Gene Information

Name : hemC (PA14_69450)
Accession : YP_793733.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 6193708 - 6194649 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCGTCCCGCGAAATCCGCATCGCCACTCGCCAGAGCGCCCTCGCCTTGTGGCAGGCCGAATACGTCAAGGCGCGCCT
GGAGCAGGCTCATCCTGGCCTGACCGTCACCCTGCTGCCGATGACCAGTCGCGGCGACAAGCTGCTCGACGCACCGCTGG
CGAAGATCGGCGGCAAGGGCCTGTTCGTCAAGGAACTGGAAACCGCCCTGCTCGAAGGCGCCGCCGACATCGCGGTGCAT
TCGATGAAGGACGTGCCGATGGACTTTCCCGAGGGGCTCGGCCTCTACACCATCTGCGAGCGCGAAGACCCGCGTGACGC
TTTCGTCTCGAACACCTACGCCAGCCTCGAGCAACTGCCAGCCGGCAGCGTGGTCGGCACCTCCAGCCTGCGCCGCCAGG
CGCAGCTGCTGGCGCGCCGGCCGGACCTGCAGATCCGTTTCCTGCGGGGCAACGTCAATACCCGCCTGGCCAAGCTGGAT
GCCGGCGAATACGACGCGATCATCCTCGCCGCCGCCGGCCTGATCCGCCTCGGCTTCGAGTCGCGCATCCGCTCCTCGAT
CAGTGTCGACGACAGCCTGCCCGCCGGCGGACAAGGCGCCGTCGGCATCGAATGTCGTACTGCCGACAGCGACTTGCATG
CCTTGCTGGAACCCTTGCACCATTCCGACACGGCTCTGCGGGTCACTGCCGAGCGCGCGCTGAACAAGCGACTCAACGGC
GGTTGCCAGGTGCCGATCGCCTGCTACGCCATCCGCGAGGGCGACCAGCTGTGGCTGCGCGGCCTGGTCGGCCAGCCTGA
TGGCACCCAGTTGCTGCGCGCCGAGGGGCGGGCGCCACTGGCGGAAGCCGAGGCGCTGGGCGTGCGGGTGGCCGAGGACC
TGCTGGAGCAGGGCGCCGAAGCGATTCTCGAAGCCGTCTACGGCGAGGCCGGACATCCGTGA

Protein sequence :
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKGLFVKELETALLEGAADIAVH
SMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLPAGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLD
AGEYDAIILAAAGLIRLGFESRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHSDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAEAILEAVYGEAGHP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-67 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-67 61