Gene Information

Name : secA (LBUL_0542)
Accession : YP_812618.1
Strain : Lactobacillus delbrueckii ATCC BAA-365
Genome accession: NC_008529
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 510908 - 513310 bp
Length : 2403 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAACATTTTAAAGAAGTTATACAACGCTGATAAAAGAGAACTTAAGCGTTTTGAAAAAATTGCTGACCAAGTAGA
GTCATACGCTGACCAAATGGCCGCTCTCTCTGACGAAGAATTGCAGGCCAAGACGCCGGAATTCAGGAGCCGGATTGAAA
AGGGCGAAAGCTTAGACGACCTGCTGCCGGAAGCCTTTGCCGTATCCCGGGAAGCTTCCAAGCGGGTTCTGGGCCTGTAC
CCATTCCGCGTGCAGATCCTCGGCGGGATTGCCCTGCACCGGGGCAACATTGCCGAAATGATGACCGGGGAAGGTAAGAC
CTTGACGGCCACCATGCCGGTTTACCTCAACGCTTTGTCTGGCAAGGGCGTGCACGTTGTTACTGTCAACGAATACCTGG
CCAGCCGTGACGAAACTGAAATGGGCCAGCTTTACCGCTGGCTGGGCCTGACGGTCGGCTTGAACGTCAGCACCATGTCC
CCGGAAGAAAAGCGGAAAGCTTACGCCTGCGATGTAACTTACTCAACCAACTCTGAACTGGGCTTTGACTACCTCCGGGA
CAACATGGTTGTCTACAAGGAACAAATGGTGCAGCGGCCGCTTAACTACGCCATCATCGACGAAGTTGACTCCATCTTGA
TCGACGAAGCGCGGACGCCTTTGATCATTTCCGGTGAAGCTGAACAAGCCAACGCTGACTACGTCCGGGCTGACCGCTTT
GTCAAGAAGCTGGTGGAAGACAAGAGCGACAATGACGCCGATGACGATGAAGACCACGGCGACTACAAGATCGACTGGCC
AACCAAGACTATTTCCCTGACCAGAACCGGGATCCAGAAGGCCTGCGACCACTTTGGCCTCAAGAACCTTTACGACGTTG
AAAACCAGAAGCTGGTCCACCACATCGACCAAGCTCTGCGGGCCAACTACATCATGCTCAAGGACATCGACTACGTTGTC
CAAGACGGTGAAGTCCTGATCGTTGACTCCTTTACCGGCCGTGTTATGGAAGGCCGCCGCTTCTCAGACGGCCTGCACCA
GGCTATCGAAGCCAAGGAAGGGGTCAAGATCCAGGAAGAATCCCAGACCCAGGCCACAATTACTTACCAGAACTACTTCA
GAATGTACCAGAAGCTGTCCGGGATGACCGGTACGGCCAAGACTGAAGAAGAAGAATTCCGTGAAATCTACAACATGGAA
GTCATCACCATCCCGACCAACCGGCCAGTTATCAGACAGGACATGCCAGACCTGCTCTACCCGACCCTGGACTCCAAGTT
CAAGGCCGTGGTTGACGAAATCAAGGAGCGGCACGCCAAGGGCCAGCCAATCCTGGTCGGCACGGTGTCCATTGAATCTT
CTGAACGCTTGAGCCACATGCTGGACAAGGAACACATCCCGCATGCTGTCTTGAACGCCAAGAACCACGCCAAGGAAGCA
GCCATCATCATGAATGCCGGCCAAAGAGGGGCAGTTACGATTGCCACCAACATGGCCGGGCGTGGGACTGACATCAAGCT
GGGGCCTGGCGTCAAGGAACTGGGCGGTTTGGCCGTAATCGGGACTGAAAGACACGAATCCCGCCGTATCGACAACCAGC
TGCGGGGCCGGTCCGGCCGGCAGGGTGACCCGGGTTACACCCGCTTCTACCTGTCCTTGGAAGACGACTTGATGAAGCGC
TTCGGGGGCGACCGGGTCAAGGACTTCCTTGACCGCCTGTCCGACAATGACGACGACAAGGTCATCGAAAGCCGCCTGAT
CACCCGCCAGGTTGAATCAGCCCAGAAGCGGGTTGAAGGGAACAACTACGACACCCGGAAGCAGACCCTGCAATACGACG
ACGTTATGCGGATCCAGCGTGAAATCATCTACAAGGAACGGATGCAGGTTATCGATGAGCAGCAGTCCTTGAAGAGTGTC
TTGATGCCGATGATCCACCGGACTATCGACCACCAAGTGGACATGTTCACCCAAGGCGACCGGTCGACTTGGCGCCTGGA
CTCCTTGCGCGACTTTATCGTTTCCAGCCTGGCCAGTGAAGAATACGTTGATTCAGAAATTGACTTCAAGACCTTCACGC
CAGATGCTCTTAAGCAGCAGCTTTACCAGCTGGTTGAAGACAACTACCAGGAAAAGGAAGCTGCCCTGGCTGATCCGGAA
CAAATGCTGGAATTTGAAAAGGTGGTTATCCTCCGCGTGGTTGACGAACACTGGACCAACCACATTGACGCCATGGACCA
ATTGCGGCAGTCAATCGGCCTGCGGGGCTACGGCCAGCTGAACCCGCTGGTTGAATACCAGGACTCCGGCTACAACATGT
TTGAAGAAATGATCAGCGACATCGAGTTTGACGTGACTCGCCTCTTCATGAAGGCTCAGATCAGAAACAACTTGAGTCGG
TAA

Protein sequence :
MANILKKLYNADKRELKRFEKIADQVESYADQMAALSDEELQAKTPEFRSRIEKGESLDDLLPEAFAVSREASKRVLGLY
PFRVQILGGIALHRGNIAEMMTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLASRDETEMGQLYRWLGLTVGLNVSTMS
PEEKRKAYACDVTYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIIDEVDSILIDEARTPLIISGEAEQANADYVRADRF
VKKLVEDKSDNDADDDEDHGDYKIDWPTKTISLTRTGIQKACDHFGLKNLYDVENQKLVHHIDQALRANYIMLKDIDYVV
QDGEVLIVDSFTGRVMEGRRFSDGLHQAIEAKEGVKIQEESQTQATITYQNYFRMYQKLSGMTGTAKTEEEEFREIYNME
VITIPTNRPVIRQDMPDLLYPTLDSKFKAVVDEIKERHAKGQPILVGTVSIESSERLSHMLDKEHIPHAVLNAKNHAKEA
AIIMNAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGYTRFYLSLEDDLMKR
FGGDRVKDFLDRLSDNDDDKVIESRLITRQVESAQKRVEGNNYDTRKQTLQYDDVMRIQREIIYKERMQVIDEQQSLKSV
LMPMIHRTIDHQVDMFTQGDRSTWRLDSLRDFIVSSLASEEYVDSEIDFKTFTPDALKQQLYQLVEDNYQEKEAALADPE
QMLEFEKVVILRVVDEHWTNHIDAMDQLRQSIGLRGYGQLNPLVEYQDSGYNMFEEMISDIEFDVTRLFMKAQIRNNLSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 9e-140 42