCCGCCGAGGCACAGTCGGCACTCGCCGAGATGGCGGCAGGCATGCGTGAAAAGAGCAACGAATT
CCTCGCAGCCGGCGGCAAGGTCTACCTACCCGAGCTGCAGCTTCCAGACCCGGAACGACCGGGCCGGCACGGTGCAGCGA
CGGGCGACGCTACGACGCCCGTGAGTGCTGACGCCTGCTGA

Protein sequence :
MNTQETQLIPAQNEAAPGNSAPAEAQSLKSHSLAFITDEATGIRVPVTEIALEDSPGGAANPPFRVYRTAGPGSDPVVGL
EPFRTRWIESRADTEPYGGRERNLLDDGRSAVRRGAASAEWKGAQPVPRRAVEGRTVTQMHYARQGVVTPEMQFVALREN
CDVELVRSEVAAGRAIIPNNINHPESEPMIIGKAFLVKINANIGNSAVTSSIAEEVDKLQWATLWGADTVMDLSTGDDIH
TTREWIIRNSPVPIGTVPIYQALEKVNGEANKLTWEIFRDTVIEQCEQGVDYMTIHAGVLLRYVPLTANRVTGIVSRGGS
IMAGWCLAHHQENFLYTHFDELCEIFAKYDVAFSLGDGLRPGATADANDAAQFAELDTLAELTQRAWEFDVQVMVEGPGH
VPFHLVRENVERQQELCKGAPFYTLGPLVTDIAPGYDHITSAIGATEIARYGTAMLCYVTPKEHLGLPNKDDVKTGVITY
KIAAHAADLAKGHPGAHQRDDALSKARFEFRWRDQFALSLDPVTAESFHDETLPAEPAKTAHFCSMCGPKFCSMRISQDI
RDEYGSAEAQSALAEMAAGMREKSNEFLAAGGKVYLPELQLPDPERPGRHGAATGDATTPVSADAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-176 62
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-176 62
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-166 62