Gene Information

Name : secA (STER_1705)
Accession : YP_821044.1
Strain : Streptococcus thermophilus LMD-9
Genome accession: NC_008532
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1594955 - 1597504 bp
Length : 2550 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAATATATTACGCAAAATCATTGAAAATGATAAGGGCGAAATTAAAAAACTAGAAAAAACTGCCAAGAAAGTTGA
GAGCTATGCTGATGCAATGGCGGCTCTTTCAGATGAAGAACTTCAGGCAAAAACAGAAGAATTTAAACAACGATATCAAA
ACGGAGAAAGTCTAGATCAGCTCTTGCCGGAGGCATTTGCGGTTGTTCGTGAGGGAGCGAAACGTGTCCTTGGACTTTTC
CCATATCGTGTGCAAATTATGGGTGGTATTGTGCTTCACTATGGTGACGTAGCGGAGATGCGTACAGGGGAAGGGAAAAC
CCTTACTGCGACAATGCCTGTCTACTTGAATGCTATTTCAGGTGAAGGTGTACACGTTATCACCGTTAACGAATACCTTT
CAGAGCGTGATGCGACTGAAATGGGTGAGCTTTATAGTTGGCTCGGTTTGTCAGTAGGGATCAACCTTTCATCTAAATCA
CCAGCTGAAAAACGTGAAGCTTATAATTGTGACATCACTTACTCAACCAGCTCAGAGGTAGGTTTCGACTATCTTCGTGA
TAATATGGTTGTTCGTAAGGAAAACATGGTACAACGCCCATTGAACTTTGCCTTGGTCGATGAGGTTGACTCGGTTCTTA
TTGATGAAGCTCGTACACCATTGATCGTATCAGGGCCTGTAAGTTCAGAAACTAATCAGTTGTATCACCGTGCGGATGCT
TTTGTTAAGACATTGACTGAAGATGATTATGCGATTGATATTCCAACAAAAACAATTGGTTTGAATGACTCAGGTATTGA
CAAGGCTGAAGAGTTCTTCAACTTGGAAAATTTGTACGATATTGACAATGTTGCCTTGACTCACTATATTGACAATGCCC
TTCGTGCCAACTACATTATGTTGCGTGATATTGACTACGTGGTAAGTCCTGAGCAAGAAATCCTTATTGTTGACCAATTT
ACTGGTCGTACCATGGAAGGTCGTCGTTTTTCAGATGGGCTCCACCAAGCCATTGAGGCTAAAGAAGGTGTACCAGTCCA
AGAGGAAACCAAGACTTCTGCCTCAATCACTTACCAAAATATGTTCCGTATGTACAAGAAATTGTCAGGTATGACTGGTA
CTGGTAAGACTGAAGAGGATGAATTCCGTGAAATCTATAACATGCGAGTCATCCCAATTCCAACAAACCGTCCAATTCAA
CGTATTGACCATGATGACCTTCTGTACTCAACTTTGGATGCTAAATTCCGTGCTGTGGTACAAGATGTTAAGCGTCGTTA
TGAGAAGGGGCAACCAGTTCTTATTGGTACGGTTGCCGTTGAAACATCTGACTTGATTTCTAAGATGTTGGTTGACGCAG
GTATTCCTCACGAGGTGCTTAATGCCAAGAACCACGAAAAAGAAGCGCATATTATCATGAATGCAGGTCAACGTGGTGCT
GTTACGATTGCGACCAATATGGCCGGTCGTGGTACTGACATCAAACTTGGTGAAGGTGTTCTGGAGCTTGGTGGACTTTG
TGTCATTGGTACAGAGCGTCATGAAAGTCGTCGTATCGACAACCAGTTGCGTGGTCGTTCGGGACGTCAAGGGGATCCAG
GGGAGTCTCAATTCTACCTATCTCTTGAAGACGAATTGATGCGTCGTTTCGGTTCTGACCGTATCAAGCATGTCTTGGAA
CGTTTGAACGCTGATGACGAAGATATTGTTATCAAATCACGTATGTTGACCCGTCAAGTGGAATCAGCTCAAAAACGTGT
CGAAGGGAATAACTACGATACTCGTAAACAAGTTCTTCAGTACGATGACGTTATGCGTGAACAGCGTGAAATCATCTACG
CTGAGCGTTATGATGTTATTACAGCAGAACGTGACCTTGAACCTGAAATCAAGGCTATGATCAAGCGTACTATTAACCGT
ACGGTTGATGGACACAGTCGTAACGATCAAGAAGAAGCTCTTAAAGGTATCTTGAACTTTGCACGTCAGGCCTTGGTTCC
TGAGGATGCCATCTCGCTTGAAGATCTAAAAGAAGTGGGAGAGGTGACTAAACGTAGTGTTAATTATGATGCTATCAAGG
TTTATCTGACTGAGTTAGCAGATAATGTTTATGATCGTCAAATTAAGAAATTGCGTTCAGAGGAGGCTATTCGCGAATTC
CAAAAAGTCTTGATTTTGATGGTTGTTGATAATAAGTGGACAGACCACATTGATGCCCTTGATCAATTACGTAACGCCGT
TGGTATGCGTGGTTATGCGCAAAACAACCCAATCGTTGAGTATCAATCTGAAAGTTTCAAGATGTTCCAAGATATGATTG
GTGCTATTGAGTATGATGTAACTCGTACGATGATGAAAGCACAAATCCACGAACAATCTCGTGAACATGTTAATGAACGT
GTTTCAACAACAGCAACAGGCAATATTCAAGCACATCAAGCAGATGCTAACGGTCAAGAGATTGACTTTAGCAAGGTTGG
TCGTAATGACTTCTGTCCATGTGGCTCTGGTAAGAAATTCAAAAATTGTCACGGTCGTAAACAGTTTTAG

Protein sequence :
MANILRKIIENDKGEIKKLEKTAKKVESYADAMAALSDEELQAKTEEFKQRYQNGESLDQLLPEAFAVVREGAKRVLGLF
PYRVQIMGGIVLHYGDVAEMRTGEGKTLTATMPVYLNAISGEGVHVITVNEYLSERDATEMGELYSWLGLSVGINLSSKS
PAEKREAYNCDITYSTSSEVGFDYLRDNMVVRKENMVQRPLNFALVDEVDSVLIDEARTPLIVSGPVSSETNQLYHRADA
FVKTLTEDDYAIDIPTKTIGLNDSGIDKAEEFFNLENLYDIDNVALTHYIDNALRANYIMLRDIDYVVSPEQEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVPVQEETKTSASITYQNMFRMYKKLSGMTGTGKTEEDEFREIYNMRVIPIPTNRPIQ
RIDHDDLLYSTLDAKFRAVVQDVKRRYEKGQPVLIGTVAVETSDLISKMLVDAGIPHEVLNAKNHEKEAHIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVLELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSDRIKHVLE
RLNADDEDIVIKSRMLTRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERYDVITAERDLEPEIKAMIKRTINR
TVDGHSRNDQEEALKGILNFARQALVPEDAISLEDLKEVGEVTKRSVNYDAIKVYLTELADNVYDRQIKKLRSEEAIREF
QKVLILMVVDNKWTDHIDALDQLRNAVGMRGYAQNNPIVEYQSESFKMFQDMIGAIEYDVTRTMMKAQIHEQSREHVNER
VSTTATGNIQAHQADANGQEIDFSKVGRNDFCPCGSGKKFKNCHGRKQF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 8e-140 41