Gene Information

Name : leuS (Arth_2247)
Accession : YP_831727.1
Strain : Arthrobacter sp. FB24
Genome accession: NC_008541
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2527778 - 2530309 bp
Length : 2532 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGAGCGTTCAGCCGGAGACAGAGACCGGAACAGCAGCAGTCGCGACGGAAGGTCCCGAGGAGGGCACCTACAGCTTCGC
CGCGATGGAGGCCAAATGGCCGCAGGTGTGGGAAGACCTCAAGGTGTTCACACCCGTCGACGACGGCTCGCGCGAGCGCC
GCTACGTCCTCGACATGTTCCCCTACCCCTCAGGCGACCTGCACATGGGCCACGCCGAGGCGTTTGCCATGGGCGACGTC
GTGGCGCGCTACCTGCGCCAGAAGGGCTACGACGTCCTGCACCCGATCGGCTGGGACTCCTTCGGCTTGCCCGCCGAGAA
CGCCGCCATCAAGCGCAACGCGCACCCCAGCGAGTGGACCTACGCCAACATCGACACCCAGGCGGCGTCCTTCAAGCGCT
ATGCGATCTCGGCGGACTGGTCACGGCGCCTGCACACCTCGGACCCGGAGTACTACCGGTGGACCCAGTGGCTGTTCAAG
CGCTTCTACGAACGCGGCCTGGCGTACCGGAAGGATTCTCCGGTCAACTGGTGCCCCAAGGACCAGACCGTACTGGCCAA
CGAACAGGTGGTCAACGGGGCCTGTGAGCGCTGCGGCACCGCTGTAACCAAGAAGTCCCTGAACCAGTGGTACTTCAAGA
TCACCGACTACGCCGACCGGCTGCTGGACGACATGGACGAACTGCGCGGCCACTGGCCCGAGCGTGTCCTGGCCATGCAG
AAGAACTGGATCGGCCGGTCCGAAGGCGCCCACGTCAACTTCGTGATCGAGGCCGCCGGCGATAAGCCGGCCAAGGACGT
CACCGTCTTCACCACGCGCCCCGATACCCTCTACGGCGCCACGTTCTTCGTGGTTGCAGCAGATGCGCCGATGGCAGTGG
AGCTGGTCACGGACGAGCACGCCGCGGCCCTGGACGCGTACCGCGAACAGGTCAAGGCGCTGTCCGAAATCGAACGGCAG
TCCACCGAGCGCGAAAAGACGGGCGTCTTCACCGGCCGTTACGCCGTCAACCCACTGAACGGCGAAAAGCTGCCCGTCTG
GGCGGCCGACTACGTGCTGGCGGACTACGGCACGGGCGCCATCATGGCGGTCCCGGCCCACGACCAGCGCGACCTCGACT
TTGCCAGGACCTTCGACCTGCCCGTCCGCGCCGTGCTGGACACGGGGGAGGACGACCCCGCGGTGACCGGGAAGGCCACC
GCCGGGGAAGGCACCCTGATCAACTCCGGCGTGCTCGACGGCCTGCCCAAGGCCGAGGCCATCCCGACGGCGATCGACAT
GCTGGAGAAACAGGGCACGGGCGAAAAGTTCGTCAACTTCCGCCTGCGTGACTGGCTGCTCAGCCGCCAGCGCTTCTGGG
GCACGCCCATCCCGATCATCCACTGCCCTGCCTGCGGCGAAGTTCCGGTTCCCGACGACCAGCTGCCCGTCACCCTGCCG
GCCGACCTGCGCGGCGAGGACCTGTCCCCGAAGGGCACCTCGCCGCTGGCCGCGGCCGAGGCCTGGGTCAACGTTGAGTG
CCCCAACTGCCACGGTCCCGCCAAACGCGACACTGACACCATGGACACGTTCGTTGACTCGTCGTGGTACTTCCTGCGCT
