Gene Information

Name : LGAS_0283 (LGAS_0283)
Accession : YP_814127.1
Strain : Lactobacillus gasseri ATCC 33323
Genome accession: NC_008530
Putative virulence/resistance : Virulence
Product : ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 318784 - 321300 bp
Length : 2517 bp
Strand : +
Note : -

DNA sequence :
TTGTCTAAAGATTGTAGTATGATCTTAAAAGAAATAAGGCGGTGCAGAATGGAAAAATCATATAGTGATAGTGCAAAGAA
TGTTCTTGAAATTGCTAAAGAGCAAGCACAAAACTTTCACCATCGAATTATTGGAACGGAGCATGTTTTGCTTGCTTTAG
TAATTGAAGCTAACGGAGATGCCGGTAAGCTTTTGCGTGAAAGAAACGTAACACCAACCTTAGTGCGAGAAGAAATTGAA
AGATATACTGGCTATGGTTCAAGTCCCAAAGCTACATATATGGAAATGTCACCACGCTTAAGCTTAGTTTTGAATTTTGC
TAAGCAAAAATCTGATGAATTAGGCACTCCTCAAATTGAAACAAAGCATATTTTGCTGGGGTTATTAGCTAGTGACCAAA
TTTTGGCAAGTTTAATTTTGAAAAATATTGGTGTAGAACCACGTGACTTAAGTCAAGATATTAATGATAGTTTCATGGAT
GATTCTGGAGAAGCAAACAATATTTTTGATGTTTCTTCTGCAACTAGAACTAAAAAAGGCAAGTCACTGACACCTAATTT
AGATAAAGTAAGTGTAAATTTAAATAAACGTGCACGCGAGGGTGCAATTGATCCAGTAATTGGTAGAGATAAAGAAATAA
AGCGAGTAATTCAAATTTTATCTCGAAGAACTAAGAATAATCCTGTTTTAGTTGGAGAACCCGGAGTTGGTAAGACAGCA
GTTGCACAAGGAATAGCTTCTGCAATTGTAAATCGTGAGGTTCCGGATAACTTAGCTAAAAAACGTGTCATGGCACTAGA
TATGGGAAGTCTAATTGCTGGGACTAAATATCGCGGTGAATTTGAAGATAGAATGAAGAAAATTCTAAAAGAAATTCAAC
GAGATGGTTCTGTGATTCTATTTGTTGATGAAATGCACACCTTGATTGGTGCAGGTGGAGCAGAAGGTGCCATTGATGCT
TCAAATATCTTGAAGCCATCTTTAGCACGCGGTGATATTCAAATGATTGGTGCCACTACTTTTGATGAATATCAAAAGTA
CATTGAAAAAGATCAAGCTTTGGCAAGACGTTTTCAACAGGTTAAAATTGGCGAACCATCAAAAGAAGAAACAGTGGATA
TCTTAAAGGGATTACGTCCTAAATATGAAAAATTCCACAATGTAAAAATTGAAGATGAAGCAATTAAAGATGCAGTCGAA
TTTTCAACAAGATATATTGCTAACCGCTTTTTACCTGACAAGGCAATTGACTTAATTGATGAGGCGAGTGCAGCAGTCAA
GATTCAAGCAGTTGGTAAGGCTGATCCACGCTTGACTAAGTTAGATACCCAAATTAATGATGTTATTCACCAAAAAGAAG
AGGCAGCTGAAAATCAAAACTTTGTACAAGCAGCTAAATTACGTGATGAAGAAAATAAGCTTACGCAAGATCGGGATAAA
TTAATTGCCAGAGTAGAGAACAAGAACTCTAAAAAATCTATTGTTGATTCAAATAAAATTGCCCAGATTGTATCAGAATG
GACGGGCGTACCAGTTACTCGAATGAAGAAGAGTGAAACGAAACGTTTAGCTCACCTCGAAAGTATTTTGCATGAACGCG
TAATTGGACAAGATAAGGCAATTAGTGCAGTAAGTCGTGCAATTAGACGAAGTAGAAGTGGGATTAAGGATGAGAATCGT
CCAATCGGTTCTTTCTTGTTCTTAGGACCTACTGGGGTCGGTAAGACTGAATTAGCAAAAGCATTGGCAGCAGCAGTCTT
TGGTTCAGAAAGAAATATTATTCGTGTTGATATGTCTGAATATATGGATCAAGTAGCTACAAGCAAGTTAATTGGTTCTG
CTCCTGGTTATGTAGGCTATGAAGAAGGTGGACAACTTTCAGAACGTGTAAGACGTAATCCATATTCAGTAATTCTGTTA
GACGAAGTGGAAAAAGCTCATCCAGATGTTTTCAATTTATTGCTGCAAGTTTTAGATGAGGGTTTCTTAACTGATTCAAA
GGGAAGAAAAGTTGATTTTAGAAATACAATCATTATTATGACTTCTAACCTTGGTTCGCGCAGCTTACAAGAAGATAAGA
CAGTTGGCTTTGCGGCTGATAACGAAGATAAAAATAAACTTCAGCAAGAAAAGGTTACAGCAGCAGTTAAACAGTTCTTT
AGACCAGAATTTTTGAATAGAATTGATGAAACAGTTGTCTTTGATAGTTTAACTAAGAAACAATTGCGTGAAATTGTTAG
TTTAATGACTAGTCATTTGATTAGTCGCTTAGCTCGAAAAGAAGTTACTTTAAAGATTTCTCCAGCAGCTTTAGATGTGT
TAGCCAAAGACGGTTTTGATCCAGAAATGGGAGCCCGTCCTTTGCGCCGTGCAATTCAACATGAACTTGAGGATGTAATT
GCAGAAGATTTAATTAGTGAAAAGATTAAAGCTGGTCAAACAGTTAAAGTTGGTGCTCATCAAGGTAAATTAAAATTTAC
AATTGTTGATAAAGATAAGCCTTTAGTTAAAAACTAG

