Gene Information

Name : LACR_0371 (LACR_0371)
Accession : YP_808400.1
Strain : Lactococcus lactis SK11
Genome accession: NC_008527
Putative virulence/resistance : Virulence
Product : ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 338398 - 339126 bp
Length : 729 bp
Strand : +
Note : -

DNA sequence :

TTGAAAAACGTAACGCTGTCGATTGAAAAAGGAAAAACGACAGCTATTATTGGAGTCAATGGTTCTGGAAAATCAACGAT
ATTAAAAGCCCTAGGGCGCTTGATTAAAGCAGAAGGTCAGGTTATTTTTGATAATCAGCCCTTAAGCAATCATTCAAATC
GGGAGATTGCTCGCATTTTAGCCCTATTGCCTCAATCAATTACTGCTCCCGCAGATATTACAGTCTATGAGCTTGTTAGT
CTAGGACGTTTCCCACATCAAAAACTGATGCAACAACGTTTATCAAAAGAAGATATTACTTTTATTGAGGAATTAATGAG
GGAAACAAATGTTTGGGATATTCGTGAAAGTAAAGTATCAGAACTTTCTGGTGGGCAAAAACAAAGAGTATTTATCACAA
TGATTTTAGCCCAAGATAGTGAGATTATTTTACTAGATGAACCCACAACATATTTGGATTTAGCTCATCAGTTGGATATT
TTGTGTCTGCTTAAAGATTTAGCGACAAAGCGAAATAAAACCATTGTTTACGTTATTCATGACTTGAACCATGCCGCTCG
TTTTGCCGACAACCTAGTTCTCGTCAAAAATGGGAAAGTGGTCGAGCAAGGGACTGTTGATGACTTATTTACTCAAAAAA
CATTGAAAGAGTGCTTTGGATTGGACGTTACTTTAGGATGTGATACCTTTACCAAAAAATTAATGATTACTGGGGTGAAA
GATGCCTAA

Protein sequence :

MKNVTLSIEKGKTTAIIGVNGSGKSTILKALGRLIKAEGQVIFDNQPLSNHSNREIARILALLPQSITAPADITVYELVS
LGRFPHQKLMQQRLSKEDITFIEELMRETNVWDIRESKVSELSGGQKQRVFITMILAQDSEIILLDEPTTYLDLAHQLDI
LCLLKDLATKRNKTIVYVIHDLNHAARFADNLVLVKNGKVVEQGTVDDLFTQKTLKECFGLDVTLGCDTFTKKLMITGVK
DA

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
iusE	YP_005143742.1	iron ABC transporter ATP-binding protein	Virulence	Not named	Protein	3e-46	47
ciuD	YP_005683346.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	4e-39	46
ciuD	YP_003783391.1	iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	4e-39	46
ciuD	YP_005685432.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	4e-39	46
ciuD	YP_005681255.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	4e-39	46
SPN23F_09560	YP_002510939.1	ferric siderophore ABC transporter ATP-binding protein	Virulence	PPI-1	Protein	8e-42	45
SP_1035	NP_345510.1	iron-compound ABC transporter ATP-binding protein	Not tested	PPI-1	Protein	8e-42	45
DIP0585	NP_938961.1	iron ABC transporter ATP-binding protein	Virulence	Not named	Protein	5e-39	44
fagC	YP_005684488.1	ATP binding cytoplasmic membrane protein	Not tested	PiCp 1	Protein	2e-44	44
fagC	YP_005680307.1	ATP binding cytoplasmic membrane protein	Not tested	PiCp 1	Protein	2e-44	44
fagC	YP_003782430.1	ABC transporter ATP-binding protein	Not tested	PiCp 1	Protein	2e-44	44
fagC	YP_005682397.1	ATP binding cytoplasmic membrane protein	Virulence	PiCp 1	Protein	2e-44	44
fecE	AAL08451.1	ATP-binding protein FecE	Virulence	SRL	Protein	1e-41	43

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
LACR_0371	YP_808400.1	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	BAC0164	Protein	8e-42	43

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
LACR_0371	YP_808400.1	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	VFG0925	Protein	8e-42	45
LACR_0371	YP_808400.1	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	VFG1042	Protein	7e-42	43