Gene Information

Name : leuS (Acid_5844)
Accession : YP_827074.1
Strain : Candidatus Solibacter usitatus Ellin6076
Genome accession: NC_008536
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 7319529 - 7321961 bp
Length : 2433 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCCCGAGAAGCCATACGACCACATCGCTATCGAATTGAAGTGGCACGAGCGTTGGCAGGACGCCCAGTTCTACAAAGC
CGAGGAGAATTCCGCCAAGCCGAAGTTCTATGTGCTGGAGATGCTCCCGTACCCGAGCGGCACCCTCCATATCGGCCACA
TCCGCAACTATTCGATTGGCGACGCGCTGGCTCGCTATAAGTGGATGCGCGGCTTCAACGTGCTTCACCCCATGGGGTGG
GACGCCTTCGGACTCCCCGCCGAAAACGCCGCCATCGCCAACAAAGTTCCGCCGCGCCAGTGGACCTTGCAGAACATCGC
GGCCATGAAGAAGACCCACCGCCGCTTCGCCTTCAGCTACGATTGGGACCGCGAAGTCTCCACCTGCGAGCCCGAGTATT
ATCGCTGGAATCAGTGGTTCTTCCTCCGCATGCTGGAGCGCGGCCTCGCCTATCGCAAGCGCGCCCTCGTCAACTGGTGC
CCCAAATGCGCCACCGTGCTCGCCAATGAGCAGGTGGTGGATGGCTGCTGCTGGCGGCACGAAGGCACGCCCGTGGAACA
GCGCGCGCTCGACCAATGGTTCCTCAAGATCACCGACTACGCCGATCAGCTTCTGGATGAAATGGCCAGGCTCGAAGGCG
GCTGGCCCGAGCGCGTGCTCACCATGCAGCGCAACTGGATCGGCCGCTCCGAGGGCGCCGAGATCGATTTCACTCTCGCC
GGCGCCGGCACGCCCATTCGCGTCTTCACCACCCGCGTGGACACAATCTACGGCGCAACCTCCGTGATCCTCGCGCCCGA
ACATCCGCTCAACGAAACACTCCTCGATAGCGAGAAGAAAGCCAAAGCAAAGGCCATGGTCGATTCGCGCGCGGGCCGCG
ACCCTGGCGATATCGATAAGGAGGGCTTCTTCACCGGCCACTACGCCGTCAATCCATACAACGGAGAACAGGTCCCCATC
TGGATTGCCAACTTTGTCCTTATGGGGTACGGCACCGGCGCCATCATGGCCGTCCCCGCGCATGATGAGCGCGATTTCGA
ATTTTGCACAAAGTACGGGATTCCGATTACCCCGGTAATCCGCCCCGTCGATCAACCGGCCGGCGAACCGGTCGCCTTAC
CCTACGGCGAATACGGCATCCTCGAAAATTCCGGCGAATGGAGCGGGCTCGCGAGCGCGGAGGCTCGCCGCCAAATGAGC
GCGTACGCCGAGCAGCACGGCTTCGGCAAGTCCGCCATTACGTTCCGCATCAAAGACTGGGGCATCTCCCGACAGCGCTA
TTGGGGCACTCCGATTCCCGTCATCCACTGCCCGTCCTGCGGCGTGGTACCGGTGCCCGACGACCAGCTCCCGGTGGTCC
TCCCCGACCGTATTGAGATCACCGGCGCAGGACGCTCGCCGCTCGAAAACGTCCCCGAGTTCGTCAATGTCGCCTGTCCG
AAATGCGGCGAGCCCGCGCGGCGTGAGACCGATACCATGGACACCTTCGTGGATAGCTCCTGGTATTTCTACCGCTACTG
