Gene Information

Name : thiC (PA14_65740)
Accession : YP_793441.1
Strain : Pseudomonas aeruginosa UCBPP-PA14
Genome accession: NC_008463
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 5853158 - 5855041 bp
Length : 1884 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCGCAACGCAGAAGAACAACATCACCCGCCTTGAGCAGCTCGACCGCCAGTCGACGCAGCCTTTCCCGAACTCGCG
CAAGGTCTACCTGACCGGCTCGCGCCCGGACATCCGCGTCCCGGTGCGGGAAATCTCCCTCGCCGACACCCCCACCGCCT
TCGGCGGCGAAAAGAACCCGCCGGTGTTCGTCTACGACACCTCCGGCCCGTATACCGACCCCGAGGTCCGCATCGATCTG
CGCAAGGGACTGCCTGACGTGCGTTCGCGCTGGATCGACGAGCGCGGCGACACCGAGATCCTCCCAGGCCTGACCTCCGA
GTTCGGCCAGGCCCGCCTGGCCGACGCCAGCCTCGACGCCCTGCGCTTCGCCCACGTGCGCACGCCGCGCCGGGCCAAGC
CGGGCGCCAACGTCTCGCAGATGCACTACGCGAAGAAGGGCATCATCACCCCGGAGATGGAATACATCGCCATCCGCGAG
AACATGAAGCTGCAGGAAGCCCGGGCCGCCGGCCTGCTCGACCAGCAGCACCCGGGGCACAGCTTCGGTGCCAACACCCC
GAAGGAAATCACCCCCGAGTTCGTCCGCGAGGAAGTCGCCCGCGGCCGCGCGATCATTCCGGCGAACATCAACCACACCG
AGCTTGAGCCGATGATCATCGGCCGCAATTTCCTGGTGAAGATCAACGGCAACATCGGCAACAGCGCGCTGGGCTCGTCG
ATCGAGGAAGAAGTGGAGAAGCTCACCTGGGGCATCCGCTGGGGCGCCGACACGGTGATGGACCTGTCCACCGGCAAGCA
CATCCATGAAACCCGCGAGTGGATCCTGCGCAACAGCCCGGTACCGATCGGCACCGTACCGATCTACCAGGCGCTGGAGA
AGGTCAACGGCGTCGCCGAGGACCTGACCTGGGAAATCTTCCGCGATACCCTGATCGAACAGGCCGAGCAGGGCGTCGAC
TACTTCACCATCCACGCCGGCGTGCTGCTGCGCTATGTGCCGCTGACCGCCAAGCGGGTCACCGGCATCGTTTCCCGCGG
CGGCTCGATCATGGCCAAGTGGTGCCTGGCGCACCACCAGGAGAACTTCCTCTACACGCATTTCGAAGAGATCTGCGAAA
TCATGAAGGCCTACGACGTCAGCTTCTCGCTGGGCGATGGCCTGCGTCCGGGCTCGGTGGCCGACGCCAACGACGCCGCC
CAGTTCGGCGAGCTGGAAACCCTCGGCGAGCTGACCAAGATCGCCTGGAAGCACGACGTGCAGGTGATGATCGAAGGCCC
CGGCCACGTGCCGATGCAATTGATCAAGGAAAACATGGACAAGCAGCTGGAGTGCTGCGACGAGGCGCCGTTCTACACCC
TCGGCCCGCTGACCACCGACATCGCCCCCGGCTACGACCACATCACCTCCGGCATCGGCGCGGCGATGATCGGCTGGTTC
GGCTGCGCCATGCTCTGCTACGTCACGCCCAAGGAGCACCTGGGTCTGCCGAACAAGGATGACGTGAAGACCGGGATCAT
CACCTACAAGATCGCCGCCCATGCCGCCGACCTCGCCAAGGGCCACCCGGGCGCGCAGATCCGCGACAACGCGCTGTCCA
AGGCGCGCTTCGAGTTCCGTTGGGAGGACCAGTTCAACCTTGGCCTGGACCCGGACACCGCGCGGGCGTTCCATGACGAG
ACCCTGCCGAAGGACTCGGCCAAGGTCGCGCACTTCTGCTCCATGTGCGGACCGAAGTTCTGCTCGATGAAGATCACCCA
GGAAGTCCGCGACTACGCCAAGGAGAACGGCCTGTCCGACGAGAGCAAGGCCATCGAGGCCGGCTTCCAGGAGCAGGCGG
CGCGCTTCAAGGACGAAGGATCGGTGATCTACAGGCAGGTGTAG

Protein sequence :
MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDL
RKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRE
NMKLQEARAAGLLDQQHPGHSFGANTPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSS
IEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVD
YFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAA
QFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWF
GCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDE
TLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYRQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 78
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 78
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74