Gene Information

Name : leuS (LGAS_0459)
Accession : YP_814295.1
Strain : Lactobacillus gasseri ATCC 33323
Genome accession: NC_008530
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 486733 - 489147 bp
Length : 2415 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGTACAATCACAAAACCGTAGAAAAAAAGTGGCAAAAATATTGGGCAGAGCATGATACTTTTAAGACAGGAAATGATCC
TAAGAAGAAAAATTATTATGCTTTAGATATGTTCCCATTTCCATCTGGCAAGGGACTTCATGTAGGACACCCAGAAGGCT
ATACTGCAACTGACATTATCTCTAGAATGAAGCGAGCACAAGGTTATAATGTGCTTCATCCGATGGGATGGGATGCTTTT
GGCCTGCCAACAGAACAATACGCATTAAAGACTGGTGAAGATCCAGAAAAAGTTACTAAAGAAAATATTGCTAACTTTAA
AAAACAACTTAATAAGCTTGGCTTTTCATATGATTGGGATCGCGAAGTAACAACTTCTGACCCTAATTACTACAAGTGGA
CCCAATGGGTTTTTGAACAAATGTACAAAAAAGGTTTAGCTTATGAAGCTGAAGTTCCTGTTAACTGGTCACCAGATTTA
GGAACAGTTGTTGCCAATGAAGAAATCGTTGATGGTAAAACTGAACGTGGTGGTTACCCAGTTTACCGTCGTAATATGCG
TCAGTGGATGCTTAAGATGACTGCTTATGCAGATCGCTTACTTGAAGATCTAGACGATTTAGATTGGCCAGAACCGGTTA
AAGAAATGCAACGTAACTGGATTGGTCGTTCAGAAGGTGCACAAGTTACTTTTAAGGTTAAAGATAGTGATAAGACTTTT
GATGTCTTTACTACTCGTCCAGATACTTTATTTGGTGTTAGCTACACAGTGCTTGCTCCTGAAAGTAAATTAGTTCAAGA
AATCACTACTCCTGAGCAAAAAGCGGCAGTTGATTCTTACATTAAGAAAATTGAATCTAAGTCTGACCTTGAAAGAACTG
ATTTGAATAAGGATAAGACCGGTGTATTTACAGGTGCTTACGCAATTAATCCTGTTAATGGCAAGGAAGTTCCAGTTTGG
ATTTCTGATTATGTCCTAGCAAGTTACGGTACTGGTGCAGTAATGGCAGTGCCAGCTCATGATGATCGTGATTATGCTTT
TGCTACTAAATTTGGTTTACCAATTAACCGAGTTATTGAAGGCGGAGATTTAGAAAAAGAGGCTTTCACTGGTAATGGTA
AGCATATTAATTCGGACTTCTTAGACGGCCTAGATAATGAAGAAGCTAAGAAGAGAATGATTGAATGGCTTGAAGATCAC
AATGCTGGTCAAAAGAAGGTTAACTATAAACTTCGTGACTGGGACTTTTCTCGTCAACGCTACTGGGGTGAACCAATTCC
TGTTATTCATTGGGAAGATGGCACTACTTCATTAGTTCCTGAAGATGAATTACCACTTCGTCTGCCACATGCAACTGACA
TTAAGCCATCTGGTACTCCAGAAAGCCCACTTGCTAACTTAACTGACTGGGTAAATGTTGTTGATAAAAATGGTCGAAAA
GGTAAGCGTGAAACTAATACGATGCCTAACTGGGCTGGTTCTTCTTGGTACTACTTACGGTATATTGATCCGCACAATGA
TAAAGAATTAGCAGATTATGACTTACTTAAAAAATGGCTTCCAGTAGACCTTTATATTGGTGGTGCAGAACACGCAGTTC
GTCACCTTCTTTACGCTAGATTCTGGCACAAGGTACTTTATGACTTAGGTGTTGTACCAACCAAGGAACCATTCCAACGT
TTGTATAACCAAGGCTTGATTTTGAAGAATCACGAAAAGATGTCTAAGTCTAAGGGTAACGTAGTTAATCCAGACGATGT
GATTGATGAATATGGTGCCGACTCACTTAGAATGTATGAAATGTTCATGGGCCCACTTGATGCTTCAATCGACTGGGATG
ACAATGGTCCAGCTTCAACTAAGAAGTTCCTAGATCGCGTATGGCGTCTATTTGTTAACGATCTCGACTTAAAAGCAATT
CCGCAAGAAAGAATTGTTGACAAAAATGACGGTGAACTTGATAAAGTTTATGCTGAAACCGTTAAGAAAGTTACAGAAGA
TTTTGATGCCTTACACTTTAATACAGCAATTAGTCAAATGATGGTATTTATAAATGCTGCTCAAAAGGCTAAGACTATTC
CACGTGAATATGCTGAAGGTTTTGTTAAGTTGCTTGCTCCAGTGGCACCACACATGATGGAAGAAATTTGGCAAGTCTTT
GGTCATGATGAATCAATCTCTTATGCTAAATGGCCAGAATATGATCCAGCTAAATTAGTTGAATCAACTGTTGAAATTAT
GGTTCAAGTTAATGGTAAACTTCGTGGAAAATTTAAGGCTGCTAAAGATTCTGCTAAAGATGCTTTAGAAAAAGAAGCTC
TTTCTCTTGACCATGTTCAAAAATTCTTAGATGGAAAAGATGTTAAGAAAGTGATTGTTATTCCAAACAAGATCGTTAAC
ATTGTTGCTAAGTAA

Protein sequence :
MYNHKTVEKKWQKYWAEHDTFKTGNDPKKKNYYALDMFPFPSGKGLHVGHPEGYTATDIISRMKRAQGYNVLHPMGWDAF
GLPTEQYALKTGEDPEKVTKENIANFKKQLNKLGFSYDWDREVTTSDPNYYKWTQWVFEQMYKKGLAYEAEVPVNWSPDL
GTVVANEEIVDGKTERGGYPVYRRNMRQWMLKMTAYADRLLEDLDDLDWPEPVKEMQRNWIGRSEGAQVTFKVKDSDKTF
DVFTTRPDTLFGVSYTVLAPESKLVQEITTPEQKAAVDSYIKKIESKSDLERTDLNKDKTGVFTGAYAINPVNGKEVPVW
ISDYVLASYGTGAVMAVPAHDDRDYAFATKFGLPINRVIEGGDLEKEAFTGNGKHINSDFLDGLDNEEAKKRMIEWLEDH
NAGQKKVNYKLRDWDFSRQRYWGEPIPVIHWEDGTTSLVPEDELPLRLPHATDIKPSGTPESPLANLTDWVNVVDKNGRK
GKRETNTMPNWAGSSWYYLRYIDPHNDKELADYDLLKKWLPVDLYIGGAEHAVRHLLYARFWHKVLYDLGVVPTKEPFQR
LYNQGLILKNHEKMSKSKGNVVNPDDVIDEYGADSLRMYEMFMGPLDASIDWDDNGPASTKKFLDRVWRLFVNDLDLKAI
PQERIVDKNDGELDKVYAETVKKVTEDFDALHFNTAISQMMVFINAAQKAKTIPREYAEGFVKLLAPVAPHMMEEIWQVF
GHDESISYAKWPEYDPAKLVESTVEIMVQVNGKLRGKFKAAKDSAKDALEKEALSLDHVQKFLDGKDVKKVIVIPNKIVN
IVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 65