Gene Information

Name : cvrA; nhaP2; ycgO (PA14_66380)
Accession : YP_793490.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 5919211 - 5920827 bp
Length : 1617 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGATCGCCGGCAACGATGGGGTCGGCGGCATCGTCTTCGACAACTATCCGGTGGCCTACCTGGTGGGCAACCTGGCGCT
CGCCGTGATCCTCCTCGACGGCGGCCTGCGCACCCGCGTCTCCAGCTTCCGCGTGGCGCTCTGGCCGGCATTGTCGCTGG
CCACCCTGGGCGTGTTGGTGACCACCGGCCTGACCGGCATCGCGGCGGCCTGGCTGTTCGACCTGCACTGGATGGAAGGC
CTGCTGATCGGCGCCATCGTCGGCTCCACCGACGCCGCCGCGGTGTTCTCCCTGCTCGGCGGCAAAGGTCTCAACGAGCG
GGTCACCGCGACCCTGGAGATCGAATCGGGCAGCAACGACCCGATGGCGGTATTCCTCACCGTGACCCTGATCGAGATGC
TCGCCAGCGGCCAGACCGGCCTCAGCTGGGGCTTCGTCCTGCACCTGGTGCAGCAGTTCGGTCTCGGCGCCCTGCTCGGT
CTCGGCGGCGGCTGGTTGCTGCTGCAACTGATCAACCGCATGCACCTGGCCGGCGGCCTCTACCCGCTGCTGGTGATCAG
CGGCGGCCTGCTGGTGTTCGCCCTGGCCAACGCCGTCGGCGGCAGCGGCATCCTGGCCATCTACCTGTGCGGCCTGCTCC
TCGGCAACCGCCCGATCCGCAGCCGCCACGGCATCCTGCACATGCTCGACGGCATGGCCTGGCTGGCGCAGATCGGCATG
TTCCTGGTCCTCGGCCTGCTGGTCACCCCCCACGACCTGTGGCCGATCGCCCTGCCGGCGCTGGCCCTGGCGCTGTGGAT
GATCCTGGTGGCGCGGCCGCTGTCGGTGCTGATCGGACTGATCCCGTTCCGCGCCTTCCACGACCGCGAGAAGGCCTTCA
TCGCCTGGGTCGGCCTGCGCGGCGCGGTGCCGATCATCCTCGCGGTGTTCCCGCTGATGGCCGGCCTGCCGAACGCCCAG
CTGTTCTTCAACGTGGCCTTCTTCATCGTCCTGGTCTCGCTGCTGGTGCAGGGCACCAGCCTGCCCTGGGCGGCCAGGCT
GCTGCGGGTGGTGGTGCCGCCGGACCCGGCACCGATATCCCGCGCCGGCCTGGAGATCCACCCGACCAGCGAGTGGGAGC
TGTTCGTCTACCACCTGAACAAGGAAAAGTGGTGCATCGGCGCCGCCCTGCGCGAGCTGAAGATGCCCGGCGGGACCCGG
ATCGCCGCGCTGTTCCGCGGCACCGAACTGCTCCACCCGTCGGGCAGCACCATCCTCGAGGCCGACGACATCCTCTGCGT
GATCGGCCACGAACACGACCTGCCGGCCCTCGGCAAGCTGTTCAGCCAGGCGCCCGACCGCGGCCTCGGCGCGCGCTTCT
TCGGCGACTTCGTGCTGGAAGGCGATGCCCAGCTGTCGGCGGTGGCCTCGCTCTACGGCCTGAAGCTCGACGGCATCGAC
GGCGAGCAAGCGCTGGGCCGCTTCATCGCCCACGAGATCGGCGGCGAAGCGGTGATCGGCGACCAGGTGGAGTGGAACGG
CCTGACCTGGACCGTGGCCGCCCTGGAAGGCAACCGTATCCGCAAGGTCGGCGTGAAGTTTCCGGAAGGCCGCCCAGGGC
CCGGACTTTTCCTCTGA

Protein sequence :
MIAGNDGVGGIVFDNYPVAYLVGNLALAVILLDGGLRTRVSSFRVALWPALSLATLGVLVTTGLTGIAAAWLFDLHWMEG
LLIGAIVGSTDAAAVFSLLGGKGLNERVTATLEIESGSNDPMAVFLTVTLIEMLASGQTGLSWGFVLHLVQQFGLGALLG
LGGGWLLLQLINRMHLAGGLYPLLVISGGLLVFALANAVGGSGILAIYLCGLLLGNRPIRSRHGILHMLDGMAWLAQIGM
FLVLGLLVTPHDLWPIALPALALALWMILVARPLSVLIGLIPFRAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQ
LFFNVAFFIVLVSLLVQGTSLPWAARLLRVVVPPDPAPISRAGLEIHPTSEWELFVYHLNKEKWCIGAALRELKMPGGTR
IAALFRGTELLHPSGSTILEADDILCVIGHEHDLPALGKLFSQAPDRGLGARFFGDFVLEGDAQLSAVASLYGLKLDGID
GEQALGRFIAHEIGGEAVIGDQVEWNGLTWTVAALEGNRIRKVGVKFPEGRPGPGLFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 2e-145 68
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 2e-145 68