Gene Information

Name : thyA (OEOE_0782)
Accession : YP_810373.1
Strain : Oenococcus oeni PSU-1
Genome accession: NC_008528
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 730004 - 730963 bp
Length : 960 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAGCCGAAATGAAGAACAATACCTAAACCTTGCCCGACGTATTTTGGAAACCGGGGCCTCGAAAATGGATCGGACCAA
GACTGGAACACACTCGATTTTTGGTGCGCAAATGCGTTTTGATCTCTCTGAGGGGTTTCCTTTGCTGACCAGTAAAAAAG
TCGCATTTGGACGAATTAAATCGGAATTATTGTGGTTCTTGCGCGGTGACAATAATATTCGTTTTCTCCTGCAACACCAC
AATCATATTTGGGACGAATGGCCCTTTAAAAAATGGGTCGAAAGCAATGAGTATAAAGGCCCCGATATGACTGATTTTGG
TTTGCGCACGCAAAAAGATCCAATTTTCGCCGAACAGTATAAAGAGCAAAAGAAAATCTTTGTTGATCGAATTTTAAACG
ATGACGAATTCAGCAAAAAATTCGGAACAATCGGGGATGTTTACGGAAAGCTTTGGCGTCATTGGCCGGATGCCAACGAC
GATGGCAGCGTAGACCAAATAACCCGTTTAATCAATGAAATTAAAGTTAATCCCAACTCCCGTCGTTTAATTTTAACAGC
TTGGGATCCCGAAACAACGCCGTTTGCCACTCTGCCTTCATGTCATGTTATGAGTCAATTTTATGTAGTAGACGGAAAAA
TTAGCCTACAAATGTACCAAAGATCGGCCGATTATTTTTTGGGAGTACCCTTTAACATCGCCAGTTACTCGCTTCTGCTT
TCAATGGTTGCCGCACAAACCGGATTAGAAGTCGGTGAATTTATTCATACGATTGGTGATGCCCATATTTACAACAACCA
CGTTGACCAAATTAAAGAGCAGTTGTCAAAACCAACACATAAACTTCCGACTCTGAAGCTTAATCCAGACGTGAAGTCAA
TTTTCGATTATGAAATGAGCGATATTAAACTTGAGAATTATATTCACGAAGATGTAATTAAAGCTCCGATCGCTGTTTGA

Protein sequence :
MSRNEEQYLNLARRILETGASKMDRTKTGTHSIFGAQMRFDLSEGFPLLTSKKVAFGRIKSELLWFLRGDNNIRFLLQHH
NHIWDEWPFKKWVESNEYKGPDMTDFGLRTQKDPIFAEQYKEQKKIFVDRILNDDEFSKKFGTIGDVYGKLWRHWPDAND
DGSVDQITRLINEIKVNPNSRRLILTAWDPETTPFATLPSCHVMSQFYVVDGKISLQMYQRSADYFLGVPFNIASYSLLL
SMVAAQTGLEVGEFIHTIGDAHIYNNHVDQIKEQLSKPTHKLPTLKLNPDVKSIFDYEMSDIKLENYIHEDVIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 2e-88 58