Gene Information

Name : SPD_0143 (SPD_0143)
Accession : YP_815662.1
Strain : Streptococcus pneumoniae D39
Genome accession: NC_008533
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 147932 - 149104 bp
Length : 1173 bp
Strand : +
Note : equivalent gene in S.pneumoniae R6 = spr0139; identified by match to protein family HMM PF00984; match to protein family HMM PF03721

DNA sequence : 
ATGAATATAGCAGTAATTGGTTTGGGGCATGTTGGGCTGGCCTACGCGTTACTATTTGCATCTAAATATAAAGTTGTTGC
ATATGATATAGATTCTGTAAAAATAAATAATTTAAAAAAGGGCATTCTTCCATCTAAAAATGAAGAGCTTATGAAGTTTT
TTTGCGAGAATAACTTAAATATTACTTTTTTTGATACATTTTCTGAAATTAAAAATAATATTGATTATTATATTATTGCG
CTTCCGACAGATTATGATGAGAAAATTGGTAGTTTTAATACATATGAAATCGAACAAACGGTATCGAAGATTCTGAGGGT
AAAACCTAATGGAAAGATTATTTTAAAGTCAACAGTTCCGATCGGCTTTTCAAACAAATTAAAAAGGCTGTTTGATACAA
AAAATATCATTTTTGTCCCTGAATTTTTGAGAGAAGGTTGTTCTATATATGATAATTTATATCCAAGTCGCATAGTTGTT
GGAGATGAGACAGTTGAAGGAAGAAAAATTGCAGAGTTGTTCCTTTCGATTAGTACTCATAGTACTGCCAATATTAAAAA
TGTTATGTTAGTTTCTCCTACTGAAGCAGAAGCAATTAAGCTTTTTTCTAACACATTCTTAGCTCTCCGTGTTGCTTTTT
TTAATGAACTAGATTCTTTTGCTGAGAGGAGAAGTTTAAATGCTGAAGTTGTAATAAAAGGTGTTTGTTTAGATCCAAGA
ATTGGAAATTTTTATAATAATCCTTCTTTTGGATTTGGAGGATATTGTCTTCCCAAAGATACTAAACAATTAAAAAAAGA
ATTTATAGAAATAAATGCCCCAGTGATAGAAGCGATTGATATTTCAAACACAAATAGAAAACAGTTCATAGTTAAACAAA
TATTGGAACGAAAGCCAAAGATAGTAGGAATATATAAATTGGGGATGAAATATAATTCAGATAATTACAAAGAGTCAGCT
ATTTTAAGTATAATTAATGAACTATTGATTGTCGGTATAAAAATTTTAGTATATGAACCAAATTTAAACGTTAGTATAGA
TAACGTAATTTTTGAAAAGAATTTTGAACTATTTACAAAACAAAGTGATCTAATTGTTGCAAATAGATGGGATAGGGGCC
TTGAAGCTTATAAAGATAAAGTTTACACAAGGGGGATCTGGATAAGAGATTAA

Protein sequence : 
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIA
LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESA
ILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 4e-72 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPD_0143 YP_815662.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 7e-71 45