Gene Information

Name : LACR_1445 (LACR_1445)
Accession : YP_809377.1
Strain : Lactococcus lactis SK11
Genome accession: NC_008527
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1363978 - 1364916 bp
Length : 939 bp
Strand : -
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAGAATCACAATTGCCGGTGCAGGAGCGATGGGAAGCCGTTTTGGACTTATGCTTCATAAAGGGGGCAACGAAGTGAC
CCTTGTAGATGGTTGGCTTGAACATGTGACTGCAATTAAAGAACATGGCCTACAAGCAAATTTTAATGGTGAAGAAATCA
CTGCTCATCTATCAGTAGAATTACAATCTAATATTTCATCAGAAGAAAAAACAGATTTAATTATTTTATTTACGAAAGCA
ATGCAGTTAGATAAAATGCTTCAGGACATTAAACCTTTAATTGCTGAGCATACAAAAGTTCTTTGCTTACTTAATGGAAT
TGGTCATGAAGATATTATTGAAAAATATGTTTCTAAAAATAATATTTTTATTGGGAATACCATGTGGACTGCAGGTTTAG
AAGGACCAGGAAAAGCAAAACTATTTGGAAATGGTTCTGTTGAACTTCAAAATTTCATTCCTGGCGAAGAAGAAACGGCT
AAAAAACTAGCAAACATTTTATCTGCTTCAGGATTAAATGCTAACTATTCTGATAACATCCATTATTCAATTTACCGAAA
AGCGTGCGTTAATGGGACAATGAATGGACTCTGCACTATTTTGGATACTAATATGGCTGGATTGGGAGCAACAAAACCTG
CTCACGATATGGTTGTTACAATTGTCAAAGAATTTGCGGCAGTTGCAAAACATGAGGAGGTGAATCTTGATATAGATGAG
GTTGTAGAACATGTTGAGACATGTTTTGACCCTGAAACGATTGGCTTACATTATCCTTCAATGTATCAAGATTTGATAAA
TAATAATCGCTTGACAGAGATAGATTACATTAATGGTGCAGTTTCACGTAAAGGGAAAAAATATCAGATAGCTACTCCTT
ACTGTGATTTTTTGACTCAATTAGTTCATAGTAAAGAAGAGTTATTAAAGGCGAAATAA

Protein sequence :
MRITIAGAGAMGSRFGLMLHKGGNEVTLVDGWLEHVTAIKEHGLQANFNGEEITAHLSVELQSNISSEEKTDLIILFTKA
MQLDKMLQDIKPLIAEHTKVLCLLNGIGHEDIIEKYVSKNNIFIGNTMWTAGLEGPGKAKLFGNGSVELQNFIPGEEETA
KKLANILSASGLNANYSDNIHYSIYRKACVNGTMNGLCTILDTNMAGLGATKPAHDMVVTIVKEFAAVAKHEEVNLDIDE
VVEHVETCFDPETIGLHYPSMYQDLINNNRLTEIDYINGAVSRKGKKYQIATPYCDFLTQLVHSKEELLKAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 2e-122 80
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 1e-122 80