Gene Information

Name : LSEI_2517 (LSEI_2517)
Accession : YP_807695.1
Strain : Lactobacillus casei ATCC 334
Genome accession: NC_008526
Putative virulence/resistance : Virulence
Product : ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2496800 - 2499307 bp
Length : 2508 bp
Strand : -
Note : -

DNA sequence :
ATGGACAACTTATTTACCCCTAGTGCTAAAAATGTATTGCTTTTAGCCCAGGAACAAGCGAAGTACTTCCATCATCATGC
TGTTGGGACAGAACATTTGCTCATGGCACTGGTCATGGAAAAAGATGGTATCGCTGGTAAGACGCTGCGTCAGTTAGGGG
TCACTGAAAATGATGTCCATGACGAGATCGAGCGCTTCACAGGGTATGGGACTGTTGATGCCGCTGGTCAAGCTAGTGAT
AGTTATTTGCCTTACTCACCAAAAGGTAAAGAGATTTTGGCGTTTGCAGGTGACGAAGCAAAACGGTTAGGTGCTTTAAA
GATCGGTACCGAGCACGTTTTGCTTGGCTTGCTACGTGAAGATGACATCTTGGCAGCACGGATTTTGCAAAACCTTGGTC
TCAGTCTTTCGAAGACGCGTCAAATGGTCTTCAAGAAGATGGGGATTGCGGACACTGCAGCAAAGCGTCGTCCAATGGCA
CGTGGCGGTGCTCGTCAAGATGGACAAGGTACGCCAACGCTAGATGGTTTGGCGCGGGATTTGACCCAAATGGCGCGCGA
GAATCGGATGGATCCGGTTGTTGGGCGTGACAAAGAAGTACGCCGGCTGATCCAGATTCTGGCACGGCGGACAAAGAACA
ACCCTGTACTGATTGGCGAACCTGGTGTTGGTAAAACTGCAATTGCAGAAGGCTTTGCTGAAAAAATTGTGTCTGGTAAA
GTGCCGGATGACATGGTCAACAAGCGTTTGATGATGCTTGATATGGGCTCACTTGTCGCTGGCACCAAGTATCGTGGTGA
GTTTGAAGATCGGCTGAAGAAGATCATTGATGAAATTTATAAAGATGGCAATGTCATTTTGTTCATTGATGAATTGCATA
CTTTGATCGGTGCTGGCGGTGCAGAAGGCGCTATTGATGCTTCCAATATTTTGAAACCGGCATTAGCTCGTGGTGAATTA
CAATTGATCGGTGCCACGACCTTAGATGAATATCAAAAGTATATTGAAAAAGATGCTGCTTTGGAGCGGCGGTTTGCGAC
GATTCAAGTCGACGAACCAACTGAAGAAGAAGCTGAACAAATTTTGAAGGGCTTGCGTCCTCGTTATGAGGCGCATCACG
GTGTCACGATTACTGACGAAGCGCTGCATCAGGCGGTGGTTTTGTCATCACGGTACATCACGACTCGGTTCTTGCCTGAC
AAGGCAATTGATCTAGTTGACGAAAGTGCGGCGAAGGTTCGCTTGGACAAGGCCAATGTTGAGACGAAGGCCGACAAGCT
TCAGGATGAACTGGCCAAGCTGGTAGCTGATAAAGAAGACGCTATTGACCATCAAGATTTCGAAACGGCTGCGAACATCC
GGACTCAGGAAGCTGATTTAAAAACGAAGTTGGCCGACACGCCTGAACCAGTTAATGAAAGTGGCGTTCGAACTGACATT
AAAGTGACGGGCGACGATGTGGCAGAAGTGGTTTCTCAATGGACCGGTGTGCCAGTCACCCAGTTGCAGAAAAAAGAATC
CGATCGGTTGGTTAACTTGGAGAAGATCCTGCATGAGCGGGTTGTTGGCCAAGACGAAGCAGTTTCCGCCGTCGCGCGTG
CTATCCGGCGTGCTCGTTCTGGTTTGAAAGATCCGACGCGGCCAATTGGTTCCTTCATGTTCCTCGGGCCGACAGGTGTT
GGGAAAACGGAGCTGGCTAAGGCGTTAGCCGAGGCAATGTTTGGTTCTGAAGATGCCATGATCCGGGTTGATATGTCTGA
GTACATGGAGAAATTTAGTACCAGTCGGTTGATCGGCGCGGCCCCTGGTTATGTTGGTTACGACGAAGGCGGTCAACTAA
CCGAAAAAGTCCGCAACAAGCCTTACTCGGTTGTGTTGTTGGACGAAGTTGAAAAGGCGCATCCAGATGTCTTTAACATT
TTGCTGCAAGTGCTGGATGATGGCTATTTAACCGATTCAAAAGGTCGGCGGGTTGATTTCCGTAACACGATTTTGATCAT
GACCAGTAATATCGGCGCAACCGCTATTCGTGACGATAAGACTGTTGGCTTTGGTGCCAAGGATCCACAAGCTGACTTTA
ATGCCATGAAGAGCCGGATGCTGGACGAACTTAAAAAAGCGTTCCGACCAGAATTCCTTAACCGAATTGATGAAACCGTG
GTCTTCCACAGTCTCAACAAGGCTGAGCTGCATGAAATCGTTAAGATCATGACGAAGACAGTGCTTAGTCGCATTAAGGA
TCAAGGGATTGACGTTAAAATTACCCCAGCCGGTATTGACGCTGTCGCCGCTGCCGGCTTCGATCCAGAGTACGGTGCAC
GTCCAATTCGGCGGGCACTGCAAACCGGTGTCGAAGATCAGTTAAGTGAACTCTTATTGACAGGCCAAGCTAAAACCGGT
GACTTGATCCAAATCGGTGCTAAAAAAGGCAAGCTGACATTTACTGTTAAAGAGAACAAAGGCAAGCAAAAAGAAAACGG
TGCTTCAAAAGAACCCGTTAAAGCCTAG

