Gene Information

Name : LACR_2445 (LACR_2445)
Accession : YP_812001.1
Strain : Lactococcus lactis SK11
Genome accession: NC_008527
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2273003 - 2275636 bp
Length : 2634 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAGATAAGAATAGACTTTTGCTAATTGATGGGTCATCGGTTGCTTTTCGAGCGTTTTTCGCATTATATAATCAGTT
AGATCGGTTCAAAGCACCTAATGGCTTACATACAAATGCCATTTTTGCTTTTCATACGATGTTATCTTCTTTGATGGAAC
GAATTCAACCGACACATGTGTTGATTGCTTTTGATGCGGGGAAAACCACTTTTCGGACGGAGATGTTTGCGGATTATAAA
GGGGGACGTTCAAAAACACCTGATGAGTTTCGCGAGCAACTGCCTTTTATCAAGGAAATGATTGAAAAGTTGGGGATTCG
GCATTATGAGTTGGCAAACTATGAGGCCGATGATATTATCGGAACTTTGGATAAAATGGCTGAAGCGCCTGATGTAAATT
TCGATGTGACCATTGTGACCGGGGACAAGGATATGATTCAGCTGGTCGATGGAAATACACGAGTGGAAATTTCTAAAAAG
GGTGTGGCTGAGTTTGAGGAATTTACGCCTGACTATCTCTTAGAAAAAATGGGACTTACGCCATCTCAATTTATTGATTT
GAAGGCTTTGATGGGCGATTCTTCGGATAATTATCCTGGTGTCACTAAAGTTGGTGAAAAAACGGGTCTTAAACTTTTAC
AGGAATTTGGTTCACTGGAAAATCTTTATGAAAATGTTGAGACGCTAAAAGCCAGCAAGATGAAGGATAATCTAATTGCT
GACAAGGAAATGGCCTTTTTGTCACAGCAATTGGCGACAATCAATACGAAAACTCCTCTTGAAATTGGTTTAGAAGATAC
GCTTTTAAAAGAAAAAAATGTGGCTGAACTGGGCCAATTTTATGATGAAATGGGATTTTCACAATTCAAAAGTAAGTTAT
TAACTGACGGCGGTGGAGAAGTTACTGACGAAACTGTCAGTGAAGAAATTAAGTTTGAAATAGTTACTGACAAAAGTTCA
GTTGCTTCAGTCAATGCTGATGATTTCTTTTATTTGGAAACTTTGGGTGAAAATTATCATCGTGAGCAGATTGTGGCATT
TGCTTGGGGAAATGCTGAGAAAATTTATGTTTCAAAAAATCTGGATTTACTGACAGAAATGAAATTTCCTGAAAATACTT
ATGATTTCAAGAAAAATCGCGTACTTTTGAGCCACTTAAATATTGAATTGCCTCTGGTTAAATTTGATGCTATGCTTGCA
AAATATTTGATTTCTACAACGGAAGATAATAAAATTTCAACCATTGCACGACTTTTTGATGTGGGACATTTGGCCACAGA
TGAGGAAATTTTTGGCAAAGGTACAAAACTTGCTCTACCTGATGATGAGATTTTGTTTGACCATTTGGCTCGTAAAATCA
GAGTTTTAGCTCGTGCCAAAGAAAAAATGATGGCTGAACTTATTGAAAATGAACAAGAACATCTTTTGTCTGATATGGAA
TTGCCATTAGCCGAAGTTTTGGCAAAAATGGAGATTACAGGAATTTCTGTCAGTCAAAATACGCTGGAAGAAATTGGTGC
AGAAAACGAAGAAAAATTGGCTTTGCTGACGCGTGAAATTTATGAGTTGGCTGGTGAAGAATTTAATATTAATTCACCAA
AACAACTGGGAGTGATTTTATTTGAAAAATTGCAATTGCCAGTAGGTAAGAAGACAAAAACGGGTTATTCGACGGCGGTG
GACGTTTTAGAAGACTTGGCTGCTTTATCTCCAGTGGTGGCGAAGATTTTGGAATATCGTCAAATCAATAAAGTACAATC
GACTTATGTTAAAGGCTTGATTCCGCAAATTGCTGATGATGGAAAAATCCATACGCGATATGTTCAGGACTTGACGCAGA
CCGGTCGTTTGAGTTCTGTTGACCCGAATTTGCAAAATATTCCTGTTCGACTGGAAGAAGGACGGAAGATTCGTAAGGCA
TTTGTGCCAAGTCAAGATTCTCTTTTGTTGAGTTCCGACTATTCACAAATTGAATTGCGAGTGCTGGCTCATATTTCTGC
TGATGAGCATTTGATTGACGCCTTTAAACATGGGGCTGATATCCATACGTCAACGTCTATGCGGGTCTTTGGCATTGAAA
AAGCAGAAGATGTCACGGCAAATGACCGCCGAAATGCAAAAGCAGTCAATTTTGGTGTGGTTTATGGAATTTCGGATTTT
GGTTTGGCAAGAAATCTGGGAATTACAAGAAAAGATGCCAAAAATTATATTGAAACTTACTTTGAACGTTATCCTGGTAT
TAAAACTTATATGGAAAATATTGTTCGCGAGGCTAGAGATAAAGGATTTGTTGAGACAATGAGTCATCGTCGTCGTAAGA
TTCCAGATATTAATGCACGTAATTTTAATGTTCGTGGTTTTGCGGAGCGGACGGCAATTAATTCGCCAATCCAAGGATCG
GCAGCGGATATTTTGAAAATTGCAATGATTAATCTGGATAAAGCGCTGACGGAACGTCAATCAAAATCAAAATTATTATT
GCAAGTACACGATGAAATTATTCTAGATGTTCCACTTGAGGAATTAGAAGAGATTCAGGTACTTGTCAAAGAAACAATGG
AAGAAGCAATTGAACTTGCTGTACCATTGAAAGTGGATGAAAATACTGGTAAAACTTGGTATGAAGCCAAATGA

Protein sequence :
MEDKNRLLLIDGSSVAFRAFFALYNQLDRFKAPNGLHTNAIFAFHTMLSSLMERIQPTHVLIAFDAGKTTFRTEMFADYK
GGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDIIGTLDKMAEAPDVNFDVTIVTGDKDMIQLVDGNTRVEISKK
GVAEFEEFTPDYLLEKMGLTPSQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVETLKASKMKDNLIA
DKEMAFLSQQLATINTKTPLEIGLEDTLLKEKNVAELGQFYDEMGFSQFKSKLLTDGGGEVTDETVSEEIKFEIVTDKSS
VASVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKNLDLLTEMKFPENTYDFKKNRVLLSHLNIELPLVKFDAMLA
KYLISTTEDNKISTIARLFDVGHLATDEEIFGKGTKLALPDDEILFDHLARKIRVLARAKEKMMAELIENEQEHLLSDME
LPLAEVLAKMEITGISVSQNTLEEIGAENEEKLALLTREIYELAGEEFNINSPKQLGVILFEKLQLPVGKKTKTGYSTAV
DVLEDLAALSPVVAKILEYRQINKVQSTYVKGLIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKA
FVPSQDSLLLSSDYSQIELRVLAHISADEHLIDAFKHGADIHTSTSMRVFGIEKAEDVTANDRRNAKAVNFGVVYGISDF
GLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRRRKIPDINARNFNVRGFAERTAINSPIQGS
AADILKIAMINLDKALTERQSKSKLLLQVHDEIILDVPLEELEEIQVLVKETMEEAIELAVPLKVDENTGKTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 68