Gene Information

Name : leuS (LEUM_0635)
Accession : YP_818121.1
Strain : Leuconostoc mesenteroides ATCC 8293
Genome accession: NC_008531
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 600145 - 602571 bp
Length : 2427 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCATACGATCACAAATCTATTGAAGCCAAGTGGCAAAAATATTGGGATGAACACGAGACGTTTAGGGCTCCTGATAA
ATCAGAAAAAGAAAAGTACTACGTTATGGATATGTTCCCCTATCCTTCTGGACAAGGATTACATGTTGGGCATCCCGAGG
GGTATACAGCGACTGATATTATGAGTCGTTATAAGCGTGCTAAAGGTTTCAATGTTTTGCATCCAATGGGATGGGACGCA
TTTGGATTACCTGCGGAACAATACGCAATTAAAACAGGTAATAATCCAGCAGGCTTCACCAACAAAAATGTCCAAGTGTT
TAAAAATCAAATTAAGTCACTTGGCTTTTCAATTGATTGGTCGCGTGAAATCAATACAACTGATCCTGAATATTATAAGT
GGTCACAATGGATTTTTGAAAAGTTATACGAAAAAGGCTTAGCCTACGAAGATGAAATCATGGTTAACTGGGCTCCAGAT
TTTCCAGGTGGGGGTATTGTTGTTGCCAACGAAGAAGTCATTGATGGTAAGACAGAACGTGGTGGTTATCCAGTTTACCG
CAAGCCAATGAAACAATGGGTTTTGCGCATTACAGCTTATGCCGATCGTTTACTTGAAGATTTGGAAGATTTAGATTGGC
CAGAAGCTATTAAGGAACAACAACGTCACTGGATTGGGAAGTCAATTGGTGCTTCTGTATTCTTCAATATTGCAGATTCA
GACAAACAAATTGAAGTTTATACCACACGACCAGATACGTTGTTTGGTGCCCAGTATATGGTTCTATCACCAGAACATGA
ACTGGTAGATGAAATCACTACGCTAGAGCAAAAAGAAGCCATTGCCAACTATAAAAAAGAGGTAGAAACTAAATCTGATT
TGGAACGAACAGATTTGAACAAAGATAAGACCGGAGCCTTTACAGGTGCTTATGCTACTAATCCAATCAATGGTGAGAAG
TTACCTATTTGGATTGCTGACTATGTTTTGTCTTCTTACGGTACTGGTGCTATCATGGCTGTTCCAGCACACGATGATCG
TGATTGGGAATTTGCTAAAAAGTTCAATTTACCAATTAAAGCTGTTATTGAAGGTGGCAATGTTGAAGAAGCTGCTTACA
CTGACGATGGTACGCATATTAATTCTGGCTTCTTAGATGGGTTAAATAAGCAAGAAGCCATCGATAAAGCTATTAGTTGG
TTGGAAGAACATAATGCTGGTCATCAACAAATTAACTATCGCTTGCGTGATTGGATCTTTTCACGTCAACGTTATTGGGG
TGAACCTATTCCAGTTATTCATTGGGAAGATGGTACACAAACCCTCGTTCCTGAATCAGAATTGCCATTGCGTCTACCAG
AAATGACACAAGAACAATTAAAACCTTCTGGAACGGGAGAATCACCATTAGCTAATGCTACTGATTGGCTAAATGTTACT
CGTAAAGATGGTGTTAAGGGGCGTCGTGAGACCAATACTATGCCGCAGTGGGCTGGTTCATCATGGTATTTCCTACGTTA
TGTTGATCCGCATAATTCAGAGGCATTGGCTGATCCTGAAAAGTTAAAGTACTGGATGAATGTTGATTTGTACGTAGGTG
GTGCAGAACACGCTGTTTTGCATTTATTGTATGCACGTTTTTGGCACAAGTTCTTATATGACTTAGGTGTTGTACCAACT
AAAGAGCCATTCCAAAAATTAGTTAACCAAGGCATGATCTTAGGTGAAAACCACGAGAAAATGTCTAAATCTAAGGGGAA
TGTTGTTAATCCTGATGAAATTGTTAACAATTATGGCGCAGATACATTACGTGTATATGAAATGTTCATGGGGCCATTGA
CACAAAGCAAGCCTTGGTCTGAAGATGGCGTTTCCGGATCGCGTCGTTGGTTGGATCGTGTATGGCGTCTGCTAGTTGAT
GAGGAAGATAAGTTACGTGACCATGTAACAACGGTCAACAAAGGGGACTTAGATAAAATCTATCATCAAACAGTTAAAAA
AGTTTCGGAAGATTTGGAGAATATGCGATTTAACACAGCTATTTCTCAATTAATGGTTTTTGTTAATGAAGCATATAAAT
CAGAAGCTTTACCTGTCCAGTATATGGATGGTTTTGTTCAAATGTTGGCGCCGATTGCACCACACTTAGCTGAAGAACTA
TGGTCAAAACTTGGACATGAAGAGGATATTAGTTACGTTTCATGGCCAACTTATGATGAAAGTCAGCTTGTTGAAGATAG
TGTGGAAATTATTTTCCAAGTGAATGGTAAAGTGCGTGGTAAAGCCACTGTTGCTCGTAACATTGATAAAGATGCTATGC
TCGACTATGCTAAGGCTGATGAAAATGTCCAGAACTTTATTTCTGGTAAGGAAATTCGCAAAATAATTGCTATTCCTGGT
AAGTTTGTTAATATTGTGGTAGGTTAA

Protein sequence :
MAYDHKSIEAKWQKYWDEHETFRAPDKSEKEKYYVMDMFPYPSGQGLHVGHPEGYTATDIMSRYKRAKGFNVLHPMGWDA
FGLPAEQYAIKTGNNPAGFTNKNVQVFKNQIKSLGFSIDWSREINTTDPEYYKWSQWIFEKLYEKGLAYEDEIMVNWAPD
FPGGGIVVANEEVIDGKTERGGYPVYRKPMKQWVLRITAYADRLLEDLEDLDWPEAIKEQQRHWIGKSIGASVFFNIADS
DKQIEVYTTRPDTLFGAQYMVLSPEHELVDEITTLEQKEAIANYKKEVETKSDLERTDLNKDKTGAFTGAYATNPINGEK
LPIWIADYVLSSYGTGAIMAVPAHDDRDWEFAKKFNLPIKAVIEGGNVEEAAYTDDGTHINSGFLDGLNKQEAIDKAISW
LEEHNAGHQQINYRLRDWIFSRQRYWGEPIPVIHWEDGTQTLVPESELPLRLPEMTQEQLKPSGTGESPLANATDWLNVT
RKDGVKGRRETNTMPQWAGSSWYFLRYVDPHNSEALADPEKLKYWMNVDLYVGGAEHAVLHLLYARFWHKFLYDLGVVPT
KEPFQKLVNQGMILGENHEKMSKSKGNVVNPDEIVNNYGADTLRVYEMFMGPLTQSKPWSEDGVSGSRRWLDRVWRLLVD
EEDKLRDHVTTVNKGDLDKIYHQTVKKVSEDLENMRFNTAISQLMVFVNEAYKSEALPVQYMDGFVQMLAPIAPHLAEEL
WSKLGHEEDISYVSWPTYDESQLVEDSVEIIFQVNGKVRGKATVARNIDKDAMLDYAKADENVQNFISGKEIRKIIAIPG
KFVNIVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65