CGATCCGCACAACTCCGAGCGTCCGTTCGACCCCGCGAAGATCGCCTACTGGTTCGAGATCGATCAATACATCGGCGGCA
TCGAGCACGCCATTCTTCACCTCATCTATTCGCGCTTCTTCACGAAGGTAATGCGCGATATCGGACTCATCTCAAACAAC
GAGCCCGCGCGCCGCCTCTTCACCCAGGGAATGGTGATCGCTGAGGGCGCCAAGATGTCCAAGTCCAAAGGCAATGTGGT
TGGCGCGGATTTGCTCGCCGATAAATTCGGCGCCGATACCGCCCGCATGTTCGTGCTCTCCAACGTGCCGCCCGAGAAGG
AGGTGGATTGGCGCGAGGAAGGCGCCGAGGGCACCTACCGTTTTCTCGGCCGCGTCTACCGCTTCACCACGCGCAACGTC
CCCGCGCAACAGCGCTCCGGCGACGCCGATCGCAAAGTGGTCCGCAAGCTTCACCAGACCCTGAAGAAGATCACCGAGGA
TTTCGAGACCCGGTGGCACTTCAACACCTGCATCGCCTCCATCATGGAGTTGGTCAACCTGCTCTACGCGGAGGAGCAGA
ACATCTCCGCCGCCGTGATGCCGCAGATTCTCGAGAGCCTCGCGCTCATGCTCGCGCCTTTCGCGCCTTACCTATCCCAG
GAAATGTGGGAAGAGATCGGCAAAGAAGGCCCGGTTTTCCGCCAGGCGTGGCCGGCCTTCGACCCCGAGCTGGCCAAGGA
AGAGGGAGCCGAGATCGTGGTGCAGGTCAACGGCAAGGTCCGCACCCGCATCACCGCGCCCTTCGGCACCGCGAAGGAAG
AGCTCGAATCACGCTCTCTCGCCCACGAAAAAGTGAAGCCCTTCATCGACGGCAAGCAGGTGATGAAGATTATCACCGTC
CCCGACAAACTCGTCAACATCGTGGTGAAGTGA

Protein sequence :
MPEKPYDHIAIELKWHERWQDAQFYKAEENSAKPKFYVLEMLPYPSGTLHIGHIRNYSIGDALARYKWMRGFNVLHPMGW
DAFGLPAENAAIANKVPPRQWTLQNIAAMKKTHRRFAFSYDWDREVSTCEPEYYRWNQWFFLRMLERGLAYRKRALVNWC
PKCATVLANEQVVDGCCWRHEGTPVEQRALDQWFLKITDYADQLLDEMARLEGGWPERVLTMQRNWIGRSEGAEIDFTLA
GAGTPIRVFTTRVDTIYGATSVILAPEHPLNETLLDSEKKAKAKAMVDSRAGRDPGDIDKEGFFTGHYAVNPYNGEQVPI
WIANFVLMGYGTGAIMAVPAHDERDFEFCTKYGIPITPVIRPVDQPAGEPVALPYGEYGILENSGEWSGLASAEARRQMS
AYAEQHGFGKSAITFRIKDWGISRQRYWGTPIPVIHCPSCGVVPVPDDQLPVVLPDRIEITGAGRSPLENVPEFVNVACP
KCGEPARRETDTMDTFVDSSWYFYRYCDPHNSERPFDPAKIAYWFEIDQYIGGIEHAILHLIYSRFFTKVMRDIGLISNN
EPARRLFTQGMVIAEGAKMSKSKGNVVGADLLADKFGADTARMFVLSNVPPEKEVDWREEGAEGTYRFLGRVYRFTTRNV
PAQQRSGDADRKVVRKLHQTLKKITEDFETRWHFNTCIASIMELVNLLYAEEQNISAAVMPQILESLALMLAPFAPYLSQ
EMWEEIGKEGPVFRQAWPAFDPELAKEEGAEIVVQVNGKVRTRITAPFGTAKEELESRSLAHEKVKPFIDGKQVMKIITV
PDKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-154 41