Gene Information

Name : STER_1163 (STER_1163)
Accession : YP_820550.1
Strain : Streptococcus thermophilus LMD-9
Genome accession: NC_008532
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1071653 - 1073155 bp
Length : 1503 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAATAAACGCGTAAAAATAGTTGCTACACTTGGTCCTGCGGTTGAAATCCGTGGTGGCAAGAAATTTGGTGAAGATGG
TTACTGGAGTGAAAAACTTGACCCTGATGCATCTGCTAAAAACATTGCTCAATTGATCGAGGAAGGTGCTAACGTTTTCC
GTTTCAACTTCTCACATGGTAACCACGCTGAGCAAGGTGAACGTATGGATGTCGTACGTATGGCTGAATCTATTGCTGGT
CAAAAAGTAGGTTTCCTTCTTGACACTAAGGGACCTGAAATCCGTACTGAATTGTTTGAAGGTGATGCTAAAGAGTATGC
ATACAAAACTGGTGAACAAATCCGTATTGCTACTAAACAAGGTCTCAAATCAACTCGCGACGTTATTGCTTTGAACGTTG
CTGGTGCACTTGACATTTTCGACGATGTAGAAGTTGGTAAACAAGTTCTTGTGGATGATGGTAAACTTGGTCTTCGTGTT
GTAGACAAGGATGCTGAAAAACGTGAATTCATCGTTGAAGTTGAAAATGATGGTATTATTGCTAAACAAAAAGGTGTAAA
CATCCCTTACACTAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAATGCTGATATTCGTTTTGGTCTCGAACAAGGTA
TTAACTTTATCGCAATCTCATTTGTACGTACTGCGAAAGACGTACAAGAAGTACGTGCTATCTGTGAAGAAACTGGAAAC
GGCCACGTTAAATTGTTGGCTAAAATCGAAAACCAACAAGGTATCGATAATATCGATGAAATCATTGAAGCTGCTGATGG
TATCATGATCGCTCGTGGTGACATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATTATCACTA
AAGTAAATGCTGCTGGTAAATTTGTTGTTACAGCTACAAACATGCTTGAAACAATGACAGAAAAACCACGTGCAACTCGT
GCTGAAGTATCTGACGTGTTTAATGCTGTTATCGATGGTACTGATGCGACAATGCTTTCTGGTGAGTCTGCAAACGGTAA
ATATCCAGTTGAATCAGTTCATACAATGGCTACAATTAATAAAAACGCTCAAGCTCTTCTTAAAGAGTATGGTCGTCTTG
ATCCATCAACATTTGATCGCTCAAGTAAAACTGAAGTTGTTGCATCTGCAGTTAAAGAAGCTACCAACTCAATGGATATC
AAACTTATTGTTGCACTTACTGAATCTGGTAACACAGCTCGTTTGATTTCTAAATACCGTCCAGAAGCTGACATCTTGGC
AGTAACATTCGATGAACTTACTCAAAAATCATTGATGCTTAACTGGGGTGTTATTCCAATTGTTACTGAAACACCTTCAT
CTACTGATGATATGTTTGAAGTTGCTGAGCGTGTTGCTCTTGAATCAGGTCTTGTAGAATCAGGTGATAACATTGTTATT
GTTGCTGGTATTCCAGTTGGTTCTGGTAATACAAATACTATGCGTATCCGCACAGTTAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWSEKLDPDASAKNIAQLIEEGANVFRFNFSHGNHAEQGERMDVVRMAESIAG
QKVGFLLDTKGPEIRTELFEGDAKEYAYKTGEQIRIATKQGLKSTRDVIALNVAGALDIFDDVEVGKQVLVDDGKLGLRV
VDKDAEKREFIVEVENDGIIAKQKGVNIPYTKIPFPALAERDNADIRFGLEQGINFIAISFVRTAKDVQEVRAICEETGN
GHVKLLAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKFVVTATNMLETMTEKPRATR
AEVSDVFNAVIDGTDATMLSGESANGKYPVESVHTMATINKNAQALLKEYGRLDPSTFDRSSKTEVVASAVKEATNSMDI
KLIVALTESGNTARLISKYRPEADILAVTFDELTQKSLMLNWGVIPIVTETPSSTDDMFEVAERVALESGLVESGDNIVI
VAGIPVGSGNTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-73 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-73 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-73 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-73 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STER_1163 YP_820550.1 pyruvate kinase VFG0479 Protein 1e-73 44