Gene Information

Name : LGAS_1621 (LGAS_1621)
Accession : YP_815355.1
Strain : Lactobacillus gasseri ATCC 33323
Genome accession: NC_008530
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1582064 - 1583374 bp
Length : 1311 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATAAAGGTAATTCGAGAGAATTTAGACTGGTCAAAGAAGAAATTAGCTACACGTGGAATAAAGCCAGAAGA
ATTAGACAAATTAGTGGCTATTGATAAAGAAAGACGTGAGGCTTTAACTAAGAGCGAGCAATTAAAGCAAAAGCGTAATG
AAGTATCCGATCAAATTGCACAAGCTAAGCGTAATAAAGAAGACGCCAGCGATGCTATTAAGACAATGCGTGAAGTCGGA
AAAGAAATTAAGGATTTAGATAAAGAAGTAGAAGACCTTACTCAAAAACAAAAGTATATTTTACTTCGTTTACCTAACTT
CCCAGCAGATTCAGATCCTATTGGACCAGATGAAAGCTATAACGAAGAGGTTCGTAAATGGAATGAACCAACTAAGTTTG
ATTTTGAACCAAAGCCTCACTGGGAAATTGGTACTGAATTAAATATTTTAGACTGGGATACTGCTGCTAAGGTTTCAGGC
GCCCGTTTTGTTTACTATAAAGGTGCTGGTGCCTTACTTGAGCGTGCAGTTTCAAATTTCTTCTTAGATGAAAATACTAA
AGATGGTTATACTGAAGTGATCCCACCATACTTGGTAAATGATGCTTCTATGCAAGGAACTGGTCAATTCCCTAAATTCA
CTGAAGATGTTTATACAATTGTTGATAATGATGATCCTGATAAGCCACGTGATTTAACTTTAATTCCAACTGCAGAAGTT
CCATTAGTTAACTACTTCCGTGGCAAGATTTTAGATGCAAAGCAATTACCAATTAATGTTACTGCATTCTCTCCAGCGTT
TAGAAGTGAAGCGGGATCTGCAGGACGTGACACTCGTGGATTGATTAGAATGCACGAATTTAGAAAAGTTGAAATGGTAA
AAATTGTTGATGAAGACAGTTCATGGGATGAATTGGAAAAATTAACGCATAATGCTGAACATTTACTTCAAAAGCTCGGC
TTACCATATCATGTTGTTGCCCTTTCAACTGGGGATGCAAGTTTTACTAGTGCTAAAACTTATGACCTTGAAGTATGGAT
GCCAGCTCAAGATAAATATCGTGAAATTTCAAGCTGTTCAAACTGTACAGATTTCCAAGCTCGTCGTAGCTTAATTCGTT
ATCGTGATGAAAATGGTAAGCTTCATTTAGCTCATACTTTGAATGGATCAGGTCTAGCTGTAGGTAGAACTGTAGCAGCT
ATTTTAGAAAATTACCAAAATGAAGATGGAACTGTAAACGTACCCGAAGCATTACAACCATACATGCATGGTATGAAAGT
AATTACTAAAGAACCAAAATTTGGTGAATAA

Protein sequence :
MLDIKVIRENLDWSKKKLATRGIKPEELDKLVAIDKERREALTKSEQLKQKRNEVSDQIAQAKRNKEDASDAIKTMREVG
KEIKDLDKEVEDLTQKQKYILLRLPNFPADSDPIGPDESYNEEVRKWNEPTKFDFEPKPHWEIGTELNILDWDTAAKVSG
ARFVYYKGAGALLERAVSNFFLDENTKDGYTEVIPPYLVNDASMQGTGQFPKFTEDVYTIVDNDDPDKPRDLTLIPTAEV
PLVNYFRGKILDAKQLPINVTAFSPAFRSEAGSAGRDTRGLIRMHEFRKVEMVKIVDEDSSWDELEKLTHNAEHLLQKLG
LPYHVVALSTGDASFTSAKTYDLEVWMPAQDKYREISSCSNCTDFQARRSLIRYRDENGKLHLAHTLNGSGLAVGRTVAA
ILENYQNEDGTVNVPEALQPYMHGMKVITKEPKFGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-127 63