Gene Information

Name : Acid_6216 (Acid_6216)
Accession : YP_827427.1
Strain : Candidatus Solibacter usitatus Ellin6076
Genome accession: NC_008536
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 7794309 - 7795067 bp
Length : 759 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
GTGCCGCGTAAAATTCTCGGCGTCATCCCTGCTAGATTCTCCTCTACTCGATTTCCCGGCAAGGTTTTGGCTCAAATCGC
CAACAAAACCATGCTGCAGCACGTTTACGAGCGTGCCGGGCTCGCAACTTACCTCACGAGCACGATCATTGCCACGGATG
ACGAGCGCGTCTACACAGCTGCAAAAAGTTTCGGCGCACGGGTACGAATGACACGCGCCGACCACCTTTCAGGCACGGAC
CGCGTGGCCGAGGTGGCTTCCGCGGAGAACGCCGAAATCATCGTCAACATTCAAGGCGACGAGCCGTTGATCGATCCGGC
GGCGATCGATGCCGCTGTATTGCCGTTGGTGCATGAGCCCGACGTGCTCATGGGGACGCTCAAGAAGCGGATCGAAGATC
CGCGCGAAATCGTCGATCCCAACGTGGTTAAGGTTGTCACAGACCATGCGGGGGATGCGATCTATTTTTCCCGGTGCCCG
ATTCCGTTCGATCGCGACCGTTCCGCCGACACGCCCTATTTCAAGCATGTCGGGCTATACGTCTACCAGCGGGATTTCCT
GCTCTCCTATTCCACGCTGCCGGTAGGGCCGCTGGAACGGTCGGAGCGGCTGGAGCAGTTGCGTGCGTTGGAAAACGGAT
ATCGAATCCGGGTGGTGGAAACCGAATACGAGTCGTTGGGCGTGGATACGCCGGAGGATCTGGAAAGGGTGAGCAGATTG
TTCAAAGCCTCAATCTTACAAGGGATGGGAAATGGCTAA

Protein sequence : 
MPRKILGVIPARFSSTRFPGKVLAQIANKTMLQHVYERAGLATYLTSTIIATDDERVYTAAKSFGARVRMTRADHLSGTD
RVAEVASAENAEIIVNIQGDEPLIDPAAIDAAVLPLVHEPDVLMGTLKKRIEDPREIVDPNVVKVVTDHAGDAIYFSRCP
IPFDRDRSADTPYFKHVGLYVYQRDFLLSYSTLPVGPLERSERLEQLRALENGYRIRVVETEYESLGVDTPEDLERVSRL
FKASILQGMGNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-43 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-44 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-44 45