Gene Information

Name : thyA (PEPE_1070)
Accession : YP_804568.1
Strain : Pediococcus pentosaceus ATCC 25745
Genome accession: NC_008525
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1066273 - 1067223 bp
Length : 951 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCTTGAAGAACAATACCTTAATTTGGAAAGATATGTTTTGGAAAATGGGCATCTCAAAGGAGACCGTACCCAAACTGG
TACCCTAAGTACTTTTGGATATCAAATGCGTTTTGATTTAAGTGAAGGTTTTCCATTACTAACGACCAAGAGAGTCCCTT
TTGGTTTGATTAAGAGTGAGTTACTCTGGTTTTTAAAAGGCGATACCAATATTAGATATTTACTTCAACATAATAATCAT
ATTTGGGATGAATGGGCTTTTAAAAAGTGGGTTGAAAGTGATGAATATCAGGGACCAGACATGACCGATTTTGGTCACCG
CTCACTGACTGATCCTGAATTCAATGAACTCTATAAAATTGAAAAACAACGTTTTACAGAACAAATTTTGGAAGATGATA
CATTTTCTGCTAAATATGGTGATCTTGGAAATGTTTACGGTAGCCAATGGCGAGCATGGAAGACTAGTACTGGTGAGACT
ATCGATCAAATTTCAAATGTTATTGATATGATTAAGAATAATCCTAACTCAAGAAGAATGATCGTTTCGGCTTGGAATCC
TGAAGATGTGCCAACCTCAGCATTACCTCCGTGTCATTCACTATTTCAATTTTATGTGGCTGATGGGAAACTTAGCTGTC
AACTGTATCAACGCAGTGGCGATATTTTCTTAGGAATTCCTTTCAATATTGCTAGCTATGCCTTGCTTACAGAATTAATT
GCGAAAGCGACTGGTTTAGAAGTGGGAGAATTTATCCATACCATCGGTGATGCTCACATTTATTCTAATCATCTGGATCA
GGTTAAAGAACAATTAGAACGTACTCCACGTCCGGCTCCTAAATTGAAATTTAAACAAGTGCATGACAGTATCTTTGACT
ATGAACCAGGAGATATTGTGGTTGAAGGATATGATCCTCATCCAACCATTAAAGCACCGGTAGCAGTTTAA

Protein sequence :
MLEEQYLNLERYVLENGHLKGDRTQTGTLSTFGYQMRFDLSEGFPLLTTKRVPFGLIKSELLWFLKGDTNIRYLLQHNNH
IWDEWAFKKWVESDEYQGPDMTDFGHRSLTDPEFNELYKIEKQRFTEQILEDDTFSAKYGDLGNVYGSQWRAWKTSTGET
IDQISNVIDMIKNNPNSRRMIVSAWNPEDVPTSALPPCHSLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYALLTELI
AKATGLEVGEFIHTIGDAHIYSNHLDQVKEQLERTPRPAPKLKFKQVHDSIFDYEPGDIVVEGYDPHPTIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-99 63