Gene Information

Name : Arth_4465 (Arth_4465)
Accession : YP_829216.1
Strain :
Genome accession: NC_008537
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 86871 - 88301 bp
Length : 1431 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cjk:jk1442 putative mercuric reductase

DNA sequence : 
ATGGGAAACGAACGGTTCGATCTGGCGATCATCGGTTCCGGTGGCGCGGCGTTTGCGGCCGCGATCCGGGCCAGGGGGCT
GGGCAAGCGGGTAGTGATGATTGAGCGTGGCACCTTGGGCGGGACATGCGTGAACACCGGGTGCGTGCCGTCGAAGGCGC
TCCTGGCTGCCGCGGACGCCCGGCACGTGGCGTTGGACTCGGCCCGCTTCCCCGGCGTGATGGCCTCGGCCGGGGCCGTG
GACATTTCGGCCCTCATCGAGGGCAAGGCTGCACTTGTTGAAAGCATGCGGACAGAGAAGTACGTCGACCTTGCCGCGGA
CTATGGCTGGGCCATGCTCCAGGGAGACGCGGTATTCACCGGGACCCAGGACACACCTCTGCTCCAGGTCACCTCACCGG
GCGGTGCCGTTGAGACGATCGAGGCCGCACACTACCTTGTGGCCACCGGCTCCACACCATGGGCGCCGCCCGTTCCCGGA
CTGGCCGAGACCGGCTACCTGACCTCGACCACGGCGATGGAACTGGACGAAGTGCCCGAATCGTTGCTGGTCCTTGGCGG
CGGCTATGTCGCCCTAGAGCAGGCGCAGCTGTTCTCCCGGCTCGGCTCCCGCGTGACTATGCTCGTCCGCTCCAGGCTCA
CCTCGCACGAGGAGCCGGAAGTATCCAAGGCGCTGGCCGGGGTCTTCGCGGATGAGGGGATCCGGGTGGTCCGGCGGGCC
ACCGTGGACTCAGTGAGCCTCGATGAGGCCACCGGCGGGGTCAGCGCCACCGCTTCGGTGGCCGGTGGACAGGAAGTGTT
CCGGGCCTCCCGGCTGCTCGTGGCCCTGGGGCGCCGGCCCGTCACCGAGGGGCTGAACCTCGACGCCGTCGGGGTGAAGA
CCGGCACGTCCGGTGAGATCGTGGTCGATTCCCGTCTGGCCAGCTCGAACCCCAGGATCTGGGCTGCAGGGGATGTCACC
GGCCACCGTGAGTTCGTCTACGTCGCCGCGGCCCACGGCGCCCTTGCCGTGGAGAACGCGTTTACCGACGCCGTGGATGA
GGTCGACTACCGGCATCTGCCGCGGGTGACCTTCACCAGCCCGGCTGTGGGTGCCGTCGGGATGACTGAGCAGGACGCGG
TCGCTGCCGGTATCCGCTGCGACTGCCGGGTGCTGCCCCTGAACTACGTCCCCAGGGCCCTGGTCAACCGCGATACCCGG
GGATTCATCAAAGTCGTTGCCGACCGTGACACCGGCCGGATCGTGGGCCTCACCGCCGTGGCCAAGGACGCGGGCGAGCT
GGCCGCCGCGGGCGTCTACCTGCTCGAGGCGGGGATGACCACCGGGCAGGTCGCCGGCATGTGGAGCCCCTACCTGACCA
TGGCCGAGGGCATCAGGATCGCCTGCAAGGCCTTCACCACAGACGTCTCCAAACTCTCCTGCTGCGCCTAA

Protein sequence : 
MGNERFDLAIIGSGGAAFAAAIRARGLGKRVVMIERGTLGGTCVNTGCVPSKALLAAADARHVALDSARFPGVMASAGAV
DISALIEGKAALVESMRTEKYVDLAADYGWAMLQGDAVFTGTQDTPLLQVTSPGGAVETIEAAHYLVATGSTPWAPPVPG
LAETGYLTSTTAMELDEVPESLLVLGGGYVALEQAQLFSRLGSRVTMLVRSRLTSHEEPEVSKALAGVFADEGIRVVRRA
TVDSVSLDEATGGVSATASVAGGQEVFRASRLLVALGRRPVTEGLNLDAVGVKTGTSGEIVVDSRLASSNPRIWAAGDVT
GHREFVYVAAAHGALAVENAFTDAVDEVDYRHLPRVTFTSPAVGAVGMTEQDAVAAGIRCDCRVLPLNYVPRALVNRDTR
GFIKVVADRDTGRIVGLTAVAKDAGELAAAGVYLLEAGMTTGQVAGMWSPYLTMAEGIRIACKAFTTDVSKLSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-82 44
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-82 44
merA AGK07079.1 MerA Not tested SGI1 Protein 4e-67 43
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-67 43
merA ABQ57371.1 MerA Not tested SGI1 Protein 4e-67 43
merA AGK07021.1 MerA Not tested SGI1 Protein 4e-67 43
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 7e-67 43
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 2e-67 43
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 6e-63 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 1e-65 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 1e-65 41
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 1e-65 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Arth_4465 YP_829216.1 mercuric reductase BAC0224 Protein 3e-81 45
Arth_4465 YP_829216.1 mercuric reductase BAC0651 Protein 2e-82 44
Arth_4465 YP_829216.1 mercuric reductase BAC0652 Protein 1e-67 43