TCGTGTCGCCGCAGTACACCGAGGGTCCCTTTGATCCCAAGAAGATCAACGACTGGATGCCTGTGGGGCAGTACGTGGGC
GGCGTGGAGCACGCCATCCTGCACCTGCTGTACGCCCGGTTCTTCACCAAGGTCATCCATGACCTCGGCATGATCGACGC
CGACGAACCGTTCAGCGCGCTGCTCAACCAGGGCCAGGTCCTCAACGGGGGCAAGGCCATGAGCAAGTCCCTGGGCAACG
GCGTCGACCTCGGTGAGCAGCTGGACAAGTACGGCGTCGACGCCGTGCGCCTCACCATGATCTTCGCCTCGCCGCCGGAG
GACGACGTCGACTGGGCTGACGTTTCGCCGTCGGGCTCCGCAAAGTTCCTGGCCCGGGCCTGGCGCCTGGCGCAGGACGT
AAGCAGCGCGCCCGGCGCGGACGCTGCCCAAGGAGACCGGGCGCTACGCTCCGTCACGCACCGCACCATCGCCGATGCCG
CCGCACTGCTGGACAGCAATAAGTTCAACGTGGTGGTGGCCAAACTGATGGAGCTGGTCAACGCGACCCGCAAAACCATA
GATGCAGCCTCCGGCGCGGGCGGGGCGGATCCCGCCGTCCGCGAAGCAGCGGAAGCTGTCGCGGTCATCCTAAGCCTTTT
CGCGCCGTACACGGCCGAGGACATGTGGAACGTTCTGGGGCATCCCGCCTCGGTGGCGAACGCCGGCTGGCCCTCGCATG
ACGAAGCGCTCCTGGTGCAGGACACGGTGACCGCCGTCGTCCAGGTCCAGGGCAAGGTCCGCGACCGTCTCGAAGTCTCT
CCGGAGATCGGCGAAGACGAGTTGCGTGAACTGGCCCTCGCGTCGGAGAACGTCCAGCGCGCCCTCGACGGGCGGGGTAT
CCGCACGGTCATCGTGCGTGCACCTAAACTGGTCAACATCGTCCCGGCGTAG

Protein sequence :
MSVQPETETGTAAVATEGPEEGTYSFAAMEAKWPQVWEDLKVFTPVDDGSRERRYVLDMFPYPSGDLHMGHAEAFAMGDV
VARYLRQKGYDVLHPIGWDSFGLPAENAAIKRNAHPSEWTYANIDTQAASFKRYAISADWSRRLHTSDPEYYRWTQWLFK
RFYERGLAYRKDSPVNWCPKDQTVLANEQVVNGACERCGTAVTKKSLNQWYFKITDYADRLLDDMDELRGHWPERVLAMQ
KNWIGRSEGAHVNFVIEAAGDKPAKDVTVFTTRPDTLYGATFFVVAADAPMAVELVTDEHAAALDAYREQVKALSEIERQ
STEREKTGVFTGRYAVNPLNGEKLPVWAADYVLADYGTGAIMAVPAHDQRDLDFARTFDLPVRAVLDTGEDDPAVTGKAT
AGEGTLINSGVLDGLPKAEAIPTAIDMLEKQGTGEKFVNFRLRDWLLSRQRFWGTPIPIIHCPACGEVPVPDDQLPVTLP
ADLRGEDLSPKGTSPLAAAEAWVNVECPNCHGPAKRDTDTMDTFVDSSWYFLRFVSPQYTEGPFDPKKINDWMPVGQYVG
GVEHAILHLLYARFFTKVIHDLGMIDADEPFSALLNQGQVLNGGKAMSKSLGNGVDLGEQLDKYGVDAVRLTMIFASPPE
DDVDWADVSPSGSAKFLARAWRLAQDVSSAPGADAAQGDRALRSVTHRTIADAAALLDSNKFNVVVAKLMELVNATRKTI
DAASGAGGADPAVREAAEAVAVILSLFAPYTAEDMWNVLGHPASVANAGWPSHDEALLVQDTVTAVVQVQGKVRDRLEVS
PEIGEDELRELALASENVQRALDGRGIRTVIVRAPKLVNIVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-159 42