Gene Information

Name : nrdF (STER_1249)
Accession : YP_820633.1
Strain : Streptococcus thermophilus LMD-9
Genome accession: NC_008532
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1156775 - 1157737 bp
Length : 963 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGAAACTTACTATAAAGCCATTAACTGGAATGAAATCGAAGATGCGATTGATAAATCTACCTGGGAAAAATTAACTGA
ACAATTTTGGTTAGATACTCGAATTCCCCTTTCAAATGACCTTGATGACTGGCGTAAACTTTCAGCTGAAGAAAAAGATT
TAGTTGGAAAAGTTTTCGGCGGCTTGACCTTGCTAGATACCATGCAATCTCAAACGGGTGTTGAAGCCATTCGAGCAGAC
GTTCGTACACCTCATGAAGAAGCTGTCTTGAACAACATTCAGTTTATGGAATCTGTTCATGCAAAATCTTACTCTTCTAT
TTTCTCAACTTTGAATACTAAATCAGAAATTGAGGAAATTTTTGAGTGGACAAACAGCAACAAGTACTTGCAAACTAAAG
CAAAAATCATTAATGATATCTATGAAAACGGAACGGCACTTCAGAAAAAAGTTGCTTCAACTTATCTTGAAACCTTCCTT
TTCTATTCAGGCTTCTTCACTCCACTCTATTATCTTGGTAATAATAAGCTAGCTAATGTCGCTGAAATTATCAAACTCAT
TATCCGTGACGAATCTGTTCACGGTACCTATATTGGCTATAAGTTCCAACTAGGATTCAACGAATTACCTGAAAAAGAGC
AGGAGAGTTTCCGTGAATGGATGTATGATCTCCTCTATCAATTATATGAAAATGAAGAACTCTACACTAAATCTCTTTAT
GACGGTGTTGGATGGACCGAAGAAGTAATGACCTTTCTTCGCTATAACGCCAATAAAGCATTGATGAATTTAGGACAAGA
TCCTCTTTTCCCAGATTCTGCTAACGATGTTAACCCAATCGTTATGAATGGTATTTCTACAGGAACATCAAACCACGATT
TCTTTTCTCAAGTCGGTAATGGTTACCTTCTAGGTACTGTTGAAGCTATGCAAGATGATGATTATAACTACGGACTAAAA
TAA

Protein sequence :
METYYKAINWNEIEDAIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSAEEKDLVGKVFGGLTLLDTMQSQTGVEAIRAD
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKSEIEEIFEWTNSNKYLQTKAKIINDIYENGTALQKKVASTYLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEKEQESFREWMYDLLYQLYENEELYTKSLY
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDSANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMQDDDYNYGLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 1e-67 48