Gene Information

Name : betB (PA14_70950)
Accession : YP_793847.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 6322104 - 6323576 bp
Length : 1473 bp
Strand : -
Note : catalyzes the formation of betaine from betaine aldehyde

DNA sequence :
ATGGCCCGATTCGAAGAACAGAAGCTCTACATTGGCGGTCGCTACGTGGAGGCCAGCAGTGGCGCCACCTTCGAGACCAT
CAACCCGGCCAACGGCGAAGTGCTCGCCAAGGTCCAGCGGGCTTCCAGGGAAGACGTCGAGCGGGCCGTGCAGAGCGCCG
TCGAGGGGCAGAAGGTGTGGGCGGCGATGACCGCCATGCAGCGCTCGCGCATCCTCCGTCGCGCCGTCGACATCCTCCGC
GAGCGCAACGACGAACTGGCCGCCCTGGAAACCCTGGATACCGGCAAGCCGCTGGCGGAAACCCGCTCGGTGGACATCGT
CACCGGCGCCGACGTGCTCGAGTACTACGCCGGCCTGGTCCCGGCCATCGAAGGCGAGCAGATTCCCCTGCGCGAAACCA
GTTTCGTCTACACCCGCCGCGAGCCGCTGGGCGTGGTCGCCGGCATTGGCGCCTGGAACTACCCGGTGCAGATCGCCCTG
TGGAAATCCGCCCCGGCCCTCGCTGCCGGCAACGCGATGATCTTCAAGCCCAGCGAAGTCACCCCGCTGACCACCCTCAA
GCTGGCCGAGATCTACACCGAGGCCGGCGTGCCGGACGGCGTGTTCAACGTGCTCACCGGCAGCGGACGCGAAGTCGGCC
AGTGGCTGACCGAGCACCCGCTGATCGAGAAGATCTCCTTCACCGGCGGCACCTCCACCGGCAAGAAAGTCATGGCCAGC
GCTTCCAGCTCGTCGCTGAAGGAAGTGACCATGGAGCTGGGCGGCAAGTCCCCGCTGATCATCTTCCCCGACGCAGACCT
CGACCGCGCCGCCGACATCGCCGTCATGGCCAACTTCTTCAGCTCCGGCCAGGTCTGCACCAATGGCACCCGGGTGTTCA
TCCACCGTTCCCAGCAGGCCCGCTTCGAAGCCAAGGTACTGGAGCGCGTGCAGCGCATCCGTCTCGGCGACCCGCAGGAC
GAGAACACCAACTTCGGCCCGCTGGTCAGCTTCCCGCACATGGAAAGCGTGCTCGGCTACATCGAGTCCGGCAAGGCGCA
GAAGGCTCGCCTGCTGTGCGGCGGCGAGCGTGTGACCGATGGAGCGTTCGGCAATGGCGCCTACGTCGCGCCGACCGTGT
TCACCGATTGCAGCGACGACATGACCATCGTCCGCGAGGAAATCTTCGGCCCGGTGATGAGCATCCTGGTCTATGACGAC
GAAGACGAGGCGATCCGCCGCGCCAACGATACCGAGTACGGCCTCGCCGCCGGCGTCGTGACCCAGGACCTGGCCCGCGC
CCACCGCGCCATCCATCGCCTGGAAGCCGGCATCTGCTGGATCAATACCTGGGGCGAGTCGCCGGCGGAAATGCCGGTCG
GCGGTTACAAGCAATCCGGTGTCGGTCGCGAGAACGGTCTCACCACCCTGGCTCATTACACTCGCATCAAGTCCGTGCAA
GTGGAGCTGGGCGACTACGCCTCGGTGTTCTGA

Protein sequence :
MARFEEQKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKVWAAMTAMQRSRILRRAVDILR
ERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIEGEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIAL
WKSAPALAAGNAMIFKPSEVTPLTTLKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMAS
ASSSSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEAKVLERVQRIRLGDPQD
ENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAFGNGAYVAPTVFTDCSDDMTIVREEIFGPVMSILVYDD
EDEAIRRANDTEYGLAAGVVTQDLARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQ
VELGDYASVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-76 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-75 41
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-81 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
betB YP_793847.1 betaine aldehyde dehydrogenase VFG0082 Protein 1e-75 41