Gene Information

Name : LVIS_1710 (LVIS_1710)
Accession : YP_795808.1
Strain : Lactobacillus brevis ATCC 367
Genome accession: NC_008497
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1665748 - 1667019 bp
Length : 1272 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAGTTGATTCGCCAAGAACCAGACTTCATCAAAGAAAAGTTGGCAACTCGAGGCGTTGACCCAGCTGA
TATTGATGCACTATTGGAACTTGATGCCAAACGTCGGGAACTAATTGTTAAGAGTGAAACGATGAAAGCCCAACGAAACA
CGGTGTCTGATGAAATTTCACAATTGAAGCGGAATAAAGAAGATGCTGACGACAAGATTAAGGAAATGCGTCAGGTGAGT
GCTGATATCAAAGATATTGATGCGCAATTGGATACATTAAAGGATCAAGTCCAAGATGCTGCCGCGCATTTACCTAATAT
TCCCAACGATAATGTTCCAGTTGGATTAACTGAGGATGGGAGTGTTGAACTCCGCCAATGGGGCGAGAAGCCAAATATGG
ACTTCACGCCTAAAGCACACTACGAAATTGGGGAAGATCTTGGCATCTTAGACTTTGAAGCTGGCGCTAAAGTTTCGGGT
AGTCGGTATCTGTATTATCTGGGTGCCGGTGCGCGGTTGGAACGGGCCGTGTACAACTTTTTCTTGGATGAGAATACCAA
GGCTGGATTTAAGGAAGTCCTGCCACCTTATATCGTGAATGACGATTCGATGTATGGTACGGGCCAATTTCCTAAGTTCA
AGGAAGATGTTTACCAATTAAAGGATGAAGCCATGACCTTGATTCCAACGGCCGAAGTCCCCTTAGTGAACTACTATCGT
GACGAAGTTATTCCTGAAGAAGAACTGCCAGTTTGGTTTACGGCCTTGACCCCAGCTTTCCGGTCTGAAGCCGGTAGTGC
CGGTCGAGATACGCGCGGACTAATTCGGCTGCACCAATTCAATAAGGTTGAGATGGTGAAGTTCTGTAAACCTGAAAATT
CGTGGGCTGAGTTGGAGGCCTTAACCAAGCATGCTGAGAGCCTCTTACAGAAGTTAGGCTTGGCTTACCATGTTATTACC
TTGACGACTAGTGATATGAGCTTTACCGCGGCGATGACGCACGATCTGGAAGTCTGGTTCCCTGAACAACAGACTTATCG
TGAAATTTCAAGTTGTTCGAACACCACGGACTTCCAAGCACGGCGCGCCCACATTCAATATCGTGATGAGAATGGTAAAT
TACAATACGTGCATGCGTTGAACGGTTCCGGTTTGGCGGTTGGCCGGGCAGTTGCTGCGATTTTGGAAAATTATCAAAAT
GCTGATGGTTCCGTCACTATTCCGGATGTTTTAGTGCCTTATATGGGTGGCTTAACTAAGATCACCAAGTAA

Protein sequence :
MLDLKLIRQEPDFIKEKLATRGVDPADIDALLELDAKRRELIVKSETMKAQRNTVSDEISQLKRNKEDADDKIKEMRQVS
ADIKDIDAQLDTLKDQVQDAAAHLPNIPNDNVPVGLTEDGSVELRQWGEKPNMDFTPKAHYEIGEDLGILDFEAGAKVSG
SRYLYYLGAGARLERAVYNFFLDENTKAGFKEVLPPYIVNDDSMYGTGQFPKFKEDVYQLKDEAMTLIPTAEVPLVNYYR
DEVIPEEELPVWFTALTPAFRSEAGSAGRDTRGLIRLHQFNKVEMVKFCKPENSWAELEALTKHAESLLQKLGLAYHVIT
LTTSDMSFTAAMTHDLEVWFPEQQTYREISSCSNTTDFQARRAHIQYRDENGKLQYVHALNGSGLAVGRAVAAILENYQN
ADGSVTIPDVLVPYMGGLTKITK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-135 65