Gene Information

Name : guaA (OEOE_1123)
Accession : YP_810686.1
Strain : Oenococcus oeni PSU-1
Genome accession: NC_008528
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1055205 - 1056758 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGATAGAACTTGAAAAAAAATATGATAAGATCCTTGTCCTTGATTACGGTAGCCAATATAATCAGCTGATTACTCGCCG
AATTCGCGAGTTTGGTGTTTTTTCAGAACTGAAATCAAGAAAAATGACAATTGATGAAATTAAGGATTATGTTCCAAAAG
CAATAATTCTTTCCGGGGGGCCAAAATCAGTTTATGCCGATGACGCTTTTACGATTGATCCGGAAATTTTTAGATTGGGA
ATCCCGATTCTTGGTGTTTGTTACGGCATGCAGTTAATGGCTTATGTTTTGCCTGGCGGAAAGGTTCTTCCTAATGATGG
CAACGGCGAATTTGGTCAGGCTGCTCTGCATTTTGATGAAAATTCGCTTTTGTTTGCTAATACGCCGGAAGGACAGAAAG
TACTGATGAGCCACGGAGACTCGGTTGAAGCGGTACCGGAAGGTTTTGTCGTTGCGGCTAAGACGGATAAGACAAAAATT
GCCGCTATTGCCGATGACGATAAGAAACTTTACGGTGCCCAGTTTCATGCCGAGACGACCTTATCCGAGTATGGGAATCA
AATTTTAAAGAATTTTGTTTTTAAAATCGCCCAATGCCAAGCAAATTGGCAAATGAAAGATTTTATCAATGACCAAATTG
AGAAGATCCGCACTGAAGTCGGCAATAAAAAAGTTCTTTTAGGTCTCTCAGGTGGAGTCGACTCTTCCGTAGTGGCTGTT
TTACTTCACAAGGCAATTGGCCGGCAATTGACCTGCATTTTTGTAGATCATGGTTTATTGAGAAAAAATGAGGCCAAACT
GGTAATGGAATCATTAGCCGGTAAATTTGGCTTAAACATTATAAAAGTCGATGCTCAAAAACGTTTTTTGGATAAATTAG
AGGGAATCAGCGAACCTGAGCAAAAACGGAAAATTATTGGCAAAGAGTTTATCGAAACCTTTAATGATGAAGCGAAAAAG
CTGGATGGGATTGATTTTTTGGCGCAGGGAACTCTTTATACGGATGTAATTGAATCCGGAACCGATACTGCCCAAACAAT
TAAGTCGCATCACAACGTTGGCGGTTTGCCAAAAGAAATGCATTTTAAATTAATCGAACCCCTGCGTACTCTGTTTAAAG
ACGAGGCCCGTAAACTTGGCGAAGAAATGCAAATGCCACATGCTTTGGTCTGGCGTCAACCATTTCCCGGCCCAGGATTG
GCAATTCGAATTTTAGGCGAAATTACAGAAGAAAAGTTGGCTGTTGTGCGTGATTCCGATGCGATTTTGCGCGATGAGAT
TGCCAAAGCCGGTTTAGAAGATTCAGTTTGGCAATACTTTACGATTTTGACCGGTCTGCGCTCGGTCGGTGTCATGGGCG
ATGGTCGGACTTATGACTGGACAATTGCGATTCGGGCAATTACTTCCGTCGATGGCATGACAGCTGATTTTGCCAAACTG
CCATGGGATCTGCTGGGCAAAATTTCTGAACGCATTGTCAACGAAGTTGGTCACATCAACCGCGTAGTCTACGACATCAC
GAGCAAGCCGCCGGCAACGATCGAATGGGAATAA

Protein sequence :
MIELEKKYDKILVLDYGSQYNQLITRRIREFGVFSELKSRKMTIDEIKDYVPKAIILSGGPKSVYADDAFTIDPEIFRLG
IPILGVCYGMQLMAYVLPGGKVLPNDGNGEFGQAALHFDENSLLFANTPEGQKVLMSHGDSVEAVPEGFVVAAKTDKTKI
AAIADDDKKLYGAQFHAETTLSEYGNQILKNFVFKIAQCQANWQMKDFINDQIEKIRTEVGNKKVLLGLSGGVDSSVVAV
LLHKAIGRQLTCIFVDHGLLRKNEAKLVMESLAGKFGLNIIKVDAQKRFLDKLEGISEPEQKRKIIGKEFIETFNDEAKK
LDGIDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPKEMHFKLIEPLRTLFKDEARKLGEEMQMPHALVWRQPFPGPGL
AIRILGEITEEKLAVVRDSDAILRDEIAKAGLEDSVWQYFTILTGLRSVGVMGDGRTYDWTIAIRAITSVDGMTADFAKL
PWDLLGKISERIVNEVGHINRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-162 64
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-163 64
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-163 64
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-120 49