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Name : guaA (LGAS_0231) Accession : YP_814078.1 Strain : Lactobacillus gasseri ATCC 33323 Genome accession: NC_008530 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 267163 - 268716 bp Length : 1554 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : GTGGCTAAGACTAATCTAAATGACTTTGACAAGATTATCGTGCTTGATTTTGGTAGTCAATATAACCAACTGATTACCCG TCGAATTCGTGATTTTGGTATTTATTCAGAACTTTTGCCTCATGACTTGAGCATTGAAAAAATTAAGAAAATGGCACCTA AAGGAATTATCTTTTCAGGTGGTCCTAACAGTGTTTATGATGAAGGCGCATTAAAGGTTGATCCTGAAATCTTTAAGCTA GGTATTCCAATTTTAGGTATTTGCTACGGGATGCAGCTGATGAGTTACGACTTAGGTGGCAAGGTAGAAAAGGCTGATAA TTCAGAATATGGCCGTGCAGATATCGAAGTAACTGATCCAAATGCGGTCTTGTTTGAAGGCTTACCTAAAGAGCAATATG TATGGATGAGCCACGGAGATCTAGTAACTAAGGCACCAGAAGGCTTTAAAGTTACTGCTAAGAGTAAGAATTGCCCAATT TCTGCAATTGCTAATGATGAAAAGAAATTCTATGGAATTCAATTCCATGCGGAAGTTCGCAATTCAGAATATGGCTTAGA TATTTTGAAGAACTTTGCATTCAATGTTTGTGATGCAAAGGCTAACTGGACAATGGACGATTTCATTGAAATGCAAGTTG ATGAAATTCGTGAAAAAGTCGGTGATAAGAAAGTCATCTTAGGCCTTTCAGGTGGTGTTGATTCAAGCGTTACAGCAACA CTTTTGCACAAGGCAATTGGCGATCAATTGACTGCAATTTTTGTTGATCATGGGATGCTTCGTAAGGACGAAGGCGACCA AGTAATGCAGGCCTTGAACAAGGATCTTGGTGTAAACATTATTCGTGTTAATGCACAAAAGCGCTTTTTAGATAAACTTA AGGGCGTAACCGACCCTGAGCAAAAACGTAAGATCATTGGTAAGGAGTTTATTGAAGTCTTTAATGAAGAAGCTAAGAAG CTTAAGGATGTTGATTTCTTAGCTCAAGGTACGTTATATACTGATGTGATTGAATCAGGTACTAATACTGCTCAAACAAT TAAGTCTCACCACAATGTTGGTGGCTTACCTGAGGATATGCATTTTGAGTTAATTGAACCACTTCGTAAGCTTTTCAAGG ATGAAGTACGTGAACTGGGTGAAAAATTGGGTATTCCACACGACTTAGTATGGCGTCAACCATTCCCAGGTCCAGGTCTT GCTATTCGTGTATTAGGTGAAGTTACCGAAGATAAACTTAAGATTGTGCGTGAAAGTGACGCAATTTTACGTGATGAAAT TAAAAAGGCTGGCCTGCAAGAAGATATTTGGCAATATTTCACAGTACTTCCTGGTATTCGCTCAGTTGGTGTTATGGGTG ATGGACGTACTTACGACTACACCATTGGTATTCGTGCTGTAACTTCAATTGATGGGATGACTGCAGACTTTGCTAAATTG CCATGGGATGTATTAAGCAAGATTTCTACAAGAATTGTAGATGAATGTGATCATATTAACCGTGTAGTTTATGATATTAC TAGTAAGCCACCTTCCACTATTGAGTGGGAATAA Protein sequence : MAKTNLNDFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIEKIKKMAPKGIIFSGGPNSVYDEGALKVDPEIFKL GIPILGICYGMQLMSYDLGGKVEKADNSEYGRADIEVTDPNAVLFEGLPKEQYVWMSHGDLVTKAPEGFKVTAKSKNCPI SAIANDEKKFYGIQFHAEVRNSEYGLDILKNFAFNVCDAKANWTMDDFIEMQVDEIREKVGDKKVILGLSGGVDSSVTAT LLHKAIGDQLTAIFVDHGMLRKDEGDQVMQALNKDLGVNIIRVNAQKRFLDKLKGVTDPEQKRKIIGKEFIEVFNEEAKK LKDVDFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPEDMHFELIEPLRKLFKDEVRELGEKLGIPHDLVWRQPFPGPGL AIRVLGEVTEDKLKIVRESDAILRDEIKKAGLQEDIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDGMTADFAKL PWDVLSKISTRIVDECDHINRVVYDITSKPPSTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-179 | 70 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 7e-180 | 70 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 7e-180 | 70 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 9e-132 | 51 |