Protein sequence :
MDNLFTPSAKNVLLLAQEQAKYFHHHAVGTEHLLMALVMEKDGIAGKTLRQLGVTENDVHDEIERFTGYGTVDAAGQASD
SYLPYSPKGKEILAFAGDEAKRLGALKIGTEHVLLGLLREDDILAARILQNLGLSLSKTRQMVFKKMGIADTAAKRRPMA
RGGARQDGQGTPTLDGLARDLTQMARENRMDPVVGRDKEVRRLIQILARRTKNNPVLIGEPGVGKTAIAEGFAEKIVSGK
VPDDMVNKRLMMLDMGSLVAGTKYRGEFEDRLKKIIDEIYKDGNVILFIDELHTLIGAGGAEGAIDASNILKPALARGEL
QLIGATTLDEYQKYIEKDAALERRFATIQVDEPTEEEAEQILKGLRPRYEAHHGVTITDEALHQAVVLSSRYITTRFLPD
KAIDLVDESAAKVRLDKANVETKADKLQDELAKLVADKEDAIDHQDFETAANIRTQEADLKTKLADTPEPVNESGVRTDI
KVTGDDVAEVVSQWTGVPVTQLQKKESDRLVNLEKILHERVVGQDEAVSAVARAIRRARSGLKDPTRPIGSFMFLGPTGV
GKTELAKALAEAMFGSEDAMIRVDMSEYMEKFSTSRLIGAAPGYVGYDEGGQLTEKVRNKPYSVVLLDEVEKAHPDVFNI
LLQVLDDGYLTDSKGRRVDFRNTILIMTSNIGATAIRDDKTVGFGAKDPQADFNAMKSRMLDELKKAFRPEFLNRIDETV
VFHSLNKAELHEIVKIMTKTVLSRIKDQGIDVKITPAGIDAVAAAGFDPEYGARPIRRALQTGVEDQLSELLLTGQAKTG
DLIQIGAKKGKLTFTVKENKGKQKENGASKEPVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LSEI_2517 YP_807695.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones VFG0079 Protein 0.0 61
LSEI_2517 YP_807695.1 ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones VFG0080 Protein 2e-146 48