Protein sequence :
MSKDCSMILKEIRRCRMEKSYSDSAKNVLEIAKEQAQNFHHRIIGTEHVLLALVIEANGDAGKLLRERNVTPTLVREEIE
RYTGYGSSPKATYMEMSPRLSLVLNFAKQKSDELGTPQIETKHILLGLLASDQILASLILKNIGVEPRDLSQDINDSFMD
DSGEANNIFDVSSATRTKKGKSLTPNLDKVSVNLNKRAREGAIDPVIGRDKEIKRVIQILSRRTKNNPVLVGEPGVGKTA
VAQGIASAIVNREVPDNLAKKRVMALDMGSLIAGTKYRGEFEDRMKKILKEIQRDGSVILFVDEMHTLIGAGGAEGAIDA
SNILKPSLARGDIQMIGATTFDEYQKYIEKDQALARRFQQVKIGEPSKEETVDILKGLRPKYEKFHNVKIEDEAIKDAVE
FSTRYIANRFLPDKAIDLIDEASAAVKIQAVGKADPRLTKLDTQINDVIHQKEEAAENQNFVQAAKLRDEENKLTQDRDK
LIARVENKNSKKSIVDSNKIAQIVSEWTGVPVTRMKKSETKRLAHLESILHERVIGQDKAISAVSRAIRRSRSGIKDENR
PIGSFLFLGPTGVGKTELAKALAAAVFGSERNIIRVDMSEYMDQVATSKLIGSAPGYVGYEEGGQLSERVRRNPYSVILL
DEVEKAHPDVFNLLLQVLDEGFLTDSKGRKVDFRNTIIIMTSNLGSRSLQEDKTVGFAADNEDKNKLQQEKVTAAVKQFF
RPEFLNRIDETVVFDSLTKKQLREIVSLMTSHLISRLARKEVTLKISPAALDVLAKDGFDPEMGARPLRRAIQHELEDVI
AEDLISEKIKAGQTVKVGAHQGKLKFTIVDKDKPLVKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-175 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LGAS_0283 YP_814127.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones VFG0079 Protein 0.0 52
LGAS_0283 YP_814127.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones VFG0080 Protein 2e-146 52