Gene Information

Name : LEUM_0182 (LEUM_0182)
Accession : YP_817686.1
Strain : Leuconostoc mesenteroides ATCC 8293
Genome accession: NC_008531
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 155266 - 156573 bp
Length : 1308 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATACGTTATATGCGTAAAAACAGCGCAGAAGTCAAGCAACGTTTAGAATACCGTGGCGTTAACCCAGAAAC
AATTGACGAGTTATTGGAACTTGACCAAAAACGACGGGATTTGATCCAAAAAGTTGAGTCTCTTAAAGCACAACGTAATG
ATGTATCAGATAAAATTGCTTTTGCTAAGCGTCAAAAAGAAGATGCTAGTGAAGCAATTTTGCAAATGAAGCAAGTCGGG
GCAGATATTAAGAGTCTTGATAATGAGCAAACATTGCTGGATGAACAGGTTCGAGAAATCGCTGCTCATTTGCCAAACAT
GGCTGCTTTTGATGTACCAGTTGGGCCAGATGAATCTGCTAACGTAGAACAACGAAAGTGGGCCCCAGAGGAATATGGAT
CACGTCCGCATGCCTTAGAAGAAGCATCGTGGGTTAAAGCTCATTATGAAATTGGAGAGAATCTGGGGATACTTGACTTT
GAGAGAGGCGCAAAAGTTTCTGGTGCCCGCTTCTTATACTACGTTGGTGATGGGGCAAGGCTTGAACGTGCTGTCTATAA
CTTTATGTTAGATGAGCATAGGCAAGAAGGTTACACTGAAATGATCACGCCGATTGTGGTGAATGATTCAGCAATGTTTG
GAACAGGACAATATCCAAAGTTTCAAGATGATGCTTATCGTGTAGAAGGATTGAATCAAACATATATTCCAACAGCGGAA
GTCCCTTTGACTAACTATTATTCAGGTGAAGAATTGCCAAGTGAGGACTTACCAATCAAGTTCACTGCGCTGTCACCTTC
TTTCCGTAAAGAAGCGGGATCGGCAGGTAAAGATACGCGTGGATTAATCCGTTTGCATCAATTTAATAAGGTTGAAATGG
TTAAATTTACCAAACCAGAAGATTCTTACGAAGAATTAGAAAAGATGACACTAGATGCGGAAAACATTTTACAAAAATTG
AATTTGCCTTATCATGTGATTGTATTGTCAACAGGCGACATGGGATTCTCAGCAGCAAAAACATATGATATTGAGGTCTG
GATGCCACAGCAGAACGTTTATCGAGAAATTTCTTCAGTATCAAACACTGAAGATTTCCAAGCCCGTCGAATGCACATTA
CCTATCGTGATGCAGATAATAAGTTACAGCTTGTGCATACATTAAATGGTTCTGGTCTAGCAGTAGGGCGAACAGTAGCG
GCTATTTTAGAAAACTATCAAAATGAGGATGGTTCAGTAACTATTCCAGAAGTTTTGCGACCTTATTTAGCCGGACAAGA
GAAGCTTGAACCAACAACACACCATTAA

Protein sequence :
MLDIRYMRKNSAEVKQRLEYRGVNPETIDELLELDQKRRDLIQKVESLKAQRNDVSDKIAFAKRQKEDASEAILQMKQVG
ADIKSLDNEQTLLDEQVREIAAHLPNMAAFDVPVGPDESANVEQRKWAPEEYGSRPHALEEASWVKAHYEIGENLGILDF
ERGAKVSGARFLYYVGDGARLERAVYNFMLDEHRQEGYTEMITPIVVNDSAMFGTGQYPKFQDDAYRVEGLNQTYIPTAE
VPLTNYYSGEELPSEDLPIKFTALSPSFRKEAGSAGKDTRGLIRLHQFNKVEMVKFTKPEDSYEELEKMTLDAENILQKL
NLPYHVIVLSTGDMGFSAAKTYDIEVWMPQQNVYREISSVSNTEDFQARRMHITYRDADNKLQLVHTLNGSGLAVGRTVA
AILENYQNEDGSVTIPEVLRPYLAGQEKLEPTTHH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-129 65