Gene Information

Name : leuS (PEPE_0645)
Accession : YP_804150.1
Strain : Pediococcus pentosaceus ATCC 25745
Genome accession: NC_008525
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 685858 - 688275 bp
Length : 2418 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCTTATAATCATAAAGATATCGAACAGAAGTGGCAGCAATTCTGGAGCGACAATGAGACTTTTAAGACGGTCGAAGA
TGCAGACAAACCCAAATATTATGCATTAGACATGTTCCCTTATCCATCAGGTCAAGGACTCCATGTGGGCCATCCTGAAG
GATATACAGCAACAGATATTATGTCACGAATGAAACGTATGCAAGGTTACAAAGTACTTCATCCAATGGGATGGGATGCT
TTTGGTCTTCCAGCAGAACAATATGCGATGAAGACGGGTAACAATCCGCGTGATTTTACAGCTAAGAATATTCAAAACTT
TAAGCGTCAAATCCAATCACTTGGTTTTTCTTATGACTGGTCGCGAGAAGTTAATACAACTGATCCAGCTTACTACAAGT
GGACTCAATGGATTTTTGAGCAACTCTACAAGAAGGGCTTAGCTTATGAAAAAGAAACGCTGGTAAACTGGGCTCCTGAT
TTAATGGGTGGAACGGTAGTTGCTAACGAAGAAGTTGTGGATGGTAAGACAGAACGTGGTGGGTTCCCCGTTTATCGTAA
ACCAATGAAACAATGGATTCTTAAAATTACAGCTTACGCCGACCGTTTGATTGACGATTTGGACCTGGTAGATTGGCCCG
ATAGTATTAAAGAAATGCAAAAAAACTGGATTGGTCGTTCAGTGGGGGCTAGCGTCTTCTTTAATGTTGAAGATAGCGAA
AAACAAATTGAAGTATTTACAACGCGTCCAGATACATTATTTGGCGCAACATACTTGGTAATTTCACCAGAACATGACCT
CGTTGACCAAATTACAACTCCAGAAAGTAAAGCTGCCGTTGAAGAATACAAGAAAGCTGTTGCAACTAAATCAGATCTTG
AACGGACGGATTTGAATAAAGACAAGACGGGAGTCTTCACGGGAGCATACGCGGTTAACCCTGTTAATGGTAAGAAAATT
CCAGTTTGGATTAGTGATTACGTATTGGCTTCATACGGAACTGGAGCAGTGATGGCTGTTCCTGCTCATGATGGCCGTGA
CTACGAATTTGCTAAGAAATTCAAGATAGATATGGTGCCAGTTTATGAAGGTGGCAATCTTGAAGATGGAGTATTGGACA
GCGAAGGCGGGCTAATTAACTCTGGATTCCTAGATGGGATGGATAAGCAGACGGCTATTGATACCATGATTAGCTGGTTG
GAAGAACATGGAGTTGGTCATAAGAAGGTTAACTATCGTCTTCGTGACTGGGTCTTCTCTCGCCAACGCTACTGGGGTGA
ACCAATCCCTGTAATTCATTGGGAAGATGGAGAAACAACTTTGATTCCTGAAGATGAATTGCCATTGAGACTCCCAGCTG
CAACTGACATTCGTCCTTCCGGTACCGGAGAAAGCCCATTAGCTAATTTAGATGATTGGGTAAACGTAGTTGATGAAAAT
GGACGTAAGGGTCGCCGGGAAACTAATACAATGCCACAATGGGCGGGTAGTTCATGGTACTTCCTCCGTTACGTTGATCC
TAAGAATGATCAAAAGATTGCTGACGAAGATTTACTTAAAGAATGGTTACCAGTCGACTTATATGTTGGTGGAGCTGAAC
ATGCGGTACTTCATTTACTTTATGCACGTTTCTGGCACAAAGTTTTATATGATCTAGGAGTTGTACCAACTAAGGAACCA
TTCCAAAAATTGGTTAACCAAGGGATGATTCTCGGTAGCAATCATGAGAAGATGTCTAAGTCAAAAGGGAACGTGGTTAA
TCCAGATGATATTGTTGAGCGCTTTGGAGCGGATACTTTACGATTATACGAAATGTTCATGGGACCTCTGACAGAATCAG
TCGCCTGGAGTGAAGATGGGCTTAACGGAAGTCGTAAGTGGATTGACCGCGTCTGGCGCTTGATGATTGACGACGAAAAC
CAATTGCGTGATCATATTGTTACTGAAAATGATGGCAGTTTGGATATGATTTATAACCAAACTGTTAAGAAGGTAACTGA
TGATTATGAAAACATGCGCTTTAACACGGCTATTTCACAAATGATGGTCTTTGTTAATGAAGCATACAAGGCTGATAAAC
TTCCAGCAGTATATATGGAAGGATTAGTTAAGATGTTAGCTCCAATTATTCCGCACGTTGCTGAAGAACTTTGGAGTTTG
CTAGGTCACGAAGGTGGTATTTCATACGCTGAATGGCCAACATATGATGAAAGTAAGTTAGTAGAAGCTACAGTTCAAGT
CATTCTACAAGTTAATGGTAAAGTTCGGAGTAAGATTACCGTTGACAAGGATATCGCCAAAGAAGAACTTGAAAAATTAG
CGTTAGCTGATGCTAAGATTCAACAATGGACGGCAGATAAGACTGTTCGTAAGGTAATTGTTATTCCTAACAAGATTGTT
AATATCGTAGTAGGCTAA

Protein sequence :
MAYNHKDIEQKWQQFWSDNETFKTVEDADKPKYYALDMFPYPSGQGLHVGHPEGYTATDIMSRMKRMQGYKVLHPMGWDA
FGLPAEQYAMKTGNNPRDFTAKNIQNFKRQIQSLGFSYDWSREVNTTDPAYYKWTQWIFEQLYKKGLAYEKETLVNWAPD
LMGGTVVANEEVVDGKTERGGFPVYRKPMKQWILKITAYADRLIDDLDLVDWPDSIKEMQKNWIGRSVGASVFFNVEDSE
KQIEVFTTRPDTLFGATYLVISPEHDLVDQITTPESKAAVEEYKKAVATKSDLERTDLNKDKTGVFTGAYAVNPVNGKKI
PVWISDYVLASYGTGAVMAVPAHDGRDYEFAKKFKIDMVPVYEGGNLEDGVLDSEGGLINSGFLDGMDKQTAIDTMISWL
EEHGVGHKKVNYRLRDWVFSRQRYWGEPIPVIHWEDGETTLIPEDELPLRLPAATDIRPSGTGESPLANLDDWVNVVDEN
GRKGRRETNTMPQWAGSSWYFLRYVDPKNDQKIADEDLLKEWLPVDLYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP
FQKLVNQGMILGSNHEKMSKSKGNVVNPDDIVERFGADTLRLYEMFMGPLTESVAWSEDGLNGSRKWIDRVWRLMIDDEN
QLRDHIVTENDGSLDMIYNQTVKKVTDDYENMRFNTAISQMMVFVNEAYKADKLPAVYMEGLVKMLAPIIPHVAEELWSL
LGHEGGISYAEWPTYDESKLVEATVQVILQVNGKVRSKITVDKDIAKEELEKLALADAKIQQWTADKTVRKVIVIPNKIV
NIVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 66