Gene Information

Name : LACR_1456 (LACR_1456)
Accession : YP_809388.1
Strain : Lactococcus lactis SK11
Genome accession: NC_008527
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1377813 - 1379321 bp
Length : 1509 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAATAAACGTGTAAAAATCGTCTCAACTCTTGGACCAGCTGTCGAAATTCGTGGTGGCAAAAAATTTGGTGAAAGCGG
CTATTGGGGAGAATCTCTTGACGTCGAAGCATCAGCAAAAAACATTGCAGCTTTGATTGAGGAAGGCGCTAATGTCTTCC
GTTTCAACTTCTCACACGGTGACCATCCTGAACAAGGTGCTCGTATGGCAACTGTTCACCGCGCTGAAGAAATCGCTGGT
CACAAAGTAGGTTTCTTGCTTGATACTAAAGGTCCTGAAATGCGTACAGAACTCTTCACTGACGGTGCTGATTCAATCAG
CGTTGTTACTGGAGATAAATTCCGTGTTGCAACTAAACAAGGTCTTAAATCAACTCCTGAATTGATTGCCTTGAACGTAG
CTGGCGGACTTGACATCTTTGATGATGTTGAAATCGGTCAAACTATCTTGATTGATGATGGTAAACTTGGTTTGTCATTG
ACTGGTAAAGATGCAGCAACTCGTGAATTCGAAGTTGAAGCACAAAATGATGGTGTTATCGGTAAACAAAAAGGTGTTAA
CATTCCTAACACTAAAATTCCTTTCCCAGCCCTTGCTGAACGTGACGATGCAGATATCCGTTTCGGTCTTTCACAACCTG
GTGGAATTAACTTTATCGCTATCTCATTCGTACGTACTGCAAATGACGTTAAAGAAGTACGTCGTATTTGTGAAGAAACT
GGTAATCCACACGTACAACTCTTGGCTAAAATTGAAAACCAACAAGGGATTGAAAACCTTGATGAAATCATCGAAGCAGC
TGATGGTATCATGATTGCACGTGGTGACATGGGTATCGAAGTTCCATTTGAAATGGTTCCAGTTTACCAAAAATTGATTA
TCAGCAAAGTTAACAAAGCAGGTAAAATTGTTGTAACTGCAACAAACATGCTTGAATCAATGACTTACAACCCACGTGCT
ACACGTTCAGAAATTTCAGACGTATTTAACGCTGTTATTGACGGAACTGATGCTACAATGCTTTCAGGTGAGTCTGCTAA
TGGTAAATACCCACGCGAATCAGTTCGTACGATGGCTACTGTTAACAAAAACGCTCAAACAATGTTGAAAGAATACGGAC
GTCTTCACCCAGAACGTTACGATAAATCAACTGTAACAGAAGTTGTTGCTGCATCAGTTAAAAATGCTGCAGAAGCTATG
GATGTTAAATTGATCGTTGCTTTGACTGAATCTGGTAACACAGCTCGTTTGATTTCTAAACACCGTCCAGATGCTGATAT
CTTGGCTATCACATTTGACGAAAAAGTTGAACGTGGATTGATGATCAACTGGGGTGTTATCCCAATGATGACTGAAAAAC
CTGCATCTACTGATGACATGTTTGAAGTTGCTGAAAAATTTGCATTGGCTTCTGGTTTGGTTGAAGCTGGCGACAATATC
ATCATCGTTGCTGGTGTTCCAGTTGGTACTGGTCGCACTAATACAATGCGTATCCGCACTGTTAAATAA

Protein sequence :
MNKRVKIVSTLGPAVEIRGGKKFGESGYWGESLDVEASAKNIAALIEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAG
HKVGFLLDTKGPEMRTELFTDGADSISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQTILIDDGKLGLSL
TGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIRFGLSQPGGINFIAISFVRTANDVKEVRRICEET
GNPHVQLLAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESMTYNPRA
TRSEISDVFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTMLKEYGRLHPERYDKSTVTEVVAASVKNAAEAM
DVKLIVALTESGNTARLISKHRPDADILAITFDEKVERGLMINWGVIPMMTEKPASTDDMFEVAEKFALASGLVEAGDNI
IIVAGVPVGTGRTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-75 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-76 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-76 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-76 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LACR_1456 YP_809388.1 pyruvate kinase VFG0479 Protein 2e-76 42